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anti-Metalloproteinase Inhibitor 1 (TIMP1) Antibodies

TIMP1 belongs to the TIMP gene family. Additionally we are shipping TIMP1 Kits (126) and TIMP1 Proteins (67) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TIMP1 7076 P01033
TIMP1 116510 P30120
TIMP1 21857 P12032
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Top anti-TIMP1 Antibodies at antibodies-online.com

Showing 10 out of 269 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated FACS, IF, IHC (p), WB Western blot analysis of TIMP1 Antibody (N-term) (ABIN390664) in CEM cell line lysates (35 µg/lane). TIMP1 (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human breast carcionma reacted with TIMP1 Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, IF, IHC (p), WB Confocal immunofluorescent analysis of TIMP1 Antibody (C-term) with A2058 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue). TIMP1 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of TIMP1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated EIA, WB Formalin-fixed and paraffin-embedded human breast carcionma reacted with TIMP1 Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. Western blot analysis of TIMP1 Antibody (N-term) in CEM cell line lysates (35ug/lane). TIMP1 (arrow) was detected using the purified Pab. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Mouse PE FACS Detection of TIMP-1 in NS0 Mouse Cell Line transfected with human TIMP-1 by Flow Cytometry. NS0 mouse myeloma cell line transfected with human TIMP-1 was stained with Mouse Anti-Human TIMP-1 PE-conjugated Monoclonal Antibody. 100 Tests Log in to see 6 to 7 Days
$393.75
Details
Human Mouse Un-conjugated ELISA (Capture), FACS, IHC, WB TIMP-1 in Human Astrocytoma. TIMP-1 was detected in immersion fixed paraffin-embedded sections of human astrocytoma using Human TIMP-1 Monoclonal Antibody. 100 μg Log in to see 6 to 7 Days
$367.50
Details
Human Rabbit Un-conjugated IF (cc), IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human colon carcinoma labeled with Rabbit Anti-TIMP-1(NT) Polyclonal Antibody, Unconjugated (ABIN668331) at 1:200 followed by conjugation to the secondary antibody and DAB staining. Formalin-fixed and paraffin embedded rabbit liver tissue labeled with Rabbit Anti-TIMP-1(NT) Polyclonal Antibody, Unconjugated (ABIN668331) at 1:200 followed by conjugation to the secondary antibody and DAB staining. 100 μL Log in to see 3 to 7 Days
$307.45
Details
Cow Rabbit Un-conjugated IHC, ELISA, WB 0.1 mg Log in to see 2 to 6 Days
$327.00
Details
Cow Mouse Un-conjugated EIA, IHC (p), WB Staining of Human prostatic adenocarcinoma with TIMP1 Antibody Cat.-No AF2310 (Clone 7-6C1) at 2 µg/ml. Antibody positive in cytoplasma and in lumen secreted. 10x Staining of Human prostatic adenocarcinoma with TIMP1 Antibody Cat.-No AF2310 (Clone 7-6C1) at 2 µg/ml. Antibody positive in cytoplasma and in lumen secreted. 40x 0.1 mg Log in to see 6 to 8 Days
$247.50
Details
Human Rabbit Un-conjugated IHC (p) 7 mL Log in to see 21 to 31 Days
$164.00
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL Log in to see 14 Days
$175.80
Details

TIMP1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-TIMP1 Antibodies

  1. Human Monoclonal TIMP1 Primary Antibody for ELISA (Capture), FACS - ABIN4899800 : Li, Hou, Shao, Tang, Li: The DSCs-expressed CD82 controls the invasiveness of trophoblast cells via integrinbeta1/MAPK/MAPK3/1 signaling pathway in human first-trimester pregnancy. in Biology of reproduction 2010 (PubMed)
    Show all 13 references for ABIN4899800

  2. Human Polyclonal TIMP1 Primary Antibody for IF (cc), IF (p) - ABIN668331 : Sassoli, Nosi, Tani, Chellini, Mazzanti, Quercioli, Zecchi-Orlandini, Formigli: Defining the role of mesenchymal stromal cells on the regulation of matrix metalloproteinases in skeletal muscle cells. in Experimental cell research 2014 (PubMed)
    Show all 6 references for ABIN668331

  3. Cow (Bovine) Polyclonal TIMP1 Primary Antibody for IHC, ELISA - ABIN1582210 : Pitteri, Kelly-Spratt, Gurley, Kennedy, Buson, Chin, Wang, Zhang, Wong, Chodosh, Nelson, Hanash, Kemp: Tumor microenvironment-derived proteins dominate the plasma proteome response during breast cancer induction and progression. in Cancer research 2011 (PubMed)
    Show all 3 references for ABIN1582210

  4. Human Polyclonal TIMP1 Primary Antibody for EIA, WB - ABIN453420 : Safranek, Pesta, Holubec, Kulda, Dreslerova, Vrzalova, Topolcan, Pesek, Finek, Treska: Expression of MMP-7, MMP-9, TIMP-1 and TIMP-2 mRNA in lung tissue of patients with non-small cell lung cancer (NSCLC) and benign pulmonary disease. in Anticancer research 2009 (PubMed)
    Show all 3 references for ABIN453420

