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May be related to cancer progression or tumor metastasis in a variety of organ sites, most likely through an interaction with the actin cytoskeleton.. Additionally we are shipping MTSS1 Proteins (4) and many more products for this protein.
Showing 10 out of 68 products:
Human Monoclonal MTSS1 Primary Antibody for IHC (p), ELISA - ABIN3013366
Parr, Jiang: Metastasis suppressor 1 (MTSS1) demonstrates prognostic value and anti-metastatic properties in breast cancer. in European journal of cancer (Oxford, England : 1990) 2009
Show all 5 references for ABIN3013366
Human Polyclonal MTSS1 Primary Antibody for IF (p), IHC (p) - ABIN762056
Chen, Chen, Zhao, Yang, Imran, Xing: Microarray analyses reveal liver metastasis-related genes in metastatic colorectal cancer cell model. in Journal of cancer research and clinical oncology 2013
Down-regulation of MTSS1 expression is associated with lymph node metastasis in Pancreatic Cancer.
Low expression of Mtss1 is associated with Chronic myeloid leukemia (show BCL11A Antibodies).
MTSS1 plays an essential inhibitory role in the development and progression of ovarian cancers
human breast tumors data sets the MTSS1/p63 (show RPE65 Antibodies) co-expression is a negative prognostic factor on patient survival, suggesting that the MTSS1/p63 (show RPE65 Antibodies) axis might be functionally important to regulate breast tumor progression
our findings suggest that MTSS1 might have a context-dependent function and could act as a tumor suppressor, which is pharmacologically targetable in AML (show RUNX1 Antibodies) patients.
EGF (show EGF Antibodies) induces microRNAs that target suppressors of cell migration: miR (show MLXIP Antibodies)-15b targets MTSS1 in breast cancer.
These results implicate that the role of MTSS1 suppresses cell migration and invasion by inhibiting expression of CTTN (show CTTN Antibodies) and as a prognosis biomarker in Glioblastomas
Data shows that MTSS1 is highly expressed in non-small-cell lung carcinomas compared with non-neoplastic lung tissues and may serve as an independent prognostic factor.
The absence of MIM led to PTPdelta-mediated activation of SRC (show SRC Antibodies).
Study provides a novel molecular mechanism for the negative regulation of MTSS1 by beta-TRCP (show BTRC Antibodies) in cancer cells.
Identify the inverse-BAR (I-BAR) protein MIM/MTSS1 as a nucleator of dendritic spines. MIM accumulated to future spine initiation sites in a PIP2-dependent manner and deformed the plasma membrane outward into a proto-protrusion via its I-BAR domain.
The data demonstrated for the first time an important role for missing-in-metastasis protein in B-cell development. There was a predisposition of missing-in-metastasis-null mice to develop diffuse large B lymphomas.
MTSS1 might be involved in shaping neuronal membranes in vivo.
endogenous MIM protein regulates globally the cell architecture and endocytosis that ultimately influence a variety of cellular behaviors, including cell polarity, motility, receptor signaling and membrane ruffling
MTSS1 promotes actin assembly at intercellular junctions and is required for integrity of kidney epithelia.
Results suggest that MIM promotes ciliogenesis by antagonizing Src (show SRC Antibodies)-dependent phosphorylation of Cortactin (show CTTN Antibodies) and describe a mechanism linking regulation of the actin cytoskeleton with ciliogenesis and Shh (show SHH Antibodies) signaling during tissue regeneration.
tissue-specific regulator of cytoskeletal dynamics that interacts with ATP-actin monomers through its C-terminal WH2 domain
Hedgehog (show SHH Antibodies)-responsive gene MIM cooperates with receptor protein tyrosine phosphatase (show PTPRT Antibodies)-delta (show PTPRD Antibodies) to induce cytoskeletal remodeling.
Mtss1 represents a novel signaling pathway from PDGF (show PDGFA Antibodies) receptor to the actin cytoskeleton via Src (show SRC Antibodies)-related kinases.
The crystal structures of MIM's IMD and that of its WH2 bound to actin was determined.
morphogenetic pathway involving Daam1 (show DAAM1 Antibodies) and MIM that transduces non-canonical Wnt (show WNT2 Antibodies) signaling for the cytoskeletal changes and membrane dynamics required for vertebrate neural tube closure
May be related to cancer progression or tumor metastasis in a variety of organ sites, most likely through an interaction with the actin cytoskeleton.
metastasis suppressor 1
, metastasis suppressor protein 1
, metastasis suppressor protein 1-like
, metastasis suppressor YGL-1
, missing in metastasis protein
, actin monomer-binding protein