You are viewing an incomplete version of our website. Please click to reload the website as full version.

anti-Meprin A, alpha (PABA Peptide Hydrolase) (MEP1A) Antibodies

alpha subunit of meprin metalloproteases, which form homotetramers and heterodimers with beta subunit Mep1b. Additionally we are shipping Meprin A, alpha (PABA Peptide Hydrolase) Kits (14) and Meprin A, alpha (PABA Peptide Hydrolase) Proteins (10) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
MEP1A 25684 Q64230
MEP1A 17287 P28825
MEP1A 4224 Q16819
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top anti-Meprin A, alpha (PABA Peptide Hydrolase) Antibodies at antibodies-online.com

Showing 10 out of 55 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC (p), WB MEP1A Antibody (N-term) (ABIN652039) western blot analysis in mouse kidney tissue lysates (15 µg/lane). This demonstrates the MEP1A antibody detected MEP1A protein (arrow). MEP1A antibody (N-term) (ABIN652039) immunohistochemistry analysis in formalin fixed and paraffin embedded human colon carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Log in to see 10 to 11 Days
$324.50
Details
Mouse Rabbit Un-conjugated ELISA, WB 100 μg Log in to see 16 Days
$163.90
Details
Human Rabbit Un-conjugated WB WB Image Sample(30 ug whole cell lysate) A:A431, 7.5% SDS PAGE antibody diluted at 1:1000 100 μL Log in to see 2 to 3 Days
$358.60
Details
Mouse Rabbit Un-conjugated IHC (p), ELISA Immunochemical staining of mouse MEP1A in mouse intestine with rabbit monoclonal antibody (5 µg/mL, formalin-fixed paraffin embedded sections). The left panel: tissue incubated with primary antibody; The right panel: tissue incubated with the mixture of p Immunochemical staining of mouse MEP1A in mouse kidney with rabbit monoclonal antibody (5 µg/mL, formalin-fixed paraffin embedded sections). 100 μg Log in to see 16 Days
$273.90
Details
Human Chicken Un-conjugated WB 0.05 mg Log in to see 2 to 3 Days
$446.88
Details
Human Rabbit APC IHC, ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Un-conjugated ICC, IHC (fro), IHC (p), ELISA, WB 100 μg Log in to see 9 to 11 Days
$347.60
Details
Mouse Rabbit Un-conjugated ICC, IHC (fro), IHC (p), ELISA, WB 100 μg Log in to see 9 to 11 Days
$356.40
Details
Human Rabbit Un-conjugated ELISA   200 μL Log in to see 8 to 10 Days
$713.17
Details
Human Rabbit HRP IHC, ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details

MEP1A Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Rat (Rattus) ,


, , , , , , , , , , ,
Mouse (Murine) , ,

,
, , , , , , , , , , ,
Human , , ,
,

, , , , , , , , , , , , , ,

Top referenced anti-Meprin A, alpha (PABA Peptide Hydrolase) Antibodies

  1. Mouse (Murine) Polyclonal MEP1A Primary Antibody for ELISA, WB - ABIN2000231 : Yura, Bradley, Ramesh, Reeves, Bond: Meprin A metalloproteases enhance renal damage and bladder inflammation after LPS challenge. in American journal of physiology. Renal physiology 2008 (PubMed)

More Antibodies against Meprin A, alpha (PABA Peptide Hydrolase) Interaction Partners

Mouse (Murine) Meprin A, alpha (PABA Peptide Hydrolase) (MEP1A) interaction partners

  1. meprin alpha and meprin beta (show MEP1B Antibodies) join the modulators of Reelin (show RELN Antibodies) signalling as they cleave Reelin (show RELN Antibodies) at a specific site and are upregulated under specific pathological conditions.

  2. While meprin A only cleaved protein kinase A (PKA) catalytic subunit beta1, meprin B (show MEP1B Antibodies) cleaved all three PKA catalytic isoforms.