  5. Cow (Bovine) Monoclonal TIMP1 Primary Antibody for EIA, IHC (p) - ABIN567563 : Kodama, Kishi, Obata, Iwata, Hayakawa: Monoclonal antibodies to bovine collagenase inhibitor. in Collagen and related research 1988 (PubMed)
    Show all 2 references for ABIN567563

  6. Human Polyclonal TIMP1 Primary Antibody for FACS, IF - ABIN390664 : Wu, Wang, Guo, Ye, Wang, Yuan, Yao, Shang: A lipoxin A4 analog ameliorates blood-brain barrier dysfunction and reduces MMP-9 expression in a rat model of focal cerebral ischemia-reperfusion injury. in Journal of molecular neuroscience : MN 2012 (PubMed)
    Show all 2 references for ABIN390664

  7. Human Monoclonal TIMP1 Primary Antibody for FACS - ABIN4896673 : Domeij, Modéer, Quezada, Yucel-Lindberg: Cell expression of MMP-1 and TIMP-1 in co-cultures of human gingival fibroblasts and monocytes: the involvement of ICAM-1. in Biochemical and biophysical research communications 2005 (PubMed)

  8. Human Polyclonal TIMP1 Primary Antibody for EIA, IF - ABIN955221 : Lin, Yang, Chung, Lee: Functional polymorphisms in matrix metalloproteinases-1, -3, -9 are associated with arteriovenous fistula patency in hemodialysis patients. in Clinical journal of the American Society of Nephrology : CJASN 2010 (PubMed)

More Antibodies against TIMP1 Interaction Partners

Cow (Bovine) Metalloproteinase Inhibitor 1 (TIMP1) interaction partners

  1. Decreased MMP-9 (show MMP9 Antibodies) and increased TIMP-1 expression were found in peripheral blood cells from Mycobacterium avium subsp. paratuberculosis (Map)-infected cattle after stimulation with Map lysate and Map purified protein derivative than in control cattle.

  2. We used a trophoblast cell line (F3) derived from bovine placentomes to examine the influence of EGF (show EGF Antibodies) on MMP-9 (show MMP9 Antibodies) and TIMP-1 expression by semiquantitative RT-PCR and MMP activity by zymography.

  3. Production of TIMP-1 was augmented by IL-1alpha, TNFalpha (show TNF Antibodies), and hepatocyte growth factor (show HGF Antibodies) at level of translation and was transcriptionally increased by 12-O-tetradecanoylphorbol 13-acetate. Level of TIMP-2 (show TIMP2 Antibodies) mRNA was not affected by any treatments.

  4. the different temporal expression patterns of TIMP-1 and TIMP-2 (show TIMP2 Antibodies) suggest that TIMP-1 may be important for luteal formation and development, while TIMP-2 (show TIMP2 Antibodies) may play significant roles during luteal development and maintenance

  5. analysis of species specificity of human and bovine TIMP-1 binding to mouse TIMP-1 receptor

Human Metalloproteinase Inhibitor 1 (TIMP1) interaction partners

  1. The tumor/stroma TIMP-1 intensity ratio in tissue is useful to predict tumor recurrence in non-small cell lung cancer.

  2. Expression of TIMP-1 was significantly reduced in unstable carotid plaques compared with stable ones.

  3. TIMP-1 and-2 are primarily markers of an early function of the transplanted kidney.

  4. Increased expression ratio of MMP9 (show MMP9 Antibodies)/TIMP-1 was observed in relapsing-remitting multiple sclerosis patients that responded to IFN-beta (show IFNB1 Antibodies) therapy.

  5. High expression of TIMP-1 is associated with cardiovascular complications.

  6. MMP-9 (show MMP9 Antibodies) activation rather than TIMP-1 may by associated with the pathomechanism of retinal ganglion cell and optic nerve damage in absolute glaucoma.

  7. Here we report isothermal titration calorimetric studies of the effects of selectivity-modifying mutations in NTIMP1 and NTIMP2 on the thermodynamics of their interactions with MMP1 (show MMP1 Antibodies), MMP3 (show MMP3 Antibodies), and MMP14 (show MMP14 Antibodies).

  8. Normalization of bone marrow microenvironment is paralleled by decreased expression of TIMP and PDGFA (show PDGFA Antibodies).

  9. significant differences were detected concerning the activity of TIMPs resulting in a negative correlation of TIMP1 activity with MMP2 (show MMP2 Antibodies) activity (p = 0.044) and negative correlations of TIMP2 (show TIMP2 Antibodies) and TIMP3 (show TIMP3 Antibodies) with MMP9 (show MMP9 Antibodies) activity

  10. activation of TLR7 upregulated the expression levels of IFN-lambda1 and MMP-9 were increased by ~3 fold, whereas other genes (p53, PTEN, TIMP-1) were upregulated by ~2 fold, and VEGF was marginally upregulated after 10 min.

Pig (Porcine) Metalloproteinase Inhibitor 1 (TIMP1) interaction partners

  1. we demonstrated the presence of high molecular weight (HMW) complexes (130, 170, and 220 kDa) containing MMP9 (show MMP9 Antibodies), TIMP1, and NGAL (show LCN2 Antibodies) (also MMP2 (show MMP2 Antibodies) in 220 kDa complex) without proteolytic activity.

