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anti-Methionine Adenosyltransferase II, alpha (MAT2A) Antibodies

The protein encoded by MAT2A catalyzes the production of S-adenosylmethionine (AdoMet) from methionine and ATP. Additionally we are shipping Methionine Adenosyltransferase II, alpha Proteins (16) and Methionine Adenosyltransferase II, alpha Kits (12) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
MAT2A 4144 P31153
MAT2A 232087 Q3THS6
MAT2A 171347 P18298
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Top anti-Methionine Adenosyltransferase II, alpha Antibodies at antibodies-online.com

Showing 10 out of 84 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse Un-conjugated EIA, IHC (p), WB 0.1 mL Log in to see 6 to 8 Days
$412.50
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-MAT2A  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500  Positive Control: Hela cell lysate  MAT2A is strongly supported by BioGPS gene expression data to be expressed in Human HeLa cells 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated ICC, IF, WB Western Blot: MAT2A Antibody [ABIN4100438] - Total protein from HeLa and HepG2 cells and Human and Mouse Kidney was separated on a 12% gel by SDS-PAGE, transferred to PVDF membrane and blocked in 5% non-fat milk in TBST. The membrane was probed with 2.0 ug/ml anti-MAT2A in 1% non-fat milk in TBST and detected with an anti-rabbit HRP secondary antibody using chemiluminescence. Immunocytochemistry/Immunofluorescence: MAT2A Antibody [ABIN4100438] - MAT2A antibody was tested in HepG2 cells with Dylight 488 (green). Nuclei and alpha-tubulin were counterstained with DAPI (blue) and Dylight 550 (red). 0.1 mL Log in to see 5 to 7 Days
$391.13
Details
Human Rabbit Un-conjugated WB MAT2A Antibody (N-term)  western blot analysis in Ramos cell line lysates (35ug/lane).This demonstrates the MAT2A antibody detected the MAT2A protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated IHC (p), ELISA, WB Human Testis (formalin-fixed, paraffin-embedded) stained with MAT2A antibody ABIN364446 at 10 ug/ml followed by biotinylated anti-mouse IgG secondary antibody ABIN481714, alkaline phosphatase-streptavidin and chromogen. Human Kidney (formalin-fixed, paraffin-embedded) stained with MAT2A antibody ABIN364446 at 10 ug/ml followed by biotinylated anti-mouse IgG secondary antibody ABIN481714, alkaline phosphatase-streptavidin and chromogen. 50 μL Log in to see 8 to 10 Days
$451.00
Details
Cow Rabbit HRP WB   0.1 mL Log in to see 5 to 7 Days
$427.88
Details
Human Mouse Un-conjugated IHC, ELISA, WB 0.05 mL Log in to see 2 to 3 Days
$515.63
Details
Human Chicken Un-conjugated WB 0.05 mg Log in to see 2 to 3 Days
$446.88
Details
Human Rabbit APC ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Mouse Un-conjugated IHC, ELISA, WB Paraffin embedded sections of human colon canitrocelluloseer tissue were initrocelluloseubated with anti-human MAT2A (1:50) for 2 hours at room temperature. Antigen retrieval was performed in 0.1M sodium citrate buffer and detected using Diaminobenzidine (DAB) Cell lysates of HepG2 (20 ug) were resolved by SDS-PAGE, transferred to nitrocellulose membrane and probed with anti-human MAT2A (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. 100 μL Log in to see 3 to 4 Days
$376.79
Details

MAT2A Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Methionine Adenosyltransferase II, alpha Antibodies

  1. Cow (Bovine) Polyclonal MAT2A Primary Antibody for ICC, IF - ABIN410043 : Ramani, Tomasi: Transcriptional regulation of methionine adenosyltransferase 2A by peroxisome proliferator-activated receptors in rat hepatic stellate cells. in Hepatology (Baltimore, Md.) 2012 (PubMed)
    Show all 3 references for ABIN410043

  2. Human Monoclonal MAT2A Primary Antibody for EIA, IHC (p) - ABIN356234 : Ramani, Yang, Xia, Ara, Mato, Lu: Leptin's mitogenic effect in human liver cancer cells requires induction of both methionine adenosyltransferase 2A and 2beta. in Hepatology (Baltimore, Md.) 2008 (PubMed)
    Show all 2 references for ABIN356234

  3. Cow (Bovine) Polyclonal MAT2A Primary Antibody for WB - ABIN410047 : Ramani, Donoyan, Tomasi, Park: Role of methionine adenosyltransferase α2 and β phosphorylation and stabilization in human hepatic stellate cell trans-differentiation. in Journal of cellular physiology 2015 (PubMed)

More Antibodies against Methionine Adenosyltransferase II, alpha Interaction Partners

Human Methionine Adenosyltransferase II, alpha (MAT2A) interaction partners

  1. acet (show EP300 Antibodies)ylation decreased in hepatocellular cancer

  2. The data presented here support the conclusion that rare genetic variants in MAT2A predispose individuals to thoracic aortic disease.

