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The protein encoded by MAT2A catalyzes the production of S-adenosylmethionine (AdoMet) from methionine and ATP. Additionally we are shipping Methionine Adenosyltransferase II, alpha Proteins (16) and Methionine Adenosyltransferase II, alpha Kits (12) and many more products for this protein.
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Human Monoclonal MAT2A Primary Antibody for EIA, IHC (p) - ABIN356234
Ramani, Yang, Xia, Ara, Mato, Lu: Leptin's mitogenic effect in human liver cancer cells requires induction of both methionine adenosyltransferase 2A and 2beta. in Hepatology (Baltimore, Md.) 2008
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acet (show EP300 Antibodies)ylation decreased in hepatocellular cancer
The data presented here support the conclusion that rare genetic variants in MAT2A predispose individuals to thoracic aortic disease.
Results suggest that MAT2A is downregulated in cancer tissues of renal cell carcinomas patients and has function of tumor suppressor though repressing the expression of heme oxygenase-1 (show HMOX1 Antibodies).
Liver-specific isoenzyme MAT1A (show MAT1A Antibodies) is genetically linked with an inborn metabolic disorder of hypermethioninemia, as well as a ubiquitously expressed isoenzyme MAT2A, whose enzymatic activity is regulated by an associated subunit MAT2B (show MAT2B Antibodies).
Differential gene expression of BACE1 (show BACE Antibodies) and PSEN1 (show PSEN1 Antibodies) in the knockdown cells, which is possibly a consequence of MAT2A deregulation and may indicate a self regulatory mechanism.
we found for the first time a post-transcriptional regulation of MAT1A (show MAT1A Antibodies) and MAT2A by AUF1 (show HNRNPD Antibodies) and HuR (show ELAVL1 Antibodies) in hepatocellular carcinoma.
hypoxia-induced MAT2A expression is HIF-1alpha (show HIF1A Antibodies) dependent
Insulin-like growth factor 1 (IGF1 (show IGF1 Antibodies)) activates methionine adenosyltransferase 2A MAT2A) transcription by both known and novel pathways in colon cancer cells.
X protein of hepatitis B virus inhibits apoptosis in hepatoma cells through enhancing the methionine adenosyltransferase 2A gene expression and reducing S-adenosylmethionine production
Methionine adenosyltransferase II serves as a transcriptional corepressor of Maf (show MAF Antibodies) oncoprotein
P300 (show NOTCH1 Antibodies) acetylates MAT IIalpha at lysine residue 81 and destabilizes MAT IIalpha by promoting its ubiquitylation and subsequent proteasomal degradation.
MATIIalpha represses the expression of cyclooxygenase 2 (COX-2 (show PTGS2 Antibodies)), encoded by Ptgs2 (show PTGS2 Antibodies), by specifically interacting with histone H3K9 methyltransferase SETDB1 (show SETDB1 Antibodies).
MAT2A and MAT2beta (show MAT2B Antibodies) genes are induced during hepatic stellate cell activation
up-regulation of MAT2A also provides a growth advantage and s-adenosylmethionine and methylthioadenosine can block mitogenic signaling in colon cancer cells.
The protein encoded by this gene catalyzes the production of S-adenosylmethionine (AdoMet) from methionine and ATP. AdoMet is the key methyl donor in cellular processes.
methionine adenosyltransferase II, alpha
, S-adenosylmethionine synthetase isoform type-2-like
, MAT 2
, S-adenosylmethionine synthase isoform type-2
, adoMet synthase 2
, adoMet synthetase 2
, methionine adenosyltransferase 2
, S-adenosylmethionine synthetase isoform type-2
, non-hepatic-type S-adenosylmethionine synthetase