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anti-Methyl-CpG Binding Domain Protein 3 (MBD3) Antibodies

Does not bind DNA by itself. Additionally we are shipping MBD3 Proteins (6) and MBD3 Kits (1) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
MBD3 53615 O95983
MBD3 17192 Q9Z2D8
MBD3 362834  
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Top anti-MBD3 Antibodies at antibodies-online.com

Showing 10 out of 84 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-MBD3 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Transfected 293T 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB MBD3 Antibody (N-term) (ABIN657677) western blot analysis in 293 cell line lysates (35 µg/lane). This demonstrates the MBD3 antibody detected the MBD3 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from Jurkat cells, using MBD3 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of MBD3 (arrow) using rabbit polyclonal MBD3 Antibody (C-term) (ABIN387891).293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the MBD3 gene (Lane 2) (Origene Technologies). Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated WB MBD3 Antibody (C-term) (ABIN1882264) western blot analysis in K562 cell line lysates (35 µg/lane). This demonstrates the MBD3 antibody detected the MBD3 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-Mbd3 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: Mouse Heart WB Suggested Anti-Mbd3  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:1562500  Positive Control: Mouse Heart 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated IHC (p), WB 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL Log in to see 8 to 10 Days
$478.50
Details

MBD3 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , , ,
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Mouse (Murine)


Rat (Rattus)


Top referenced anti-MBD3 Antibodies

  1. Human Polyclonal MBD3 Primary Antibody for EIA, IHC (p) - ABIN356576 : Hendrich, Bird: Identification and characterization of a family of mammalian methyl-CpG binding proteins. in Molecular and cellular biology 1998 (PubMed)
    Show all 4 references for ABIN356576

  2. Human Monoclonal MBD3 Primary Antibody for WB - ABIN1882264 : Tatematsu, Yamazaki, Ishikawa: MBD2-MBD3 complex binds to hemi-methylated DNA and forms a complex containing DNMT1 at the replication foci in late S phase. in Genes to cells : devoted to molecular & cellular mechanisms 2000 (PubMed)
    Show all 4 references for ABIN1882264

  3. Chicken Polyclonal MBD3 Primary Antibody for WB - ABIN2778641 : Brown, Szyf: Epigenetic programming of the rRNA promoter by MBD3. in Molecular and cellular biology 2007 (PubMed)

  4. Human Polyclonal MBD3 Primary Antibody for IHC (p), WB - ABIN387891 : Bhattacharya, Ramchandani, Cervoni, Szyf: A mammalian protein with specific demethylase activity for mCpG DNA. in Nature 1999 (PubMed)

  5. Human Polyclonal MBD3 Primary Antibody for ELISA, WB - ABIN1533573 : Grimwood, Gordon, Olsen, Terry, Schmutz, Lamerdin, Hellsten, Goodstein, Couronne, Tran-Gyamfi, Aerts, Altherr, Ashworth, Bajorek, Black, Branscomb, Caenepeel, Carrano, Caoile, Chan, Christensen et al.: The DNA sequence and biology of human chromosome 19. ... in Nature 2004 (PubMed)

  6. Human Polyclonal MBD3 Primary Antibody for WB - ABIN657677 : Bachmann, Spengler, Binder, Eggermann: MBD3 mutations are not responsible for ICR1 hypomethylation in Silver-Russell syndrome. in European journal of medical genetics 2010 (PubMed)

More Antibodies against MBD3 Interaction Partners

Human Methyl-CpG Binding Domain Protein 3 (MBD3) interaction partners

  1. Insufficient MBD3 induced by small interfering RNA (siRNA) was found to result in a global DNA hypermethylation as well as increased methylation in the promoter CpG islands (CGIs) of a number of cell cycle related genes.

  2. This study investigates the genetic association between methyl-CpG-binding domain (MBD (show DPEP1 Antibodies)) gene polymorphisms and schizophrenia.

  3. These data suggest that MBD3, and by extension the NuRD complex, may have multiple roles in fine tuning expression for both active and silent genes, representing an important step in defining regulatory mechanisms

  4. reduced mRNA expression of MBD2 (show DPEP2 Antibodies) and MBD3 is implicated in gastric carcinogenesis.

  5. MBD3 is enriched at active promoters, whereas MBD2 (show DPEP2 Antibodies) is bound at methylated promoters and enriched at exon sequences of active genes.

