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MACC1 is a key regulator of the hepatocyte growth factor (HGF\; MIM 142409)-HGF receptor (HGFR, or MET\; MIM 164860) pathway, which is involved in cellular growth, epithelial-mesenchymal transition, angiogenesis, cell motility, invasiveness, and metastasis. Additionally we are shipping MACC1 Kits (10) and MACC1 Proteins (4) and many more products for this protein.
Showing 10 out of 41 products:
Human Polyclonal MACC1 Primary Antibody for IF (p), IHC (p) - ABIN706526
Sun, Li, Dai, Tan, Zhao, Li, Wang: Silence of MACC1 expression by RNA interference inhibits proliferation, invasion and metastasis, and promotes apoptosis in U251 human malignant glioma cells. in Molecular medicine reports 2015
Show all 3 references for 706526
Human Polyclonal MACC1 Primary Antibody for IHC, IHC (p) - ABIN4332277
Ge, Meng, Zhou, Zhang, Ding: Positive MACC1 expression correlates with invasive behaviors and postoperative liver metastasis in colon cancer. in International journal of clinical and experimental medicine 2015
Show all 2 references for 4332277
Human Polyclonal MACC1 Primary Antibody for IHC, IHC (p) - ABIN4332275
Hagemann, Fuchs, Monoranu, Herrmann, Smith, Hohmann, Grabiec, Kessler, Dehghani, Löhr, Ernestus, Vince, Stein: Impact of MACC1 on human malignant glioma progression and patients' unfavorable prognosis. in Neuro-oncology 2013
MACC1 down-regulation suppresses endometrial carcinoma cell proliferation.
SPON2 (show SPON2 Antibodies) is a transcriptional target of the metastasis gene MACC1. SPON2 (show SPON2 Antibodies) induces cell motility in vitro and CRC (show CALR Antibodies) metastasis in mice. In patients, SPON2 (show SPON2 Antibodies) serves as prognostic indicator for CRC (show CALR Antibodies) metastasis and survival, and might represent a promising target for therapeutic approaches.
High MACC1 expression is associated with Angiogenesis and recurrence in Gastric Cancer.
Elevated Orai1 (show ORAI1 Antibodies) and STIM1 (show STIM1 Antibodies) expressions upregulate MACC1 expression to promote tumor cell proliferation, metabolism, migration, and invasion in human gastric cancer.
Data show that metastasis-associated in colon cancer-1 (MACC1) and monocarboxylate transporter 1 (MCT1) are highly expressed in gastric cancer indicating poor prognosis.
A novel role of MACC1 in gastric cancer cell lipogenesis.MACC1 and FASN (show FASN Antibodies) are positively correlated and responsible for the poor prognoses in gastric cancer patients.
MACC1 is more frequently expressed in a poor prognosis phenotype of gastric cancer and acts as a promising prognostic prediction parameter for gastric cancer
Results indicate that Nav 1.7 promotes GC progression through MACC1-mediated upregulation of NHE1 (show SLC9A1 Antibodies).
MACC1 gene (metastasis-associated in colon cancer 1) is upregulated in cancer stem cells both resistant and sensitive to chemotherapy
MACC1 overexpression is associated with gastric cancer.
Data suggest a critical role for MACC1 in lymphatic dissemination of GC, providing evidence that MACC1 upregulated VEGF-C/VEGF-D secretion to promote lymphangiogenesis via c-Met signaling.
HGF, MACC1 and C-met genes involve into malignant cervical tumors occurrence, development and prognosis, and might become potential molecular target therapy site of cervical cancer
MACC1 has a role in colorectal cancer and can be used for imaging in xenografts
MACC1 will be useful for the identification of poor prognosis subjects with colorectal cancer and is a promising new target for intervention in metastasis formation.
MACC1 is a key regulator of the hepatocyte growth factor (HGF\; MIM 142409)-HGF receptor (HGFR, or MET\; MIM 164860) pathway, which is involved in cellular growth, epithelial-mesenchymal transition, angiogenesis, cell motility, invasiveness, and metastasis. Expression of MACC1 in colon cancer (MIM 114500) specimens is an independent prognostic indicator for metastasis formation and metastasis-free survival (Stein et al., 2009
SH3 domain-containing protein 7a5
, metastasis-associated in colon cancer protein 1
, putative binding protein 7a5