anti-Metastasis Associated in Colon Cancer 1 (MACC1) Antibodies

MACC1 is a key regulator of the hepatocyte growth factor (HGF\; MIM 142409)-HGF receptor (HGFR, or MET\; MIM 164860) pathway, which is involved in cellular growth, epithelial-mesenchymal transition, angiogenesis, cell motility, invasiveness, and metastasis. Additionally we are shipping MACC1 Kits (10) and MACC1 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
MACC1 346389 Q6ZN28
MACC1 238455  
MACC1 314539  
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Top anti-MACC1 Antibodies at antibodies-online.com

Showing 10 out of 40 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB Western blot analysis of MACC1 expression in HEK293T (A), H9C2 (B) whole cell lysates. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human stomach tissue labeled with Anti-MACC1Polyclonal Antibody, Unconjugated (ABIN706526) followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded human gastric carcinoma labeled with Anti-MACC1 Polyclonal Antibody, Unconjugated (ABIN706526) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$307.45
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB   0.1 mg Log in to see 10 to 12 Days
$375.38
Details
Human Rabbit Un-conjugated IHC, IHC (p), SimWes Simple Western: MACC1 Antibody [NBP1-89352] - Simple Western lane view shows a specific band for MACC1 in 0.2 mg/ml of RT-4 lysate. This experiment was performed under reducing conditions using the 12-230 kDa separation system. Immunohistochemistry-Paraffin: MACC1 Antibody [NBP1-89352] - Staining of human endometrium shows strong cytoplasmic positivity in glandular cells. 0.1 mL Log in to see 10 to 13 Days
$439.69
Details
Human Rabbit Un-conjugated IHC, IHC (p), WB Western Blot: MACC1 Antibody [NBP1-89351] - Lane 1: Marker [kDa] 250, 130, 100, 70, 55, 35, 25, 15, 10.Lane 2: Human cell line A-431 Immunohistochemistry-Paraffin: MACC1 Antibody [NBP1-89351] - Staining of human duodenum shows cytoplasmic positivity in glandular cells. 0.1 mL Log in to see 10 to 13 Days
$439.69
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL Log in to see 16 Days
$175.80
Details
Human Rabbit Cy3 IF (p)   100 μL Log in to see 14 to 21 Days
$417.45
Details
Human Rabbit Cy5 IF (p)   100 μL Log in to see 14 to 21 Days
$417.45
Details
Human Rabbit Cy7 IF (p)   100 μL Log in to see 14 to 21 Days
$417.45
Details
Human Rabbit Cy5.5 IF (p)   100 μL Log in to see 14 to 21 Days
$417.45
Details

MACC1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-MACC1 Antibodies

  1. Human Polyclonal MACC1 Primary Antibody for IF (p), IHC (p) - ABIN706526 : Sun, Li, Dai, Tan, Zhao, Li, Wang: Silence of MACC1 expression by RNA interference inhibits proliferation, invasion and metastasis, and promotes apoptosis in U251 human malignant glioma cells. in Molecular medicine reports 2015 (PubMed)
    Show all 3 Pubmed References

  2. Human Polyclonal MACC1 Primary Antibody for IHC, IHC (p) - ABIN4332277 : Ge, Meng, Zhou, Zhang, Ding: Positive MACC1 expression correlates with invasive behaviors and postoperative liver metastasis in colon cancer. in International journal of clinical and experimental medicine 2015 (PubMed)
    Show all 2 Pubmed References

  3. Human Polyclonal MACC1 Primary Antibody for ELISA, IHC - ABIN5582886 : Liu, Pan, Guo, Wu, Guo, Peng, Wu, Zuo: A new mechanism of trastuzumab resistance in gastric cancer: MACC1 promotes the Warburg effect via activation of the PI3K/AKT signaling pathway. in Journal of hematology & oncology 2016 (PubMed)

  4. Human Polyclonal MACC1 Primary Antibody for IHC, IHC (p) - ABIN4332275 : Hagemann, Fuchs, Monoranu, Herrmann, Smith, Hohmann, Grabiec, Kessler, Dehghani, Löhr, Ernestus, Vince, Stein: Impact of MACC1 on human malignant glioma progression and patients' unfavorable prognosis. in Neuro-oncology 2013 (PubMed)

More Antibodies against MACC1 Interaction Partners

Human Metastasis Associated in Colon Cancer 1 (MACC1) interaction partners

  1. Metastasis-associated in colon cancer 1 is expressed at early stages of colorectal oncogenesis within the affected colonic tissue in colorectal cancer patient cohort.