  3. Results suggest that MAT2A is downregulated in cancer tissues of renal cell carcinomas patients and has function of tumor suppressor though repressing the expression of heme oxygenase-1 (show HMOX1 Antibodies).

  4. Liver-specific isoenzyme MAT1A (show MAT1A Antibodies) is genetically linked with an inborn metabolic disorder of hypermethioninemia, as well as a ubiquitously expressed isoenzyme MAT2A, whose enzymatic activity is regulated by an associated subunit MAT2B (show MAT2B Antibodies).

  5. Differential gene expression of BACE1 (show BACE Antibodies) and PSEN1 (show PSEN1 Antibodies) in the knockdown cells, which is possibly a consequence of MAT2A deregulation and may indicate a self regulatory mechanism.

  6. we found for the first time a post-transcriptional regulation of MAT1A (show MAT1A Antibodies) and MAT2A by AUF1 (show HNRNPD Antibodies) and HuR (show ELAVL1 Antibodies) in hepatocellular carcinoma.

  7. hypoxia-induced MAT2A expression is HIF-1alpha (show HIF1A Antibodies) dependent

  8. Insulin-like growth factor 1 (IGF1 (show IGF1 Antibodies)) activates methionine adenosyltransferase 2A MAT2A) transcription by both known and novel pathways in colon cancer cells.

  9. X protein of hepatitis B virus inhibits apoptosis in hepatoma cells through enhancing the methionine adenosyltransferase 2A gene expression and reducing S-adenosylmethionine production

  10. Methionine adenosyltransferase II serves as a transcriptional corepressor of Maf (show MAF Antibodies) oncoprotein

Mouse (Murine) Methionine Adenosyltransferase II, alpha (MAT2A) interaction partners

  1. P300 (show NOTCH1 Antibodies) acetylates MAT IIalpha at lysine residue 81 and destabilizes MAT IIalpha by promoting its ubiquitylation and subsequent proteasomal degradation.

  2. MATIIalpha represses the expression of cyclooxygenase 2 (COX-2 (show PTGS2 Antibodies)), encoded by Ptgs2 (show PTGS2 Antibodies), by specifically interacting with histone H3K9 methyltransferase SETDB1 (show SETDB1 Antibodies).

  3. Methionine adenosyltransferase II serves as a transcriptional corepressor of Maf (show MAF Antibodies) oncoprotein

  4. MAT2A and MAT2beta (show MAT2B Antibodies) genes are induced during hepatic stellate cell activation

  5. up-regulation of MAT2A also provides a growth advantage and s-adenosylmethionine and methylthioadenosine can block mitogenic signaling in colon cancer cells.

Methionine Adenosyltransferase II, alpha (MAT2A) Antigen Profile

Protein Summary

The protein encoded by this gene catalyzes the production of S-adenosylmethionine (AdoMet) from methionine and ATP. AdoMet is the key methyl donor in cellular processes.

Gene names and symbols associated with MAT2A

  • methionine adenosyltransferase II, alpha (mat2a) antibody
  • methionine adenosyltransferase II, alpha (MAT2A) antibody
  • methionine adenosyltransferase II, alpha (Mat2a) antibody
  • methionine adenosyltransferase II, alpha a (mat2aa) antibody
  • D630045P18Rik antibody
  • fd12a12 antibody
  • m(2)21ab antibody
  • mat2a antibody
  • MATA2 antibody
  • MATII antibody
  • MGC76253 antibody
  • MGC79598 antibody
  • Sams2 antibody
  • si:ch73-340n8.1 antibody
  • wu:fb95e01 antibody
  • wu:fd12a12 antibody

Protein level used designations for MAT2A

methionine adenosyltransferase II, alpha , S-adenosylmethionine synthetase isoform type-2-like , MAT 2 , MAT-II , S-adenosylmethionine synthase isoform type-2 , adoMet synthase 2 , adoMet synthetase 2 , methionine adenosyltransferase 2 , S-adenosylmethionine synthetase isoform type-2 , non-hepatic-type S-adenosylmethionine synthetase

GENE ID SPECIES
379867 Xenopus laevis
395032 Xenopus (Silurana) tropicalis
459363 Pan troglodytes
475770 Canis lupus familiaris
695362 Macaca mulatta
100339456 Oryctolagus cuniculus
100412649 Callithrix jacchus
4144 Homo sapiens
100173772 Pongo abelii
232087 Mus musculus
171347 Rattus norvegicus
100312974 Sus scrofa
527403 Bos taurus
323329 Danio rerio
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