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anti-Methylthioadenosine phosphorylase (MTAP) Antibodies

MTAP encodes an enzyme that plays a major role in polyamine metabolism and is important for the salvage of both adenine and methionine. Additionally we are shipping MTAP Proteins (15) and MTAP Kits (9) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
MTAP 4507 Q13126
MTAP 66902 Q9CQ65
MTAP 298227  
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Top anti-MTAP Antibodies at antibodies-online.com

Showing 10 out of 51 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB MTAP Antibody (N-term) (ABIN1881557) western blot analysis in MDA-MB453 cell line lysates (35 µg/lane). This demonstrates the MTAP antibody detected the MTAP protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated ICC, IF, IP, IHC (p), WB WB Image MTAP antibody detects MTAP protein by western blot analysis. Various whole cell extracts (30 μg) were separated by 12% SDS-PAGE, and the membrane was blotted with MTAP antibody , diluted at a dilution of 1:2000. IHC-P Image Immunohistochemical analysis of paraffin-embedded SAS xenograft , using MTAP, antibody at 1:500 dilution. 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Mouse Un-conjugated IF, ELISA, WB Immunofluorescence of monoclonal antibody to MTAP on HeLa cell. [antibody concentration 10 ug/ml] MTAP monoclonal antibody (M01), clone 2G4 Western Blot analysis of MTAP expression in HeLa . 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated IHC, WB 100 μL Log in to see 14 Days
$369.79
Details
Human Mouse Un-conjugated IF, WB Immunofluorescence of monoclonal antibody to MTAP on HeLa cell (antibody concentration 10 µg/mL). MTAP monoclonal antibody (M01), clone 2G4 Western Blot analysis of MTAP expression in HeLa. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated IHC (p), WB   100 μL Log in to see 8 to 10 Days
$507.83
Details
Human Rabbit Un-conjugated WB 400 μL Log in to see 6 Days
$457.14
Details
Human Rabbit Un-conjugated IHC (fp), WB 100 μL Log in to see 6 to 11 Days
$485.71
Details
Human Rabbit Un-conjugated IF   50 μL Log in to see 8 to 10 Days
$390.50
Details
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged MTAP is 0.3 ng/ml as a capture antibody. Western Blot detection against Immunogen (56.87 KDa) . 100 μg Log in to see 9 Days
$430.00
Details

MTAP Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , ,
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Mouse (Murine)


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Rat (Rattus)


Top referenced anti-MTAP Antibodies

  1. Human Polyclonal MTAP Primary Antibody for WB - ABIN1881557 : Newton-Bishop, Chang, Iles, Taylor, Bakker, Chan, Leake, Karpavicius, Haynes, Fitzgibbon, Elliott, Kanetsky, Harland, Barrett, Bishop: Melanocytic nevi, nevus genes, and melanoma risk in a large case-control study in the United Kingdom. in Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2010 (PubMed)
    Show all 3 references for ABIN1881557

  2. Human Monoclonal MTAP Primary Antibody for IF, ELISA - ABIN561859 : Rose, Poliseno, Wang, Clark, Pearlman, Wang, Vega Y Saenz de Miera, Medicherla, Christos, Shapiro, Pavlick, Darvishian, Zavadil, Polsky, Hernando, Ostrer, Osman: Integrative genomics identifies molecular alterations that challenge the linear model of melanoma progression. in Cancer research 2011 (PubMed)

More Antibodies against MTAP Interaction Partners

Human Methylthioadenosine phosphorylase (MTAP) interaction partners

  1. MTAP expression was significantly higher in Luminal-A breast tumors than in triple negative breast neoplasms, suggesting the lack of expression in more aggressive breast tumors.

  2. study to describe MTAP expression in a series of Pilocytic astrocytomas and relate it to the clinicopathological features of the patients; found MTAP expression is retained in Pilocytic astrocytomas and is not an outcome predictor for these tumors

  3. MTAP deficiency was predictive of worse disease-specific survival and distant metastasis-free survival, suggesting its role in disease progression and as an independent prognostic biomarker of nasopharyngeal carcinoma

  4. In the MTAP-deficient cases, the homozygous deletion of MTAP predicted adverse outcome. In MTAP-deficient cells, MTAP reexpression inhibited cell migration and invasion, proliferation and anchorage-independent colony formation and downregulated cyclin D1 (show CCND1 Antibodies).

