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Metastasis Associated 1 (MTA1) ELISA Kits

MTA1 encodes a protein that was identified in a screen for genes expressed in metastatic cells, specifically, mammary adenocarcinoma cell lines. Additionally we are shipping MTA1 Antibodies (101) and MTA1 Proteins (7) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
MTA1 9112 Q13330
MTA1 116870  
MTA1 64520 Q62599
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More ELISA Kits for MTA1 Interaction Partners

Human Metastasis Associated 1 (MTA1) interaction partners

  1. MTA1 is up-regulated in CRC (show CALR ELISA Kits); its expression is inversely associated with lymphatic metastases and the expression of VEGFC (show VEGFC ELISA Kits), VEGFD (show Figf ELISA Kits) and VEGFR3 (show FLT4 ELISA Kits)

  2. We revealed a new molecular mechanism of MTA1-mediated invasion and metastasis in lung cancer through downstream target EpCAM (show EPCAM ELISA Kits), and interfering with EpCAM (show EPCAM ELISA Kits) function may be a novel therapeutic strategy for treatment of MTA1-overexpressing lung carcinoma

  3. MTA1 plays an important role in Epithelial-to-mesenchymal transition (EMT (show ITK ELISA Kits)) to promote metastasis via suppressing E-cadherin (show CDH1 ELISA Kits) expression, resulting in a poor prognosis in MPM. MTA1 is a novel biomarker and indicative of a poor prognosis in MPM patients

  4. Inhibition of MTA1 by ERalpha (show ESR1 ELISA Kits) contributes to protection hepatocellular carcinoma from tumor proliferation and metastasis

  5. protein abundance of YB-1 (show YBX1 ELISA Kits) and MTA1, irrespective of DNA or mRNA status, can predict for prostate cancer relapse and uncover a vast underappreciated repository of biomarkers regulated at the level of protein expression.

  6. RNAi aiming at MTA1 can effectively inhibit the expression of MTA1 in endometrial carcinoma Ishikawa cells

  7. report demonstrates that miR (show MLXIP ELISA Kits)-125a-3p inhibits the proliferation, migration, and invasion of NSCLC cells through down-regulation of MTA1

  8. MTA1 drove a global decondensation of chromatin structure, it changed the expression of only a small proportion of genes.

  9. MTA1 is associated with the aggressive nature of pituitary tumors and may be a potential therapeutic target in this tumor type.

  10. MTA1 dysregulation in a subset of salivary gland cancer might promote aggressive phenotypes by compromising the tumor suppressor activity of ERbeta (show ESR2 ELISA Kits)

Mouse (Murine) Metastasis Associated 1 (MTA1) interaction partners

  1. Inhibition of MTA1 expression by in vivo siRNA treatment exacerbated the pathology of LPS (show TLR4 ELISA Kits)-induced acute lung injury, by selectively promoting the expression of NF-kappaB (show NFKB1 ELISA Kits)-regulated inflammatory cytokines.

  2. MTA1 was regulated by HIF-1alpha (show HIF1A ELISA Kits) in hypoxia circumstance to suppress osteoblast differentiation.

  3. MTA1 levels were increased in monosodium urate crystal-induced inflammation.

  4. The inhibition of MTA1 gene could depress the growth and metastasis of laryngeal squamous cell carcinoma in nude mice.

  5. Data suggest that nuclear metastasis-associated protein 1 (MTA1) is a good marker for cancer differentiation diagnosis and a potential target for the treatment of cancers.

  6. this study reports the potential signaling events related to up-regulation of metastasis associated protein 1 (Mta1), a master chromatin modifier, during mono-(2-ethylhexyl) phthalate (MEHP)-induced Sertoli cells injury.

  7. MTA1 has an important role in the maintenance of circadian rhythmicity.

  8. the MTA1/NFkappaB/FasL (show FASL ELISA Kits) circuit may serve as an important defensive/repairing mechanism to help to control the germ cell quality after Sertoli cell injury.

  9. MTA1 is a major contributor to prostate tumor malignant progression.

  10. Data indicate that metastasis tumor antigen 1 (MTA1)-dependent stimulation of STAT3 transcription through action on the MTA1/STAT3/Pol II coactivator complex.

Zebrafish Metastasis Associated 1 (MTA1) interaction partners

  1. Findings suggest that Mta3-NuRD complex, inclding component HDAC1 (show HDAC1 ELISA Kits), is essential for the initiation of primitive hematopoiesis.

MTA1 Antigen Profile

Antigen Summary

This gene encodes a protein that was identified in a screen for genes expressed in metastatic cells, specifically, mammary adenocarcinoma cell lines. Expression of this gene has been correlated with the metastatic potential of at least two types of carcinomas although it is also expressed in many normal tissues. The role it plays in metastasis is unclear. It was initially thought to be the 70kD component of a nucleosome remodeling deacetylase complex, NuRD, but it is more likely that this component is a different but very similar protein. These two proteins are so closely related, though, that they share the same types of domains. These domains include two DNA binding domains, a dimerization domain, and a domain commonly found in proteins that methylate DNA. The profile and activity of this gene product suggest that it is involved in regulating transcription and that this may be accomplished by chromatin remodeling. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with MTA1

  • metastasis associated 1 (MTA1) antibody
  • metastasis associated 1 (mta1) antibody
  • metastasis associated 1 (Mta1) antibody
  • metastasis associated 1 family, member 3 (mta3) antibody
  • fj99h01 antibody
  • mta1 antibody
  • wu:fj99h01 antibody
  • zgc:56396 antibody

Protein level used designations for MTA1

metastasis associated gene 1 protein , metastasis-associated protein MTA1 , metastasis associated family, member 3 , metastasis-associated protein MTA3

9112 Homo sapiens
447758 Xenopus laevis
429060 Gallus gallus
480450 Canis lupus familiaris
511438 Bos taurus
116870 Mus musculus
64520 Rattus norvegicus
100003254 Danio rerio
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