You are viewing an incomplete version of our website. Please click to reload the website as full version.

anti-Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF) Antibodies

The protein encoded by MANF is localized in the endoplasmic reticulum (ER) and golgi, and is also secreted. Additionally we are shipping MANF Proteins (25) and MANF Kits (21) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
MANF 7873 P55145
MANF 74840  
MANF 315989  
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top anti-MANF Antibodies at antibodies-online.com

Showing 10 out of 87 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Goat Un-conjugated ELISA, WB ABIN238606 (0.3µg/ml) staining of Human Pancreas lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-MANF Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: HCT15 cell lysate WB Suggested Anti-MANF  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500  Positive Control: HCT15 cell lysate  MANF is supported by BioGPS gene expression data to be expressed in HCT15 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated ICC, IF, WB ICC/IF Image Immunofluorescence analysis of methanol-fixed HepG2, using ARMET, antibody at 1:200 dilution. WB Image Sample(30 μg of whole cell lysate) A:293T 12% SDS PAGE antibody diluted at 1:1500 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of ARMET / ARP Antibody (N-term) in 293 cell line lysates (35ug/lane). This demonstrates the MANF antibody detected the MANF protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated WB MANF Antibody (N-term)  western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the MANF antibody detected the MANF protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Immunohistochemistry of MANF in human brain tissue with this product at 2.5 μg/ml. Western blot analysis of MANF in rat brain tissue lysate with this product at (A) 1 and (B) 2 μg/ml. 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Immunohistochemistry of MANF in human brain tissue with this product at 2.5 μg/ml. Western blot analysis of MANF in mouse brain tissue lysate with this product at (A) 1 and (B) 2 μg/ml. 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Dog Goat Un-conjugated WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Human Mouse Un-conjugated ELISA, WB Western Blot testing of anti-MANF monoclonal antibody. Line 1. Page Ruler prestained protein ladder, Fermentas, Line 2. Purified recombinant MANF (500 ng per line) expressed using CHOEBNALT85  cell line 100 μg Log in to see 7 to 9 Days
$342.00
Details

MANF Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , ,
, ,
,
, , , , ,
Mouse (Murine) ,
,
,
Rat (Rattus) ,
,

Top referenced anti-MANF Antibodies

  1. Human Polyclonal MANF Primary Antibody for ELISA, WB - ABIN238606 : Shridhar, Shridhar, Rivard, Siegfried, Pietraszkiewicz, Ensley, Pauley, Grignon, Sakr, Miller, Smith: Mutations in the arginine-rich protein gene, in lung, breast, and prostate cancers, and in squamous cell carcinoma of the head and neck. in Cancer research 1997 (PubMed)

More Antibodies against MANF Interaction Partners

Fruit Fly (Drosophila melanogaster) Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF) interaction partners

  1. These data suggest a role for Manf in the regulation of Drosophila unfolded protein response.

  2. DmMANF expression in the adult brain is much wider than in the embryonic and larval stages. It is expressed in both glia and neurons including dopaminergic neurons.

  3. study offers further insights into the functional conservation between invertebrate and mammalian MANF/CDNF (show CDNF Antibodies) proteins and reveals the importance of the C-terminal domain for MANF activity in vivo

  4. role of MANF in multicellular organism development

  5. DmMANF is an invertebrate neurotrophic factor (show NTF3 Antibodies) supporting dopaminergic neurons.

Zebrafish Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF) interaction partners

  1. These results suggest that MANF is involved in the regulation of the development of dopaminergic system in zebrafish.

Human Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF) interaction partners

  1. the role of two short sequence motifs within the carboxy-(C) terminal domain of MANF in its neuroprotective activity, was studied.

  2. the selective expression of MANF in splenocytes may be involved in plasma cell differentiation and immune regulation.

  3. MANF is a protein that interacts with RTN1-C (show RTN1 Antibodies)

  4. We demonstrate that Armet and Creld2 (show CRELD2 Antibodies) are genotype-specific ER stress response proteins with substrate specificities, and that aggregation of mutant matrilin-3 (show MATN3 Antibodies) is a key disease trigger in MED that could be exploited as a potential therapeutic target

  5. MANF binding to the plasma membrane also required the RTDL sequence and was inhibited with a peptide known to interact with KDELRs, suggesting MANF binds KDELRs at the surface.

