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anti-Methyl-CpG Binding Domain Protein 5 (MBD5) Antibodies

MBD5 encodes a member of the methyl-CpG-binding domain (MBD) family. Additionally we are shipping Methyl-CpG Binding Domain Protein 5 Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
MBD5 55777 Q9P267
MBD5 109241  
MBD5 311026  
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Top anti-Methyl-CpG Binding Domain Protein 5 Antibodies at antibodies-online.com

Showing 10 out of 18 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated ELISA, WB   100 μg Log in to see 8 to 10 Days
$449.17
Details
Human Mouse Un-conjugated IF, ELISA, WB Western Blot analysis of MBD5 expression in transfected 293T cell line by MBD5 monoclonal antibody (M01), clone 4A12-1B6.Lane 1: MBD5 transfected lysate(24.3 KDa).Lane 2: Non-transfected lysate. Detection limit for recombinant GST tagged MBD5 is 0.03 ng/ml as a capture antibody. 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated WB   50 μL Log in to see 8 to 10 Days
$463.83
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (51.3 KDa) . 50 μL Log in to see 9 Days
$298.57
Details
Human Rabbit Un-conjugated ELISA, WB   50 μL Log in to see 9 to 11 Days
$313.50
Details
Human Rabbit Un-conjugated WB MBD5 MaxPab rabbit polyclonal antibody. Western Blot analysis of MBD5 expression in human liver. Western Blot analysis of MBD5 expression in transfected 293T cell line by MBD5 MaxPab polyclonal antibody.Lane 1: MBD5 transfected lysate(24.30 KDa).Lane 2: Non-transfected lysate. 100 μg Log in to see 9 Days
$418.57
Details
Human Mouse Un-conjugated ELISA, WB   100 μg Log in to see 8 to 10 Days
$742.50
Details
Human Rabbit Un-conjugated WB   100 μL Log in to see 2 to 3 Days
$240.90
Details
Human Mouse Un-conjugated ELISA, WB   100 μg Log in to see 11 to 16 Days
$553.14
Details
Human Rabbit Un-conjugated ELISA, WB   50 μL Log in to see 3 to 4 Days
$510.36
Details

MBD5 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human ,
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Mouse (Murine) ,


Rat (Rattus)


More Antibodies against Methyl-CpG Binding Domain Protein 5 Interaction Partners

Human Methyl-CpG Binding Domain Protein 5 (MBD5) interaction partners

  1. Circadian rhythm gene expression altered by haploinsufficiency of MBD5.

  2. Results show that when MBD5 and RAI1 (show DOM3Z Antibodies) are haploinsufficient, they perturb several common pathways that are linked to neuronal and behavioral development.

  3. Reduced MBD5 dosage leads to mRNA and microRNA expression patterns and DNA methylation (show HELLS Antibodies) patterns more characteristic of differentiating than proliferating neural stem cells. This balance change may underlie neurodevelopmental disorders.

  4. We studied and showed that both MBD5 and MBD6 (show MBD6 Antibodies) interact with the mammalian PR-DUB Polycomb (show CBX2 Antibodies) protein complex in a mutually exclusive manner, and that the MBD (show DPEP1 Antibodies) of MBD5 and MBD6 (show MBD6 Antibodies) is both necessary and sufficient to mediate this interaction.

  5. The features associated with a deletion, mutation or duplication of MBD5 and the gene expression changes observed support MBD5 as a dosage-sensitive gene critical for normal development.

  6. study demonstrates that haploinsufficiency of MBD5 causes diverse phenotypes, yields insight into the spectrum of resulting neurodevelopmental and behavioral psychopathology and provides clinical context for interpretation of MBD5 structural variations.

  7. A genomic copy number variant analysis implicates the MBD5 and HNRNPU (show HNRNPU Antibodies) genes in Chinese children with infantile spasms and expands the clinical spectrum of 2q23.1 deletion.

  8. Identified de novo intragenic deletions of MBD5 in three patients.

  9. MBD5 was tied to neurodevelopmental disorders following the identification of microdeletions on chromosome 2q22-2q23.

  10. MBD5 is a single causal locus as shown by 2q23.1 microdeletion syndrome with roles in intellectual disability, epilepsy, and autism spectrum disorder

Mouse (Murine) Methyl-CpG Binding Domain Protein 5 (MBD5) interaction partners

  1. This study indicates that the Mbd5(+/) (GT) mouse model recapitulates most of the hallmark phenotypes observed in 2q23.1 deletion carriers including abnormal social behavior, cognitive impairment, and motor and craniofacial abnormalities.

  2. MBD5 regulates iron metabolism via methylation-independent genomic targeting of Fth1 (show FTH1 Antibodies).

  3. These results indicate Mbd5 as an essential factor for mouse postnatal growth and maintenance of glucose homeostasis

Methyl-CpG Binding Domain Protein 5 (MBD5) Antigen Profile

Protein Summary

This gene encodes a member of the methyl-CpG-binding domain (MBD) family. The MBD consists of about 70 residues and is the minimal region required for a methyl-CpG-binding protein binding specifically to methylated DNA. In addition to the MBD domain, this protein contains a PWWP domain (Pro-Trp-Trp-Pro motif), which consists of 100-150 amino acids and is found in numerous proteins that are involved in cell division, growth and differentiation. Mutations in this gene cause mental retardation autosomal dominant type 1. Haploinsufficiency of this gene is associated with a syndrome involving microcephaly, intellectual disabilities, severe speech impairment, and seizures. Alternatively spliced transcript variants have been found, but their full-length nature is not determined.

Gene names and symbols associated with MBD5

  • methyl-CpG binding domain protein 5 (MBD5) antibody
  • methyl-CpG binding domain protein 5 (mbd5) antibody
  • methyl-CpG binding domain protein 5 (Mbd5) antibody
  • 9430004D19Rik antibody
  • AA536666 antibody
  • AI426407 antibody
  • C030040A15Rik antibody
  • MBD5 antibody
  • MRD1 antibody
  • OTTMUSG00000012483 antibody

Protein level used designations for MBD5

methyl-CpG binding domain protein 5 , methyl-CpG-binding domain protein 5 , methyl-CpG-binding domain protein 5-like , methyl-CpG-binding protein MBD5

GENE ID SPECIES
424308 Gallus gallus
483910 Canis lupus familiaris
541084 Bos taurus
721892 Macaca mulatta
100049894 Equus caballus
100145640 Xenopus (Silurana) tropicalis
100397398 Callithrix jacchus
100483698 Ailuropoda melanoleuca
100561778 Anolis carolinensis
55777 Homo sapiens
109241 Mus musculus
311026 Rattus norvegicus
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