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Metastasis Associated 1 Family, Member 3 Proteins (MTA3)

Plays a role in maintenance of the normal epithelial architecture through the repression of SNAI1 transcription in a histone deacetylase-dependent manner, and thus the regulation of E-cadherin levels (By similarity). Additionally we are shipping MTA3 Antibodies (56) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat MTA3 MTA3 298763  
MTA3 57504 Q9BTC8
MTA3 116871 Q924K8
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Top MTA3 Proteins at antibodies-online.com

Showing 4 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 19 Days
$785.40
Details

MTA3 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

More Proteins for Metastasis Associated 1 Family, Member 3 (MTA3) Interaction Partners

Human Metastasis Associated 1 Family, Member 3 (MTA3) interaction partners

  1. MTA3 suppress apoptosis of A549 an H157 cells by inhibiting BAX (show BAX Proteins), PARP expression.

  2. This review focuses on the current knowledge about the function and regulation of MTA1 (show MTA1 Proteins) and MTA3 proteins in gynecological cancer, including ovarian, endometrial, and cervical tumors.

  3. MAT3 over-expression in non-small cell lung carcinoma and MAT3 mRNA level is a risk factor for lymph node metastasis and survival.

  4. Using western blotting and luciferase assays, MTA3 was identified as a target of miR (show MLXIP Proteins)-495

  5. MTA3 expression is an independent prognostic factor in patients with gastroesophageal junction adenocarcinoma.

  6. Down-regulation of MTA3 and up-regulation of CGB5 (show CGB Proteins) and Snail (show SNAI1 Proteins) are associated with preeclampsia.

  7. MTA3 is not a useful marker to assess and identify high-risk patients with endometrial adenocarcinomas

  8. The absence of MTA3 leads to aberrant expression of Snail (show SNAI1 Proteins), a master regulator of epithelial to mesenchymal transitions. This results in loss of expression of E-cadherin (show CDH1 Proteins), causing changes in epithelial architecture and invasive growth.

  9. MTA3 does not repress transcription to a significant level and appears to have a diffused pattern of subcellular localization, suggesting a biological role distinct from that of the other two MTA (show DNMT1 Proteins) proteins.

  10. estrogen receptor-alpha (show ESR1 Proteins) regulates metastatic tumor antigen 3 pathway

Mouse (Murine) Metastasis Associated 1 Family, Member 3 (MTA3) interaction partners

  1. Bcl6 (show BCL6 Proteins) middle domain repressor function is required for T follicular helper cell differentiation and utilizes the corepressor MTA3.

  2. Metastasis-associated protein 3 (show HSPB3 Proteins) (MTA3) regulates G2/M progression in proliferating mouse granulosa cells.

  3. These results demonstrate the importance of FOG-2/MTA (show DNMT1 Proteins)/RbAp interactions for FOG-2-mediated transcriptional repression and further define the molecular interactions between the FOG (show APAF1 Proteins) repression motif and the NuRD complex.

MTA3 Protein Profile

Protein Summary

Plays a role in maintenance of the normal epithelial architecture through the repression of SNAI1 transcription in a histone deacetylase-dependent manner, and thus the regulation of E-cadherin levels (By similarity).

Gene names and symbols associated with MTA3

  • metastasis associated 1 family, member 3 (Mta3)
  • metastasis associated 1 family, member 3 (MTA3)
  • metastasis associated 3 (Mta3)
  • 1110002J22Rik protein
  • DKFZp468E247 protein
  • mKIAA1266 protein
  • MTA3 protein

Protein level used designations for MTA3

metastasis associated 1 family, member 3 , metastasis associated 3 , metastasis-associated protein MTA3-like , metastasis associated family, member 3 , metastasis associated gene family, member 3 , metastasis-associated protein MTA3

GENE ID SPECIES
298763 Rattus norvegicus
459183 Pan troglodytes
475740 Canis lupus familiaris
712967 Macaca mulatta
100033381 Monodelphis domestica
100069316 Equus caballus
100171784 Pongo abelii
100408335 Callithrix jacchus
100598554 Nomascus leucogenys
57504 Homo sapiens
421395 Gallus gallus
512854 Bos taurus
100362346 Rattus norvegicus
116871 Mus musculus
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