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Methionine Adenosyltransferase II, alpha Proteins (MAT2A)

The protein encoded by MAT2A catalyzes the production of S-adenosylmethionine (AdoMet) from methionine and ATP. Additionally we are shipping Methionine Adenosyltransferase II, alpha Antibodies (80) and Methionine Adenosyltransferase II, alpha Kits (12) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
MAT2A 4144 P31153
MAT2A 232087 Q3THS6
MAT2A 171347 P18298
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Top Methionine Adenosyltransferase II, alpha Proteins at antibodies-online.com

Showing 10 out of 16 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human Un-conjugated 0.1 mg Log in to see 2 to 3 Days
$515.63
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 7 to 8 Days
$319.00
Details
HOST_Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$732.60
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,091.00
Details
Yeast Pongo abelii His tag   1 mg Log in to see 56 to 66 Days
$3,091.00
Details
Yeast Macaca fascicularis His tag   1 mg Log in to see 56 to 66 Days
$3,091.00
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 3 to 4 Days
$364.64
Details

MAT2A Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine)

Rat (Rattus)

Top referenced Methionine Adenosyltransferase II, alpha Proteins

  1. Human MAT2A Protein expressed in Escherichia coli (E. coli) - ABIN667082 : Chen, Xia, Lin, Yang, Kuhlenkamp, Li, Sodir, Chen, Josef-Lenz, Laird, Clarke, Mato, Lu: Role of methionine adenosyltransferase 2A and S-adenosylmethionine in mitogen-induced growth of human colon cancer cells. in Gastroenterology 2007 (PubMed)
    Show all 2 references for ABIN667082

More Proteins for Methionine Adenosyltransferase II, alpha (MAT2A) Interaction Partners

Human Methionine Adenosyltransferase II, alpha (MAT2A) interaction partners

  1. acet (show EP300 Proteins)ylation decreased in hepatocellular cancer

  2. The data presented here support the conclusion that rare genetic variants in MAT2A predispose individuals to thoracic aortic disease.

  3. Results suggest that MAT2A is downregulated in cancer tissues of renal cell carcinomas patients and has function of tumor suppressor though repressing the expression of heme oxygenase-1 (show HMOX1 Proteins).

  4. Liver-specific isoenzyme MAT1A (show MAT1A Proteins) is genetically linked with an inborn metabolic disorder of hypermethioninemia, as well as a ubiquitously expressed isoenzyme MAT2A, whose enzymatic activity is regulated by an associated subunit MAT2B (show MAT2B Proteins).

  5. Differential gene expression of BACE1 (show BACE Proteins) and PSEN1 (show PSEN1 Proteins) in the knockdown cells, which is possibly a consequence of MAT2A deregulation and may indicate a self regulatory mechanism.

  6. we found for the first time a post-transcriptional regulation of MAT1A (show MAT1A Proteins) and MAT2A by AUF1 (show HNRNPD Proteins) and HuR (show ELAVL1 Proteins) in hepatocellular carcinoma.

  7. hypoxia-induced MAT2A expression is HIF-1alpha (show HIF1A Proteins) dependent

  8. Insulin-like growth factor 1 (IGF1 (show IGF1 Proteins)) activates methionine adenosyltransferase 2A MAT2A) transcription by both known and novel pathways in colon cancer cells.

  9. X protein of hepatitis B virus inhibits apoptosis in hepatoma cells through enhancing the methionine adenosyltransferase 2A gene expression and reducing S-adenosylmethionine production

  10. Methionine adenosyltransferase II serves as a transcriptional corepressor of Maf (show MAF Proteins) oncoprotein

Mouse (Murine) Methionine Adenosyltransferase II, alpha (MAT2A) interaction partners

  1. P300 (show NOTCH1 Proteins) acetylates MAT IIalpha at lysine residue 81 and destabilizes MAT IIalpha by promoting its ubiquitylation and subsequent proteasomal degradation.

  2. MATIIalpha represses the expression of cyclooxygenase 2 (COX-2 (show PTGS2 Proteins)), encoded by Ptgs2 (show PTGS2 Proteins), by specifically interacting with histone H3K9 methyltransferase SETDB1 (show SETDB1 Proteins).

  3. Methionine adenosyltransferase II serves as a transcriptional corepressor of Maf (show MAF Proteins) oncoprotein

  4. MAT2A and MAT2beta (show MAT2B Proteins) genes are induced during hepatic stellate cell activation

  5. up-regulation of MAT2A also provides a growth advantage and s-adenosylmethionine and methylthioadenosine can block mitogenic signaling in colon cancer cells.

Methionine Adenosyltransferase II, alpha (MAT2A) Protein Profile

Protein Summary

The protein encoded by this gene catalyzes the production of S-adenosylmethionine (AdoMet) from methionine and ATP. AdoMet is the key methyl donor in cellular processes.

Gene names and symbols associated with MAT2A

  • methionine adenosyltransferase II, alpha (mat2a)
  • methionine adenosyltransferase II, alpha (MAT2A)
  • methionine adenosyltransferase II, alpha (Mat2a)
  • methionine adenosyltransferase II, alpha a (mat2aa)
  • D630045P18Rik protein
  • fd12a12 protein
  • m(2)21ab protein
  • mat2a protein
  • MATA2 protein
  • MATII protein
  • MGC76253 protein
  • MGC79598 protein
  • Sams2 protein
  • si:ch73-340n8.1 protein
  • wu:fb95e01 protein
  • wu:fd12a12 protein

Protein level used designations for MAT2A

methionine adenosyltransferase II, alpha , S-adenosylmethionine synthetase isoform type-2-like , MAT 2 , MAT-II , S-adenosylmethionine synthase isoform type-2 , adoMet synthase 2 , adoMet synthetase 2 , methionine adenosyltransferase 2 , S-adenosylmethionine synthetase isoform type-2 , non-hepatic-type S-adenosylmethionine synthetase

GENE ID SPECIES
379867 Xenopus laevis
395032 Xenopus (Silurana) tropicalis
459363 Pan troglodytes
475770 Canis lupus familiaris
695362 Macaca mulatta
100339456 Oryctolagus cuniculus
100412649 Callithrix jacchus
4144 Homo sapiens
100173772 Pongo abelii
232087 Mus musculus
171347 Rattus norvegicus
100312974 Sus scrofa
527403 Bos taurus
323329 Danio rerio
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