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anti-Methylenetetrahydrofolate Reductase (NAD(P)H) (MTHFR) Antibodies

The protein encoded by MTHFR catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine. Additionally we are shipping MTHFR Kits (16) and MTHFR Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
MTHFR 17769 Q9WU20
MTHFR 4524 P42898
MTHFR 362657  
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Top anti-MTHFR Antibodies at

Showing 10 out of 103 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB MTHFR Antibody (Center) (ABIN1881559) western blot analysis in CEM cell line lysates (35 µg/lane). This demonstrates the MTHFR antibody detected the MTHFR protein (arrow). 400 μL Log in to see 10 to 11 Days
Human Mouse Un-conjugated IHC, ELISA, WB Figure 1: Red: Control Antigen (100 ng), Purple: Antigen (10ng), Green: Antigen (50 ng), Blue: Antigen (100 ng) Figure 2: Immunohistochemical analysis of paraffin-embedded lung cancer using MTHFR mouse mAb with DAB staining. 100 μL Log in to see 3 to 4 Days
Mouse Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
Human Rabbit Un-conjugated WB WB Image Sample (30 ug of whole cell lysate) A: A549 7.5% SDS PAGE antibody diluted at 1:1000 WB Image Various tissue extracts (50 μg) were separated by 7.5% SDS-PAGE, and the membrane was blotted with MTHFR antibody [N3C3] , diluted at 1:1000. 100 μL Log in to see 2 to 3 Days
Human Mouse Un-conjugated IF, ELISA, WB Immunofluorescence of monoclonal antibody to MTHFR on HeLa cell. [antibody concentration 10 ug/ml] Detection limit for recombinant GST tagged MTHFR is 1 ng/ml as a capture antibody. 100 μg Log in to see 9 Days
Human Mouse Un-conjugated IHC, ELISA, WB 100 μL Log in to see 8 to 10 Days
Cow Goat Un-conjugated EIA, WB AP31698PU-N (0.3µg/ml) staining of NIH3T3 lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 6 to 8 Days
Human Goat Un-conjugated IHC (p), ELISA Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 8 to 10 Days
Human Rabbit Un-conjugated WB Western blot analysis of MTHFR expression in HEK293 (A), Jurkat (B), A549 (C) whole cell lysates. 200 μL Log in to see 9 Days
Human Rabbit Un-conjugated WB 100 μL Log in to see 8 to 10 Days

MTHFR Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-MTHFR Antibodies

  1. Human Polyclonal MTHFR Primary Antibody for WB - ABIN1881559 : Singh, Singh, Raman: MTHFR A1298C polymorphism and idiopathic male infertility. in Journal of postgraduate medicine 2010 (PubMed)
    Show all 5 references for ABIN1881559

  2. Human Monoclonal MTHFR Primary Antibody for IF, ELISA - ABIN561866 : Forges, Chery, Audonnet, Feillet, Gueant: Life-threatening methylenetetrahydrofolate reductase (MTHFR) deficiency with extremely early onset: characterization of two novel mutations in compound heterozygous patients. in Molecular genetics and metabolism 2010 (PubMed)
    Show all 3 references for ABIN561866

  3. Human Monoclonal MTHFR Primary Antibody for IHC, ELISA - ABIN969297 : Sarecka-Hujar, Zak, Krauze: Carrier-state of two or three polymorphic variants of MTHFR, IL-6 and ICAM1 genes increases the risk of coronary artery disease. in Kardiologia polska 2009 (PubMed)
    Show all 2 references for ABIN969297

More Antibodies against MTHFR Interaction Partners

Mouse (Murine) Methylenetetrahydrofolate Reductase (NAD(P)H) (MTHFR) interaction partners

  1. Study demonstrated that maternal MTHFR deficiency (i.e., in utero MTHFR deficiency) and early life exposure to vigabatrin separately and together alter the levels of proteins in the glutamatergic synapse

  2. Mildly hyperhomocysteinemic Mthfr+/- mice demonstrate reduced ganglion cell function, thinner NFL (show NEFL Antibodies), and mild vasculopathy by 24 weeks.

  3. DNA methylation (show HELLS Antibodies) patterns in undifferentiated spermatogonia are relatively stable in culture over time under conditions of altered methionine and MTHFR levels.

  4. Data from Mthfr knockout mice (in homozygous/heterozygous matings) suggest that maternal genotype contributes to sensitivity to arsenic as embryotoxin (i.e., genetic predisposition to fetal resorption/congenital malformation in arsenic poisoning).

  5. our results support an interaction between mild neonatal stress, the MTHFR genotype and sex

  6. investigation of Mthfr regulation in an in vivo mouse model revealed temporal- and tissue-specific regulation that supports important roles for MTHFR in the developing embryo, and in postnatal brain and male reproductive tissues

  7. A possible mechanism for the epigenetic involvement of Mthfr deficiency is proposed in the gender-dependent regulation of proteins associated with plasticity of the excitatory synapse.

  8. These results showed that methylenetetrahydrofolate reductase deficiency impairs endothelial progenitor cell formation and increases endothelial progenitor cell senescence by endothelial nitric oxide synthase (show NOS3 Antibodies) uncoupling and downregulation of SIRT1 (show SIRT1 Antibodies).