  3. meprin alpha and meprin beta (show MEP1B Antibodies) are unique in their ability to process and release both C- and N-propeptides from type I procollagen (show COL1A2 Antibodies) in vitro and in vivo

  4. the binding of S-MBP to meprins triggers the complement activation through the lectin pathway and may cause the acute renal failure due to ischemia/reperfusion injury on kidney transplantation and hemorrhagic shock

  5. Absence of meprin A aggravates chronic inflammation and lack of meprin B (show MEP1B Antibodies) affords some protection from injury. Manipulation of expression of meprin gene products may have therapeutic potential.

  6. meprin-alpha may play a role in the pathogenesis of diabetic nephropathy and the benefits of ACE (show ACE Antibodies) inhibitor therapy

  7. meprin A, a multimeric metalloprotease (show ADAMTS7 Antibodies) expressed in the brush borders of kidney proximal tubules initially truncates mouse BNP (show BNC2 Antibodies) in the N terminus to mBNP7-32

  8. meprin alpha/beta null (alpha(-/-)/beta(-/-)) mice had decreased prevalence of resident monocytes and natural killer (NK) cells in blood, with a concomitant accumulation of inflammatory monocytes and NK cells in bone marrow.

  9. MEP1A is a UC susceptibility gene and indicate that decreased meprin-alpha expression is associated with intestinal inflammation in IBD patients and in a mouse experimental model of IBD.

Human Meprin A, alpha (PABA Peptide Hydrolase) (MEP1A) interaction partners

  1. Variants rs17468190 (G/T) in the MEP1A gene are associated with glucose and insulin (show INS Antibodies) metabolism in overweight/obese central European women with polycystic ovary syndrome.

  2. Meprin metalloproteases A and B inactivate interleukin 6 (show IL6 Antibodies)

  3. Proteolytically active meprinalpha leads to an increase in EGFR (show EGFR Antibodies) and ERK1/2 (show MAPK1/3 Antibodies) phosphorylation and subsequently enhances cell proliferation and migration

  4. The present results indicate that a TNF-alpha (show TNF Antibodies)-mediated down-regulation of CDX2 (show CDX2 Antibodies) can be related to suppressed expression of MEP1A during intestinal inflammation.

  5. Meprin-alpha activity is regulated differently in primary tumors and metastases of colorectal cancer. By virtue of its pro-migratory and pro-angiogenic activity, meprin-alpha may promote tumor progression in colorectal cancer.

  6. Cystatin C (show CST3 Antibodies) was an inhibitor for human meprin alpha(K(i) = 8.5 x 10(-6) M) but, interestingly, not for meprin beta (show MEP1B Antibodies).

  7. activation in colorectal cancer triggered by the plasminogen (show PLG Antibodies)-activating system

  8. Mephrin beta induced a dramatic change in cell morphology and reduced the cell number, indicating a function in terminal differentiation, whereas meprin alpha did not affect cell viability, and may play a role in basal keratinocyte proliferation.

  9. MEP1A is a UC susceptibility gene and indicate that decreased meprin-alpha expression is associated with intestinal inflammation in IBD patients and in a mouse experimental model of IBD.

Meprin A, alpha (PABA Peptide Hydrolase) (MEP1A) Antigen Profile

Protein Summary

alpha subunit of meprin metalloproteases, which form homotetramers and heterodimers with beta subunit Mep1b

Gene names and symbols associated with MEP1A

  • meprin 1 alpha (Mep1a) antibody
  • meprin A, alpha (PABA peptide hydrolase) (MEP1A) antibody
  • AI098089 antibody
  • AW107200 antibody
  • Mep-1 antibody
  • Mep-1a antibody
  • Mep1 antibody
  • PPHA antibody

Protein level used designations for MEP1A

E-24.18 , MEP-1 , endopeptidase-2 , endopeptidase-24.18 subunit alpha , meprin A alpha , meprin A subunit alpha , meprin A alpha-subunit , meprin alpha , N-benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit alpha , PABA peptide hydrolase , PPH alpha , bA268F1.1 (meprin A alpha (PABA peptide hydrolase))

GENE ID SPECIES
25684 Rattus norvegicus
17287 Mus musculus
4224 Homo sapiens
481826 Canis lupus familiaris
100154136 Sus scrofa
Selected quality suppliers for anti-Meprin A, alpha (PABA Peptide Hydrolase) (MEP1A) Antibodies
Did you look for something else?