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Methylcrotonoyl-CoA Carboxylase 1 (Alpha) Proteins (MCCC1)

MCCC1 encodes the large subunit of 3-methylcrotonyl-CoA carboxylase. Additionally we are shipping Methylcrotonoyl-CoA Carboxylase 1 (Alpha) Antibodies (31) and Methylcrotonoyl-CoA Carboxylase 1 (Alpha) Kits (1) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
MCCC1 56922 Q96RQ3
MCCC1 294972 Q5I0C3
MCCC1 72039 Q99MR8
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Top Methylcrotonoyl-CoA Carboxylase 1 (Alpha) Proteins at antibodies-online.com

Showing 4 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,967.33
Details

MCCC1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Rat (Rattus)

Mouse (Murine)

More Proteins for Methylcrotonoyl-CoA Carboxylase 1 (Alpha) (MCCC1) Interaction Partners

Human Methylcrotonoyl-CoA Carboxylase 1 (Alpha) (MCCC1) interaction partners

  1. Novel mutations in MCCC1 gene were identified in Chinese population. The expression profiles of two splice mutations (c.639+2T>A and c.639+5G>T) were also characterized.

  2. Four new point mutations were detected in the MCCC1 gene in patients with maternal 3-methylcrotonyl coenzyme deficiency.

  3. This study demonistrated that Mainland China demonstrates that MCCC1/LAMP3 (show CD63 Proteins) (rs11711441) is associated with a lower risk of Parkinson's disease.

  4. 3-methylcrotonyl-CoA carboxylase (show MCCC2 Proteins) inhibition has a role in increased excretion of 3-hydroxyisovaleric acid in valproate-treated patients

  5. Mutation in 3-methylcrotonyl CoA carboxylase 1 gene is associated with 3-methylcrotonyl-CoA carboxylase (show MCCC2 Proteins) deficiency.

  6. study reports eight different mutant alleles of MCCC1 or MCCC2 (show MCCC2 Proteins) including six novel mutations in Korean patients with 3-methylcrotonyl-CoA carboxylase (show MCCC2 Proteins) (MCC (show MCC Proteins)) deficiency

  7. identified two novel MCCA and four novel MCCB mutant alleles from five MCC (show MCC Proteins)-deficient patients

  8. factors other than the genotype at the MCCA and MCCB loci have a major influence on the phenotype of MCC (show MCC Proteins) deficiency

  9. The amino-termini containing 39 (MCCalpha) or 20 amino acids (MCCbeta) were both necessary and sufficient for targeting. Structural requirements for mitochondrial import were defined by site-directed mutagenesis.

  10. Molecular analyses revealed novel mutations in one of the causative genes, MCCA or MCCB, in all five of the MCC (show MCC Proteins) deficiency patients

Arabidopsis thaliana Methylcrotonoyl-CoA Carboxylase 1 (Alpha) (MCCC1) interaction partners

  1. Studies indicate that mutations in either 3-methylcrotonyl CoA carboxylase (show MCCC2 Proteins) MCCA (At1g03090) or MCCB (show MCCC2 Proteins) (At4g34030) block mitochondrial Leu catabolism, as inferred from the increased accumulation of Leu.

Methylcrotonoyl-CoA Carboxylase 1 (Alpha) (MCCC1) Protein Profile

Protein Summary

This gene encodes the large subunit of 3-methylcrotonyl-CoA carboxylase. This enzyme functions as a heterodimer and catalyzes the carboxylation of 3-methylcrotonyl-CoA to form 3-methylglutaconyl-CoA. Mutations in this gene are associated with 3-Methylcrotonylglycinuria, an autosomal recessive disorder of leucine catabolism.

Gene names and symbols associated with MCCC1

  • methylcrotonoyl-CoA carboxylase 1 (alpha) (MCCC1)
  • methylcrotonoyl-CoA carboxylase 1 (alpha) (Mccc1)
  • methylcrotonoyl-CoA carboxylase subunit alpha (MCCA)
  • methylcrotonoyl-Coenzyme A carboxylase 1 (alpha) (Mccc1)
  • 1810045E08Rik protein
  • 2310058B18Rik protein
  • MCC-B protein
  • Mcca protein
  • MCCalpha protein
  • R75106 protein

Protein level used designations for MCCC1

3-methylcrotonyl-CoA carboxylase 1 , 3-methylcrotonyl-CoA carboxylase biotin-containing subunit , 3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha , MCCase subunit alpha , methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial , methylcrotonoyl-Coenzyme A carboxylase 1 (alpha)

GENE ID SPECIES
56922 Homo sapiens
294972 Rattus norvegicus
838362 Arabidopsis thaliana
72039 Mus musculus
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