  6. MANF and C-MANF protect neurons intracellularly as efficiently as Ku70.

  7. Pretreatment with adeno (show ADORA2A Antibodies)-associated-virus vector containing human MANF reduces the volume of cerebral infarction and facilitates behavioral recovery in experimental stroke rats.

  8. Armet is a novel secreted mediator of the adaptive pathway of unfolded protein response.

  9. The widespread expression of MANF together with its evolutionary conserved nature and regulation by brain insults suggest that it has important functions both under normal and pathological conditions in many tissue types.

  10. structures of MANF and CDNF (show CDNF Antibodies) were solved; structure explains why MANF and CDNF (show CDNF Antibodies) are bifunctional; neurotrophic activity may reside in the N-terminal domain and ER stress response in the C-terminal domain

Mouse (Murine) Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF) interaction partners

  1. MANF has immune modulatory properties that are required for retinal repair in Drosophila

  2. secretion of mouse MANF and mouse CDNF (show CDNF Antibodies) is fundamentally regulated in the same manner, the variation of four C-terminal amino acids in the MANF and CDNF (show CDNF Antibodies) among species might influence their intracellular functions.

  3. MANF-deficient mice develop severe diabetes, progressive postnatal reduction of beta cell mass and chronic unfolded protein response activation.

  4. Secretion of MANF is regulated via COPII-mediated transport and that its C-terminus could be responsible for its retention in the endoplasmic reticulum through GRP78 (show HSPA5 Antibodies).

  5. The change in Armet expression lasted while the change of Mrpl51 (show MRPL51 Antibodies) disappeared after birth.

  6. the solution structure of ARMET

  7. ARMET is the second fully characterized ERSE-II-dependent gene and likely contributes to quality control of proteins in the endoplasmic reticulum

  8. The widespread expression of MANF together with its evolutionary conserved nature and regulation by brain insults suggest that it has important functions both under normal and pathological conditions in many tissue types.

MANF Antigen Profile

Protein Summary

The protein encoded by this gene is localized in the endoplasmic reticulum (ER) and golgi, and is also secreted. Reducing expression of this gene increases susceptibility to ER stress-induced death and promotes cell proliferation. The protein was initially thought to be longer at the N-terminus and to contain an arginine-rich region but transcribed evidence indicates a smaller open reading frame that does not encode the arginine tract. The presence of polymorphisms in the arginine-rich region, including a specific mutation that changes the previously numbered codon 50 from ATG to AGG, have been reported in a variety of solid tumors\; however, these polymorphisms were later shown to exist in normal tissues and are thus not tumor-related.

Gene names and symbols associated with MANF

  • mesencephalic astrocyte-derived neurotrophic factor (MANF) antibody
  • Mesencephalic astrocyte-derived neurotrophic factor (Manf) antibody
  • mesencephalic astrocyte-derived neurotrophic factor (manf) antibody
  • mesencephalic astrocyte-derived neurotrophic factor (Manf) antibody
  • 3230402M22Rik antibody
  • AA407711 antibody
  • AA408789 antibody
  • AA673178 antibody
  • anon-EST:ParkEST188 antibody
  • Armet antibody
  • ARP antibody
  • ARP-like antibody
  • CG7013 antibody
  • D18Mgi17 antibody
  • D17914 antibody
  • Dmel\\CG7013 antibody
  • DmMANF antibody
  • im:6909481 antibody
  • MANF antibody
  • RBM15B antibody
  • zgc:153327 antibody

Protein level used designations for MANF

mesencephalic astrocyte-derived neurotrophic factor , arginine-rich, mutated in early stage tumors , CG7013-PA , Manf-PA , ARP-like , arginine-rich protein , RNA binding motif protein 15B , chromosome 3p21.1 gene sequence

GENE ID SPECIES
745542 Pan troglodytes
41983 Drosophila melanogaster
549179 Xenopus (Silurana) tropicalis
767691 Danio rerio
7873 Homo sapiens
608421 Canis lupus familiaris
74840 Mus musculus
315989 Rattus norvegicus
540432 Bos taurus
100505460 Sus scrofa
770664 Gallus gallus
100719906 Cavia porcellus
Selected quality suppliers for anti-MANF (MANF) Antibodies
Did you look for something else?