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Metastasis Suppressor 1 Proteins (MTSS1)

May be related to cancer progression or tumor metastasis in a variety of organ sites, most likely through an interaction with the actin cytoskeleton.. Additionally we are shipping MTSS1 Antibodies (36) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
MTSS1 9788 O43312
MTSS1 211401 Q8R1S4
Rat MTSS1 MTSS1 362918  
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Top MTSS1 Proteins at

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag,MBP tag 50 μg Log in to see 16 Days
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific pu... 1 mg Log in to see 39 to 44 Days
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific pu... 1 mg Log in to see 39 to 44 Days
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days

MTSS1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
, ,
Mouse (Murine)

Top referenced MTSS1 Proteins

  1. Human MTSS1 Protein expressed in Escherichia coli (E. coli) - ABIN2005419 : Glassmann, Molly, Surchev, Nazwar, Holst, Hartmann, Baader, Oberdick, Pietsch, Schilling: Developmental expression and differentiation-related neuron-specific splicing of metastasis suppressor 1 (Mtss1) in normal and transformed cerebellar cells. in BMC developmental biology 2008 (PubMed)
    Show all 2 references for ABIN2005419

More Proteins for Metastasis Suppressor 1 (MTSS1) Interaction Partners

Human Metastasis Suppressor 1 (MTSS1) interaction partners

  1. Low expression of Mtss1 is associated with Chronic myeloid leukemia (show BCL11A Proteins).

  2. MTSS1 plays an essential inhibitory role in the development and progression of ovarian cancers

  3. human breast tumors data sets the MTSS1/p63 (show RPE65 Proteins) co-expression is a negative prognostic factor on patient survival, suggesting that the MTSS1/p63 (show RPE65 Proteins) axis might be functionally important to regulate breast tumor progression

  4. our findings suggest that MTSS1 might have a context-dependent function and could act as a tumor suppressor, which is pharmacologically targetable in AML (show RUNX1 Proteins) patients.

  5. EGF (show EGF Proteins) induces microRNAs that target suppressors of cell migration: miR (show MLXIP Proteins)-15b targets MTSS1 in breast cancer.

  6. These results implicate that the role of MTSS1 suppresses cell migration and invasion by inhibiting expression of CTTN (show CTTN Proteins) and as a prognosis biomarker in Glioblastomas

  7. Data shows that MTSS1 is highly expressed in non-small-cell lung carcinomas compared with non-neoplastic lung tissues and may serve as an independent prognostic factor.

  8. The absence of MIM led to PTPdelta-mediated activation of SRC (show SRC Proteins).

  9. Study provides a novel molecular mechanism for the negative regulation of MTSS1 by beta-TRCP (show BTRC Proteins) in cancer cells.

  10. MTSS1 expression was analyzed in normal and cancerous tissue specimens from Chinese patients with Hilar cholangiocarcinoma.

Mouse (Murine) Metastasis Suppressor 1 (MTSS1) interaction partners

  1. Identify the inverse-BAR (I-BAR) protein MIM/MTSS1 as a nucleator of dendritic spines. MIM accumulated to future spine initiation sites in a PIP2-dependent manner and deformed the plasma membrane outward into a proto-protrusion via its I-BAR domain.

  2. The data demonstrated for the first time an important role for missing-in-metastasis protein in B-cell development. There was a predisposition of missing-in-metastasis-null mice to develop diffuse large B lymphomas.

  3. MTSS1 might be involved in shaping neuronal membranes in vivo.

  4. endogenous MIM protein regulates globally the cell architecture and endocytosis that ultimately influence a variety of cellular behaviors, including cell polarity, motility, receptor signaling and membrane ruffling

  5. MTSS1 promotes actin assembly at intercellular junctions and is required for integrity of kidney epithelia.

  6. Results suggest that MIM promotes ciliogenesis by antagonizing Src (show SRC Proteins)-dependent phosphorylation of Cortactin (show CTTN Proteins) and describe a mechanism linking regulation of the actin cytoskeleton with ciliogenesis and Shh (show SHH Proteins) signaling during tissue regeneration.

  7. tissue-specific regulator of cytoskeletal dynamics that interacts with ATP-actin monomers through its C-terminal WH2 domain

  8. Hedgehog (show SHH Proteins)-responsive gene MIM cooperates with receptor protein tyrosine phosphatase (show PTPRT Proteins)-delta (show PTPRD Proteins) to induce cytoskeletal remodeling.

  9. Mtss1 represents a novel signaling pathway from PDGF (show PDGFA Proteins) receptor to the actin cytoskeleton via Src (show SRC Proteins)-related kinases.

  10. The crystal structures of MIM's IMD and that of its WH2 bound to actin was determined.

Xenopus laevis Metastasis Suppressor 1 (MTSS1) interaction partners

  1. morphogenetic pathway involving Daam1 (show DAAM1 Proteins) and MIM that transduces non-canonical Wnt (show WNT2 Proteins) signaling for the cytoskeletal changes and membrane dynamics required for vertebrate neural tube closure

MTSS1 Protein Profile

Protein Summary

May be related to cancer progression or tumor metastasis in a variety of organ sites, most likely through an interaction with the actin cytoskeleton.

Gene names and symbols associated with MTSS1

  • metastasis suppressor 1 (MTSS1)
  • metastasis suppressor 1 (mtss1)
  • metastasis suppressor 1 (Mtss1)
  • metastasis suppressor 1, gene 2 (mtss1.2)
  • 2310003N14Rik protein
  • BC024131 protein
  • D130001D01Rik protein
  • mim protein
  • mima protein
  • mimb protein
  • mKIAA0429 protein
  • mtss1 protein

Protein level used designations for MTSS1

metastasis suppressor 1 , metastasis suppressor protein 1 , metastasis suppressor protein 1-like , metastasis suppressor YGL-1 , missing in metastasis protein , actin monomer-binding protein

711465 Macaca mulatta
100080535 Ornithorhynchus anatinus
100157797 Sus scrofa
100174755 Pongo abelii
100355361 Oryctolagus cuniculus
100410891 Callithrix jacchus
100467780 Ailuropoda melanoleuca
100547471 Meleagris gallopavo
100559325 Anolis carolinensis
100582996 Nomascus leucogenys
464381 Pan troglodytes
9788 Homo sapiens
482037 Canis lupus familiaris
100067482 Equus caballus
523498 Bos taurus
211401 Mus musculus
362918 Rattus norvegicus
420336 Gallus gallus
447209 Xenopus laevis
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