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anti-Mesoderm Posterior 2 Homolog (Mouse) (Mesp2) Antibodies

Mesp2 encodes a member of the bHLH family of transcription factors and plays a key role in defining the rostrocaudal patterning of somites via interactions with multiple Notch signaling pathways. Additionally we are shipping Mesp2 Proteins (2) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
Mesp2 17293 O08574
Mesp2 293046  
Mesp2 145873 Q0VG99
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Top anti-Mesp2 Antibodies at antibodies-online.com

Showing 10 out of 20 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Mouse Rabbit Un-conjugated WB WB Suggested Anti-MESP2 Antibody Titration: 1.25ug/mlELISA Titer: 1:62500Positive Control: SP2/0 cell lysate 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Mouse Un-conjugated ELISA, WB Figure 1: Red: Control Antigen (100 ng), Purple: Antigen (10ng), Green: Antigen (50 ng), Blue: Antigen (100 ng) Figure 2: Western blot analysis using MESP2 mAb against human MESP2 recombinant protein. (Expected MW is 31.4 kDa) 0.1 mg Log in to see 3 to 4 Days
$430.10
Details
Mouse Rabbit Un-conjugated WB 100 μg Log in to see 8 to 10 Days
$493.17
Details
Human Rabbit Un-conjugated WB Western blot analysis of MESP2 expression in A549 (A), NS-1 (B), H9C2 (C) whole cell lysates. 200 μL Log in to see 9 Days
$487.50
Details
Human Mouse Un-conjugated ELISA, WB 100 μg Log in to see 8 to 10 Days
$551.83
Details
Mouse Rabbit Un-conjugated ELISA, WB 100 μg Log in to see 2 to 3 Days
$343.75
Details
Human Mouse Un-conjugated IF, ELISA Immunofluorescence of monoclonal antibody to MESP2 on HeLa cell. [antibody concentration 10 ug/ml] 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated WB   100 μL Log in to see 8 to 10 Days
$375.83
Details
Mouse Rabbit Un-conjugated WB MESP2 antibody (20R-1126) used at 0.2-1 ug/ml to detect target protein. 100 μg Log in to see 7 to 9 Days
$407.14
Details
Human Mouse Un-conjugated ELISA   100 μg Log in to see 9 Days
$430.00
Details

Mesp2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Mouse (Murine)


Rat (Rattus)


Human ,
,
,

Top referenced anti-Mesp2 Antibodies

  1. Mouse (Murine) Polyclonal Mesp2 Primary Antibody for WB - ABIN2779870 : Morimoto, Takahashi, Endo, Saga: The Mesp2 transcription factor establishes segmental borders by suppressing Notch activity. in Nature 2005 (PubMed)
    Show all 2 references for ABIN2779870

  2. Human Monoclonal Mesp2 Primary Antibody for ELISA, WB - ABIN1098148 : Qiu, Zhou, Jiang, Ji, Ding, Lv, Liu, Tang, Cheng, Qiu: Mutation analysis of MESP2, HES7 and DUSP6 gene exons in patients with congenital scoliosis. in Studies in health technology and informatics 2012 (PubMed)
    Show all 2 references for ABIN1098148

More Antibodies against Mesp2 Interaction Partners

Mouse (Murine) Mesoderm Posterior 2 Homolog (Mouse) (Mesp2) interaction partners

  1. Studies indicate that mesodermal posterior 1 (Mesp1 (show MESP1 Antibodies)) and mesodermal posterior 2 (Mesp2) double-knockout embryos exhibited defective development of the embryonic mesoderm.

  2. conclusion was supported by analyses of Mesp2 KO and Ripply1/2 double KO embryos lacking rostral and caudal (show CAD Antibodies) properties, respectively

  3. current observations of the spatiotemporal disorder of vertebral organogenesis in the Mesp2-null mice provide further insight into the pathogenesis of SCDO and STDO, and the physiological development of the axial skeleton

  4. Data demonstrate that Mesp2 is a novel component involved in the suppression of Notch (show NOTCH1 Antibodies) target genes.

  5. Data propose a novel function of Notch (show NOTCH1 Antibodies) signaling, in which a progressive oscillating wave of Notch (show NOTCH1 Antibodies) activity is translated into the rostral-caudal (show CAD Antibodies) polarity of a somite by regulating Mesp2 expression in the anterior presomitic mesoderm.

  6. A bHLH-type transcription factor, Mesp2, plays an essential role in somite segmentation in mice.

  7. Data describe the genetic interactions between Dll1 (show DLL1 Antibodies), Dll3 (show DLL3 Antibodies), Mesp2 and Psen1 (show PSEN1 Antibodies), and the roles of Dll1 (show DLL1 Antibodies)- and Dll3 (show DLL3 Antibodies)-Notch (show NOTCH1 Antibodies) pathways, with or without Psen1 (show PSEN1 Antibodies), in rostrocaudal patterning.

  8. Mesp2 is responsible for the rostro-caudal (show CAD Antibodies) patterning process itself in the anterior presomitic mesoderm, via cellular interaction.

  9. developmental protein "wavefront" is generated by suppression of Notch (show NOTCH1 Antibodies) activity by mesoderm posterior 2 (Mesp2) through induction of the lunatic fringe (show LFNG Antibodies) gene (Lfng (show LFNG Antibodies))

  10. Tbx6 (show TBX6 Antibodies) directly binds to the Mesp2 gene upstream region and mediates Notch (show NOTCH1 Antibodies) signaling, and subsequent Mesp2 transcription, in the anterior presomitic mesoderm.

Human Mesoderm Posterior 2 Homolog (Mouse) (Mesp2) interaction partners

  1. MESP2, HES7 and DUSP6 genes may not be involved in the etiopathogenesis of sporadic and non-syndromic CS in Chinese Han population.

  2. Mutated MESP2 causes spondylocostal dysostosis

  3. Mesp1 (show MESP1 Antibodies) is down-regulated in the later stages of development by increasing levels of Mesp2 in the wild-type embryo.

  4. findings suggest a founder-effect mutation in the MESP2 gene as a major cause of the classical Puerto Rican form of spondylothoracic dysostosis/Jarcho-Levin syndrome

Mesp2 Antigen Profile

Protein Summary

This gene encodes a member of the bHLH family of transcription factors and plays a key role in defining the rostrocaudal patterning of somites via interactions with multiple Notch signaling pathways. This gene is expressed in the anterior presomitic mesoderm and is downregulated immediately after the formation of segmented somites. This gene also plays a role in the formation of epithelial somitic mesoderm and cardiac mesoderm. Mutations in the MESP2 gene cause autosomal recessive spondylocostal dystosis 2 (SCD02).

Gene names and symbols associated with Mesp2

  • mesoderm posterior 2 (MESP2) antibody
  • mesoderm posterior 2 (Mesp2) antibody
  • mesoderm posterior 2 homolog (mouse) (Mesp2) antibody
  • mesoderm posterior 2 homolog (mouse) (MESP2) antibody
  • bHLHc6 antibody
  • SCDO2 antibody

Protein level used designations for Mesp2

mesoderm posterior 2 , mesoderm posterior protein 2 , class C basic helix-loop-helix protein 6

GENE ID SPECIES
100015370 Monodelphis domestica
17293 Mus musculus
293046 Rattus norvegicus
145873 Homo sapiens
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