  2. Hemodialysis graft placement leads to early increases in wall shear stress, VEGF-A (show VEGFA Antibodies), pro-MMP-9 (show MMP9 Antibodies), MMP-2 (show MMP2 Antibodies), VEGFR-1 (show FLT1 Antibodies), VEGFR-2 (show KDR Antibodies), and TIMP-1, which may contribute to the development of venous stenosis.

  3. Results indicate that leukemia inhibitory factor (LIF (show LIF Antibodies)) and Oncostatin M (show OSM Antibodies) increase the expression of MMP-1 (show MMP1 Antibodies), MMP-3 (show MMP3 Antibodies), and TIMP-1 several fold, and that their expression is reduced to basal levels in the presence of the LIF (show LIF Antibodies) antagonist MH35-BD.

Mouse (Murine) Metalloproteinase Inhibitor 1 (TIMP1) interaction partners

  1. TIMP-1 was identified as a selectively upregulated component secreted from immature astrocytes from human pluripotent stem cells.

  2. demonstrate that TIMP-2 (show TIMP2 Antibodies) plays a greater protective role than TIMP-1 during the pathogenesis of atherosclerosis

  3. Our findings reveal that elevated levels of TIMP-1 impact on neutrophil homeostasis via signaling through CD63 (show CD63 Antibodies).

  4. TIMP-1 is a ligand of LRP-1 (show LRP1 Antibodies) and we highlight a new example of its MMP-independent, cytokine-like functions.

  5. RAB37 (show RAB37 Antibodies) regulates the exocytosis of TIMP1 in a nucleotide-dependent manner to inactivate MMP9 (show MMP9 Antibodies) migration axis in vitro and in vivo and to suppress tumor metastasis.

  6. PDGF-D (show PDGFD Antibodies) intensifies fibrogenesis by interfering with the fibrolytic activity of the TIMP-1/MMP-2 (show MMP2 Antibodies)/MMP (show MMP2 Antibodies)-9 (show MMP9 Antibodies) system, and PDGF-D (show PDGFD Antibodies) signaling is mediated through both PDGF (show PDGFA Antibodies)-alpha and -beta receptors.

  7. Reduced beta(2)GP I plays a role in diabetic mice related to vascular protection, inhibiting vascular lipid deposition, and plaque formation by reducing MMPs/TIMPs expression through down-regulation of the p38MAPK (show MAPK14 Antibodies) signaling pathway.

  8. Expansion of stem cells counteracts age-related mammary regression in compound Timp1/Timp3 (show TIMP3 Antibodies)-deficient mice.

  9. TNF-alpha (show TNF Antibodies) produced by cholestasis can promote liver fibrosis via TIMP-1 production from hepatic stellate cells.

  10. These data suggest an MMP-independent role of TIMP-1 in regulating CD4 (show CD4 Antibodies) T cell access into the CNS parenchyma during acute JHMV encephalitis

Rabbit Metalloproteinase Inhibitor 1 (TIMP1) interaction partners

  1. Hemoperfusion could obviously reduce oxidative stress and the expression levels of MMP-2 (show MMP2 Antibodies), MMP-9 (show MMP9 Antibodies) and TIMP-1 in rabbits with acute paraquat poisoning.

TIMP1 Antigen Profile

Protein Summary

This gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction.

Gene names and symbols associated with TIMP1

  • TIMP metallopeptidase inhibitor 1 (TIMP1) antibody
  • TIMP metallopeptidase inhibitor 1 (Timp1) antibody
  • tissue inhibitor of metalloproteinase 1 (Timp1) antibody
  • tissue inhibitor of metalloproteinase 1 (LOC100009047) antibody
  • Clgi antibody
  • EPA antibody
  • EPO antibody
  • HCI antibody
  • Timp antibody
  • TIMP-1 antibody
  • TIMP1 antibody

Protein level used designations for TIMP1

EG-1 , TIMP-1 , embryogenin-1 , metalloproteinase inhibitor 1 , tissue inhibitor of metalloproteinase 1 (erythroid potentiating activity, collagenase inhibitor) , tissue inhibitor of metalloproteinases 1 , tissue inhibitor of matrix metalloproteinase-1 , tissue inhibitor of metalloproteinase 1 , collagenase inhibitor , erythroid potentiating activity , erythroid-potentiating activity , fibroblast collagenase inhibitor , metalloproteinase tissue inhibitor 1 , tissue inhibitor of metallopeptidase 1 , metalloproteinase tissue inhibitor , EPA , TPA-S1 , TPA-induced protein , collagenase inhibitor 16C8 fibroblast , tissue inhibitor of metalloproteinase-1

GENE ID SPECIES
282092 Bos taurus
403816 Canis lupus familiaris
7076 Homo sapiens
396862 Sus scrofa
116510 Rattus norvegicus
443331 Ovis aries
21857 Mus musculus
100009047 Oryctolagus cuniculus
100034220 Equus caballus
574348 Macaca mulatta
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