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Metastasis Associated in Colon Cancer 1 Proteins (MACC1)

MACC1 is a key regulator of the hepatocyte growth factor (HGF\; MIM 142409)-HGF receptor (HGFR, or MET\; MIM 164860) pathway, which is involved in cellular growth, epithelial-mesenchymal transition, angiogenesis, cell motility, invasiveness, and metastasis. Additionally we are shipping MACC1 Antibodies (37) and MACC1 Kits (7) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
MACC1 346389 Q6ZN28
Mouse MACC1 MACC1 238455  
Rat MACC1 MACC1 314539  
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Top MACC1 Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 11 to 13 Days
$862.40
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 9 to 19 Days
$1,030.69
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

MACC1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,

More Proteins for Metastasis Associated in Colon Cancer 1 (MACC1) Interaction Partners

Human Metastasis Associated in Colon Cancer 1 (MACC1) interaction partners

  1. Metastasis-associated in colon cancer-1 may have an important role in tumour development in adenoid cystic carcinoma. Metastasis-associated in colon cancer-1 is a potential biomarker for adenoid cystic carcinoma.

  2. downregulation of MACC1 expression could enhance cisplatin sensitivity and decrease drug resistance in SKOV- 3/DDP (show TIMM8A Proteins) cells.

  3. Our findings suggest that MACC1 protein, as a valuable marker of cervical cancer prognosis, plays an important role in the progression of human cervical cancer cells.

  4. Our results suggest that rs975263 and rs4721888 polymorphisms in MACC1 are associated with the risk of breast cancer susceptibility and may be involved in the progression of breast cancer in Chinese women

  5. Conclude that the ability of proliferation and invasion in T24 cells can be inhibited by RNAi-targeting MACC1.

  6. the expression levels of MACC1 were significantly correlated with the biological processes underlying glioma cell proliferation, invasion and metastasis.

  7. In renal cell carcinoma (show MOK Proteins), positive MACC1 expression was found to significantly correlate with distant metastasis and TNM (show ODZ1 Proteins) stage. patients with higher MACC1 expression had a significantly lower disease-free rate

  8. conclusion, high MACC1 expression may serve as a prognostic biomarker to guide individualized management in clinical practice for digestive system neoplasms.

  9. MACC1 promotes vasculogenic mimicry in gastric cancer by regulating the HGF/c-Met-TWIST1 (show TWIST1 Proteins)/2 signaling pathway.

  10. MACC1 expression predicts survival outcome in colorectal cancer patients.

Mouse (Murine) Metastasis Associated in Colon Cancer 1 (MACC1) interaction partners

  1. Data suggest a critical role for MACC1 in lymphatic dissemination of GC, providing evidence that MACC1 upregulated VEGF-C/VEGF-D secretion to promote lymphangiogenesis via c-Met signaling.

  2. HGF, MACC1 and C-met genes involve into malignant cervical tumors occurrence, development and prognosis, and might become potential molecular target therapy site of cervical cancer

  3. MACC1 has a role in colorectal cancer and can be used for imaging in xenografts

  4. MACC1 will be useful for the identification of poor prognosis subjects with colorectal cancer and is a promising new target for intervention in metastasis formation.

MACC1 Protein Profile

Protein Summary

MACC1 is a key regulator of the hepatocyte growth factor (HGF\; MIM 142409)-HGF receptor (HGFR, or MET\; MIM 164860) pathway, which is involved in cellular growth, epithelial-mesenchymal transition, angiogenesis, cell motility, invasiveness, and metastasis. Expression of MACC1 in colon cancer (MIM 114500) specimens is an independent prognostic indicator for metastasis formation and metastasis-free survival (Stein et al., 2009

Gene names and symbols associated with MACC1

  • metastasis associated in colon cancer 1 (MACC1)
  • metastasis associated in colon cancer 1 (Macc1)
  • 7a5 protein
  • 4732474O15Rik protein
  • Gm267 protein
  • RGD1309838 protein
  • SH3BP4L protein

Protein level used designations for MACC1

SH3 domain-containing protein 7a5 , metastasis-associated in colon cancer protein 1 , putative binding protein 7a5

GENE ID SPECIES
346389 Homo sapiens
238455 Mus musculus
314539 Rattus norvegicus
521867 Bos taurus
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