  6. These factors lead to a binding affinity hierarchy of p66alpha (show GATAD2A Antibodies) for the different MBD2 (show DPEP2 Antibodies) homologues (MBD2 (show DPEP2 Antibodies) approximately MBD3 > MBD3L1 (show MBD3L1 Antibodies) approximately MBD3L2 (show MBD3L2 Antibodies)).

  7. MBD3 mutations are not responsible for ICR1 hypomethylation in Silver-Russell syndrome.

  8. MBD3 is highly expressed in glioblastome multiforme compared to astrocytoma and anaplastic astrocytoma

  9. interaction with two highly related p66 (show POLD3 Antibodies) proteins

  10. localization in Aurora-A (show AURKA Antibodies)-positive centrosomes in M phase

Mouse (Murine) Methyl-CpG Binding Domain Protein 3 (MBD3) interaction partners

  1. Cigarette smoke induces proteosomal-mediated degradation of Mbd-3 (show DEFB103A Antibodies) in embryonic orofacial cells.

  2. Although MBD3/NuRD is not required for neural stem cell lineage commitment, it is required to repress inappropriate transcription in progenitor cells and neurons to facilitate appropriate cell lineage choice and differentiation programmes.

  3. overexpression facilitates NANOG-mediated reprogramming in neural stem cells

  4. Data indicate an association of ovarian stimulation with a downregulation of mRNAs encoding the base excision repair proteins APEX1 (show APEX1 Antibodies) and POLB (show POLB Antibodies) as well as the 5-methyl-CpG-binding domain protein MBD3 in individual morula embryos.

  5. cyclin-dependent kinase 2-associated protein 1 (CDK2AP1 (show CDK2AP1 Antibodies)), an essential gene for early embryonic development, plays a role in pluripotency of ESC by engaging MBD3 to the promoter region of Wnt (show WNT2 Antibodies) signaling genes

  6. Study finds that Mbd3 and Brg1 (show SMARCA4 Antibodies) antagonistically regulate a common set of genes by regulating promoter nucleosome occupancy; furthermore, both Mbd3 and Brg1 (show SMARCA4 Antibodies) play key roles in the biology of 5-hydroxymethylcytosine.

  7. the transactivation domain of c-Jun (show JUN Antibodies) recruits Mbd3/NuRD to AP-1 (show JUN Antibodies) target genes to mediate gene repression, and this repression is relieved by JNK (show MAPK8 Antibodies)-mediated c-Jun (show JUN Antibodies) N-terminal phosphorylation

  8. Mbd3 helps restrict ES cells from differentiating towards the trophectoderm lineage and is an important epigenetic player in maintaining full pluripotency of mouse ES cells

  9. MBD3 protein is differentially expressed in principal neurons of the hippocampus and cortex, and in the adult retina.

  10. MBD3L2 (show MBD3L2 Antibodies) interacts with MBD3 and components of the NuRD complex and can oppose MBD2 (show MBD2 Antibodies)-MeCP1-mediated methylation silencing

MBD3 Antigen Profile

Protein Summary

Does not bind DNA by itself. Recruits histone deacetylases and DNA methyltransferases. Acts as transcriptional repressor and plays a role in gene silencing.

Gene names and symbols associated with MBD3

  • methyl-CpG binding domain protein 3 (mbd3) antibody
  • methyl-CpG binding domain protein 3 (MBD3) antibody
  • methyl-CpG binding domain protein 3 (Mbd3) antibody
  • AI181826 antibody
  • AU019209 antibody
  • DKFZp459N1635 antibody
  • MBD3 antibody
  • MGC69548 antibody
  • xmbd3 antibody

Protein level used designations for MBD3

methyl-CpG binding domain protein 3 , methyl-CpG binding protein MBD3 long form , methyl-CpG-binding domain protein 3 , methyl-CpG-binding protein MBD3

GENE ID SPECIES
398135 Xenopus laevis
448748 Xenopus (Silurana) tropicalis
455554 Pan troglodytes
100172033 Pongo abelii
53615 Homo sapiens
17192 Mus musculus
362834 Rattus norvegicus
770153 Gallus gallus
485080 Canis lupus familiaris
616090 Bos taurus
Selected quality suppliers for anti-MBD3 (MBD3) Antibodies
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