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MBD3L1 encodes a protein that is related to methyl-CpG-binding proteins but lacks the methyl-CpG binding domain. Additionally we are shipping MBD3L1 Antibodies (29) and MBD3L1 Proteins (5) and many more products for this protein.
These factors lead to a binding affinity hierarchy of p66alpha for the different MBD2 homologues (MBD2 approximately MBD3 > MBD3L1 approximately MBD3L2).
interacts with methyl-CpG-binding protein 2 (MBD2 (show MBD2 ELISA Kits)) and components of the NuRD complex
Mbd3l1 and Mbd3l2 are not involved in genome-wide demethylation of paternal genomes in mouse zygotes and are dispensable for normal development.
This gene encodes a protein that is related to methyl-CpG-binding proteins but lacks the methyl-CpG binding domain. The protein is localized to discrete areas in the nucleus, and expression appears to be restricted to round spermatids, suggesting that the protein plays a role in the postmeiotic stages of male germ cell development.
MBD3-like protein 1
, methyl-CpG-binding domain protein 3-like 1