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MECP2 Proteins

(Methyl CpG Binding Protein 2 (MECP2))
DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. In contrast to other MBD family members, MECP2 is X-linked and subject to X inactivation. MECP2 is dispensible in stem cells, but is essential for embryonic development. MECP2 gene mutations are the cause of most cases of Rett syndrome, a progressive neurologic developmental disorder and one of the most common causes of mental retardation in females. [provided by RefSeq, Jul 2009].
MECP2 Protein (AA 1-486) (GST tag) MECP2 Protein (AA 1-486) (GST tag) MECP2 Protein (AA 1-486) (GST tag) (ABIN1310622)

MECP2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA

MECP2 Protein (AA 329-486) (His tag) MECP2 Protein (AA 329-486) (His tag) MECP2 Protein (AA 329-486) (His tag) (ABIN7123936)

MECP2 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA

MECP2 Protein (AA 81-170) (GST tag) MECP2 Protein (AA 81-170) (GST tag) MECP2 Protein (AA 81-170) (GST tag) (ABIN1310624)

MECP2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA

MECP2 Proteins by Grade

Find MECP2 Proteins with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

MECP2 Proteins by Origin

Find MECP2 Proteins for a variety of species such as anti-Human MECP2, anti-Mouse MECP2, anti-Rat MECP2. The species listed below are among those available. Click on a link to go to the corresponding products.

MECP2 Proteins by Source

Here you will find MECP2 Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

MECP2 Proteins by Protein Type

Here you can find MECP2 Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

MECP2 Proteins by Application

Find MECP2 Proteins validated for a specific application such as ELISA, WB, SDS, AP. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular MECP2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
Cat. No. ABIN1310622
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7123936
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1310624
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3083495
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3120366
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7505031
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Human Cells
Validations
Cat. No. ABIN1945397
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Human Cells
Validations
Cat. No. ABIN7318777
Quantity 50 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7413304
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN2746868
Quantity 5 applications
Datasheet Datasheet
Reactivity Human
Source
Validations
Cat. No. ABIN1065539
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Cynomolgus
Source Yeast
Validations
Cat. No. ABIN1644051
Quantity 1 mg
Datasheet Datasheet
Reactivity Rat
Source Yeast
Validations
Cat. No. ABIN1473780
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our MECP2 Proteins

Nott, Cheng, Gao, Lin, Gjoneska, Ko, Minhas, Zamudio, Meng, Zhang, Jin, Tsai: "Histone deacetylase 3 associates with MeCP2 to regulate FOXO and social behavior." in: Nature neuroscience, Vol. 19, Issue 11, pp. 1497-1505, (2016) (PubMed).

Aliases for MECP2 Proteins

methyl-CpG binding protein 2 (MECP2) Proteins
methyl CpG binding protein 2 (Mecp2) Proteins
methyl CpG binding protein 2 (mecp2) Proteins
methyl-CpG binding protein 2 S homeolog (mecp2.S) Proteins
1500041B07Rik Proteins
AUTSX3 Proteins
BB130002 Proteins
D630021H01Rik Proteins
Mbd5 Proteins
MRX16 Proteins
MRX79 Proteins
MRXS13 Proteins
MRXSL Proteins
PPMX Proteins
RS Proteins
RTS Proteins
RTT Proteins
WBP10 Proteins
wu:fk96a04 Proteins
zgc:111857 Proteins
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