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anti-Mesoderm Specific Transcript (MEST) Antibodies

MEST encodes a member of the alpha/beta hydrolase superfamily. Additionally we are shipping MEST Kits (5) and MEST Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
MEST 17294 Q07646
MEST 58827 Q6P5P5
MEST 4232 Q5EB52
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Top anti-MEST Antibodies at antibodies-online.com

Showing 10 out of 24 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Goat Un-conjugated EIA, WB Anti-MEST (0.2µg/ml) staining of Mouse Testis lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Mouse Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Human Goat Un-conjugated ELISA, WB 100 μg Log in to see 8 to 10 Days
$595.83
Details
Mouse Goat Un-conjugated ELISA, WB   100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Rabbit Un-conjugated IF   50 μL Log in to see 8 to 10 Days
$390.50
Details
Human Rabbit Un-conjugated IHC, WB   100 μL Log in to see 14 Days
$527.15
Details
Human Goat FITC ELISA, WB   100 μL Log in to see 16 Days
$713.43
Details
Human Goat PE ELISA, WB   100 μL Log in to see 16 Days
$713.43
Details
Human Goat Alkaline Phosphatase (AP) ELISA, WB   100 μL Log in to see 16 Days
$713.43
Details
Human Goat APC ELISA, WB   100 μL Log in to see 16 Days
$713.43
Details

MEST Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine)
,

Rat (Rattus)
,

Human ,
,

, , , , ,

Top referenced anti-MEST Antibodies

  1. Cow (Bovine) Polyclonal MEST Primary Antibody for EIA, WB - ABIN615910 : Li, Vu, Lee, Yang, Nguyen, Bui, Zeng, Nguyen, Hu, Murphy, Jirtle, Hoffman: An imprinted PEG1/MEST antisense expressed predominantly in human testis and in mature spermatozoa. in The Journal of biological chemistry 2002 (PubMed)

More Antibodies against MEST Interaction Partners

Mouse (Murine) Mesoderm Specific Transcript (MEST) interaction partners

  1. Although both Mest and miR (show MLXIP Antibodies)-335 are highly expressed during muscle development and regeneration, only Mest+/- (maternal/paternal) mice show retardation of body growth.

  2. The paternally expressed imprinted gene Mest was only detected in haploid androgenetic blastocysts and was significantly lower in this group relative to the controls, indicating that the gene maintains expression patterns specific to its parental origin.

  3. analysis of modifications of H3 histone (show HIST1H3B Antibodies) in H19 (show NCKAP1 Antibodies) and MEST imprinted genes in blastocysts produced in vitro from non-vitrified and vitrified two-cell embryos

  4. Results suggest that at least one allele of Mest expression is required in the somatic tissues of adult individuals and that under certain conditions (such as in the presence of a Mest insertional mutation or in an altered genetic background), somatically acquired alterations of allelic expression at the Mest locus may occur.

  5. The data showed that Mest expression was regulated through cAMP-dependent protein kinase A pathways during differentiation of preadipocytes into adipocytes in vitro, supporting the critical role of Mest in proliferation and differentiation of adipocytes.

  6. The identification of new imprinted RNA products at the Mest locus, longer variants of the RNA, called MestXL, transcribed >10 kb into the downstream antisense gene Copg2 (show COPG2 Antibodies).

  7. Mest/Peg1 is a novel down-regulator of Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) signalling during adipogenic differentiation.

  8. Mest/Peg1 gene is imprinted, with preferential expression from the paternal allele.

  9. These data suggest that mechanisms independent of the CpG methylation status of the Mest promoter must underlie the control of its expression during adipose tissue expansion.

  10. MEST, a gene with a putative mesenchymal cell-derived protein, conceivably plays a role in mammalian metanephric development

Human Mesoderm Specific Transcript (MEST) interaction partners

  1. altered DNA methylation (show HELLS Antibodies) at imprinted domains including IGF2/H19 (show NCKAP1 Antibodies) and PEG1/MEST may mediate the association between human papillomavirus infection and invasive cervical cancer

  2. The expression levels of miR (show MLXIP Antibodies)-335 significantly correlated with those of MEST, supporting the notion that the intronic miR (show MLXIP Antibodies)-335 is co-expressed with its host gene

  3. DNA methylation (show HELLS Antibodies) level at the H19 (show NCKAP1 Antibodies) and MEST differentially methylated regions (DMRs)is reduced in placentas from pregnancies conceived by IVF (show SCN5A Antibodies)/ICSI when compared with placentas from spontaneous conception.

  4. Paternal methylation aberrations at imprinting control regions of DLK1 (show DLK1 Antibodies)-GTL2, MEST (PEG1), and ZAC (PLAGL1 (show PLAGL1 Antibodies)) and global methylation levels are not associated with idiopathic recurrent spontaneous miscarriages.

  5. Data indicate that ARMCX2 (show ARMCX2 Antibodies), COL1A1 (show COL1A1 Antibodies), MDK (show MDK Antibodies), MEST and MLH1 (show MLH1 Antibodies) genes acquired methylation in drug-resistant ovarian cancer-sustaining (side population) cells.

  6. MEST showed tissue-specific imprinting, being paternally expressed in skeletal muscle, fat, pituitary gland, heart, kidney, lung, stomach and uterus, and maternally expressed in spleen and liver.

  7. In cortices, the MEST promoter was hemimethylated, as expected for a differentially methylated imprinting control region, whereas the COPG2 and TSGA14 promoters were completely demethylated, typical for transcriptionally active non-imprinted genes.

  8. Regardless of conception method, the PEG1 methylation percentage in chorionic villus from spontaneous abortions is significantly higher than in villus from induced abortions and multifetal reduction.

  9. data demonstrated that tumorigenesis of leiomyoma is associated with overexpression of isoform 1 of PEG1/MEST gene, but not with loss of imprinting of the gene

  10. MEST gene is imprinted in an isoform-specific manner in adult lymphocytes.

MEST Antigen Profile

Protein Summary

This gene encodes a member of the alpha/beta hydrolase superfamily. It is imprinted, exhibiting preferential expression from the paternal allele in fetal tissues, and isoform-specific imprinting in lymphocytes. The loss of imprinting of this gene has been linked to certain types of cancer and may be due to promotor switching. The encoded protein may play a role in development. Alternatively spliced transcript variants encoding multiple isoforms have been identified for this gene. Pseudogenes of this gene are located on the short arm of chromosomes 3 and 4, and the long arm of chromosomes 6 and 15.

Gene names and symbols associated with MEST

  • mesoderm specific transcript (Mest) antibody
  • mesoderm specific transcript (MEST) antibody
  • mesoderm specific transcript homolog (mouse) (MEST) antibody
  • AA408879 antibody
  • AI256745 antibody
  • PEG1 antibody

Protein level used designations for MEST

mesoderm-specific transcript protein , paternally-expressed gene 1 protein , mesoderm specific transcript homolog , mesoderm-specific transcript homolog protein

GENE ID SPECIES
17294 Mus musculus
58827 Rattus norvegicus
4232 Homo sapiens
607717 Canis lupus familiaris
404180 Bos taurus
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