  2. MACC1 is a key driver and prognostic biomarker for cancer progression and metastasis in a large variety of solid tumor types, particularly colorectal cancer (CRC (show CALR Antibodies)). Data suggest that some small molecules with antineoplastic activity inhibit MACC1 transcription in CRC (show CALR Antibodies) and prevent liver metastasis in CRC (show CALR Antibodies); lovastatin and rottlerin are the antineoplastic agents used here.

  3. MACC1 regulates Fas (show FAS Antibodies) mediated apoptosis through STAT1 (show STAT1 Antibodies)/3 - Mcl-1 (show MCL1 Antibodies) signaling in solid cancers.

  4. High expression of MACC1 is associated with non-small cell lung cancer.

  5. MACC1 down-regulation suppresses endometrial carcinoma cell proliferation.

  6. SPON2 (show SPON2 Antibodies) is a transcriptional target of the metastasis gene MACC1. SPON2 (show SPON2 Antibodies) induces cell motility in vitro and CRC (show CALR Antibodies) metastasis in mice. In patients, SPON2 (show SPON2 Antibodies) serves as prognostic indicator for CRC (show CALR Antibodies) metastasis and survival, and might represent a promising target for therapeutic approaches.

  7. High MACC1 expression is associated with Angiogenesis and recurrence in Gastric Cancer.

  8. Elevated Orai1 (show ORAI1 Antibodies) and STIM1 (show STIM1 Antibodies) expressions upregulate MACC1 expression to promote tumor cell proliferation, metabolism, migration, and invasion in human gastric cancer.

  9. Data show that metastasis-associated in colon cancer-1 (MACC1) and monocarboxylate transporter 1 (MCT1) are highly expressed in gastric cancer indicating poor prognosis.

  10. A novel role of MACC1 in gastric cancer cell lipogenesis.MACC1 and FASN (show FASN Antibodies) are positively correlated and responsible for the poor prognoses in gastric cancer patients.

Mouse (Murine) Metastasis Associated in Colon Cancer 1 (MACC1) interaction partners

  1. Data suggest a critical role for MACC1 in lymphatic dissemination of GC, providing evidence that MACC1 upregulated VEGF-C/VEGF-D secretion to promote lymphangiogenesis via c-Met signaling.

  2. HGF, MACC1 and C-met genes involve into malignant cervical tumors occurrence, development and prognosis, and might become potential molecular target therapy site of cervical cancer

  3. MACC1 has a role in colorectal cancer and can be used for imaging in xenografts

  4. MACC1 will be useful for the identification of poor prognosis subjects with colorectal cancer and is a promising new target for intervention in metastasis formation.

MACC1 Antigen Profile

Protein Summary

MACC1 is a key regulator of the hepatocyte growth factor (HGF\; MIM 142409)-HGF receptor (HGFR, or MET\; MIM 164860) pathway, which is involved in cellular growth, epithelial-mesenchymal transition, angiogenesis, cell motility, invasiveness, and metastasis. Expression of MACC1 in colon cancer (MIM 114500) specimens is an independent prognostic indicator for metastasis formation and metastasis-free survival (Stein et al., 2009

Gene names and symbols associated with MACC1

  • metastasis associated in colon cancer 1 (MACC1) antibody
  • metastasis associated in colon cancer 1 (Macc1) antibody
  • 7a5 antibody
  • 4732474O15Rik antibody
  • Gm267 antibody
  • RGD1309838 antibody
  • SH3BP4L antibody

Protein level used designations for MACC1

SH3 domain-containing protein 7a5 , metastasis-associated in colon cancer protein 1 , putative binding protein 7a5

GENE ID SPECIES
346389 Homo sapiens
238455 Mus musculus
314539 Rattus norvegicus
521867 Bos taurus
Selected quality suppliers for anti-MACC1 (MACC1) Antibodies
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