  9. Variable presentation of MTHFR deficiency in different genetic backgrounds; plasma homocysteine is not a predictor of severity.

  10. Newborn reflex development was slightly influenced by Mthfr +/- genotype and by the combination genotype and the neonatal vigabatrin (GVG) administration, in a sex-independent manner. Females presented attenuated anxiety due to Mthfr +/- genotype and GVG.

Human Methylenetetrahydrofolate Reductase (NAD(P)H) (MTHFR) interaction partners

  1. The prognostic index comprising XRCC1 (show XRCC1 Antibodies) rs25487, ERCC2 (show ERCC2 Antibodies) rs13181, and rs1799793 polymorphisms may be a useful predictor of clinical outcomes in MGC treated with EOF.

  2. The prevalence of factor V G1691A, prothrombin (show F2 Antibodies) G20210A and MTHFR C677T single nucleotide polymorphism among Syrians is 11.5%, 2.5% and 84.5%, respectively.

  3. MTHFR C677T polymorphism, qualitatively, is not a genetic factor for the pathogenesis of psoriasis but could quantitatively reflect the severity of psoriasis to some extent. Meta-analysis.

  4. the studied polymorphisms MTHFR C677T (rs1801133) and MTR (show MTR Antibodies) A2756G (rs1805087) do not contribute to genetic susceptibility to varicose veins in ethnical Russians.

  5. the influence of polymorphisms in methylenetetrahydrofolate reductase (MTHFR-C677T) and apolipoprotein-E (apo-E (show APOE Antibodies)) as risk factors for ischemic stroke patients in south Indian population

  6. Rheumatoid arthritis patients with the MTHFR 677TT genotype had the highest asymmetric dimethylarginine levels, significantly higher than either those patients carrying the MTHFR 677CT or the MTHFR 677CC genotype.

  7. There is an association between variants of the MTHFR gene and hypertension in Cameroonian patients from the South West region.

  8. There were no other associations between single -nucleotide polymorphisms and the efficacy of MTX (show MTX1 Antibodies) treatment. CONCLUSIONS: The MTHFR 677CC and GGH (show GGH Antibodies) 401TT and CT genotypes were associated with a reduction in the number of MTX (show MTX1 Antibodies)-related adverse events.

  9. Frequency of MTHFR risk allele (T) in patients with maternal age <25 years is marginally significant higher than those in cases with maternal age >/=25 years (p = .069) with an OR of 2.7 (95% CI = 0.90-8.07). Conclusions: MTHFR is a common susceptibility factor for gastroschisis in Indonesia.

  10. The association of colorectal adenomas with the rs6983267 variant at 8q24 was considered as 'highly credible', the 'less credible' associations were identified with a further four variants of four independent genes: MTHFR c.677C>T p.A222V(rs1801133), TP53 (show TP53 Antibodies) c.215C>G p.R72P (rs1042522), NQO1 (show NQO1 Antibodies) c.559C>T p.P187S (rs1800566), and NAT1 (show EIF4G2 Antibodies) alleles imputed as fast acetylator genotypes. [meta-analysis]

MTHFR Antigen Profile

Protein Summary

The protein encoded by this gene catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine. Genetic variation in this gene influences susceptibility to occlusive vascular disease, neural tube defects, colon cancer and acute leukemia, and mutations in this gene are associated with methylenetetrahydrofolate reductase deficiency.

Gene names and symbols associated with MTHFR

  • methylenetetrahydrofolate reductase (NAD(P)H) (mthfr) antibody
  • methylenetetrahydrofolate reductase (NAD(P)H) (MTHFR) antibody
  • methylenetetrahydrofolate reductase (metF) antibody
  • methylenetetrahydrofolate reductase (DDB_G0279137) antibody
  • 5,10-methylenetetrahydrofolate reductase (Mthfr) antibody
  • methylenetetrahydrofolate reductase (NAD(P)H) (Mthfr) antibody
  • AI323986 antibody
  • DDBDRAFT_0204686 antibody
  • DDBDRAFT_0230137 antibody
  • DDB_0204686 antibody
  • DDB_0230137 antibody

Protein level used designations for MTHFR

5,10-methylenetetrahydrofolate reductase , 5,10-methylenetetrahydrofolate reductase (NADPH) , methylenetetrahydrofolate reductase (NAD(P)H) , methylenetetrahydrofolate reductase-like , methylenetetrahydrofolate reductase

379784 Xenopus laevis
469800 Pan troglodytes
100125082 Xenopus (Silurana) tropicalis
100391000 Callithrix jacchus
1209960 Coxiella burnetii RSA 493
8621890 Dictyostelium discoideum AX4
17769 Mus musculus
4524 Homo sapiens
362657 Rattus norvegicus
478230 Canis lupus familiaris
397180 Sus scrofa
497032 Bos taurus
419489 Gallus gallus
100715703 Cavia porcellus
Selected quality suppliers for anti-MTHFR (MTHFR) Antibodies
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