  5. MTAP expression is an independent prognostic factor and has greater prognostic significance than p16 (show CDKN2A Antibodies) expression in non-small cell lung cancer and concordant loss of MTAP and p16 (show CDKN2A Antibodies) expression indicates poor outcomes in lung cancer patients.

  6. MTAP-mediated regulation of methylthioadenosine links polyamine metabolism with NF-kappaB (show NFKB1 Antibodies) activation and apoptosis in hepatic stellate cells.

  7. SNP rs10118757 was associated with CAD (show CAD Antibodies) risk in a Chinese Han population, indicating that MTAP gene may play a potential role in the pathophysiological process of CAD (show CAD Antibodies).

  8. Homozygous deletion of MTAP gene is associated with haploid lymphoblastic leukemia.

  9. Authors report here that a high percentage of t-cell lymphoma lack the enzyme methylthioadenosine phosphorylase (MTAP).

  10. MTAP gene might be involved in the etiology of myocardial infarction in Chinese Han ethnicity.

Mouse (Murine) Methylthioadenosine phosphorylase (MTAP) interaction partners

  1. MTAP-mediated regulation of methylthioadenosine links polyamine metabolism with NF-kappaB (show NFKB1 Antibodies) activation and apoptosis in hepatic stellate cells.

  2. Regulation of MTAP by reactive oxygen species might participate in the redox regulation of the methionine catabolic pathway in the liver

  3. Studies show that Mtap is a tumor suppressor gene independent of CDKN2A (show CDKN2A Antibodies) and ARF (show CDKN2A Antibodies).

MTAP Antigen Profile

Protein Summary

This gene encodes an enzyme that plays a major role in polyamine metabolism and is important for the salvage of both adenine and methionine. The encoded enzyme is deficient in many cancers because this gene and the tumor suppressor p16 gene are co-deleted. Multiple alternatively spliced transcript variants have been described for this gene, but their full-length natures remain unknown.

Gene names and symbols associated with MTAP

  • methylthioadenosine phosphorylase (mtaP) antibody
  • methylthioadenosine phosphorylase (Mmah_0779) antibody
  • methylthioadenosine phosphorylase (Mmah_0844) antibody
  • methylthioadenosine phosphorylase (Tagg_1015) antibody
  • methylthioadenosine phosphorylase (Slip_0897) antibody
  • methylthioadenosine phosphorylase (Slip_1284) antibody
  • methylthioadenosine phosphorylase (Toce_0364) antibody
  • methylthioadenosine phosphorylase (Vdis_0648) antibody
  • methylthioadenosine phosphorylase (Mfer_0491) antibody
  • methylthioadenosine phosphorylase (Intca_0886) antibody
  • methylthioadenosine phosphorylase (Desmu_1057) antibody
  • methylthioadenosine phosphorylase (Dester_1490) antibody
  • methylthioadenosine phosphorylase (Arcve_1093) antibody
  • methylthioadenosine phosphorylase (Mahau_1873) antibody
  • methylthioadenosine phosphorylase (Mzhil_0273) antibody
  • methylthioadenosine phosphorylase (MTAP) antibody
  • methylthioadenosine phosphorylase (Mtap) antibody
  • methylthioadenosine phosphorylase (mtap) antibody
  • 1300019I21Rik antibody
  • BDMF antibody
  • c86fus antibody
  • Cc1-6 antibody
  • DMSFH antibody
  • DMSMFH antibody
  • LGMBF antibody
  • MSAP antibody
  • MTAPase antibody
  • zgc:66012 antibody

Protein level used designations for MTAP

methylthioadenosine phosphorylase , 5'-methylthioadenosine phosphorylase , MTA phosphorylase , MTAPase , MeSAdo phosphorylase , S-methyl-5'-thioadenosine phosphorylase , CG4802-like

GENE ID SPECIES
3230190 Dehalococcoides ethenogenes 195
8982941 Methanohalophilus mahii DSM 5219
8983006 Methanohalophilus mahii DSM 5219
9166038 Thermosphaera aggregans DSM 11486
9273683 Syntrophothermus lipocalidus DSM 12680
9274073 Syntrophothermus lipocalidus DSM 12680
9509999 Thermosediminibacter oceani DSM 16646
9751569 Vulcanisaeta distributa DSM 14429
9962213 Methanothermus fervidus DSM 2088
10083682 Intrasporangium calvum DSM 43043
10153764 Desulfurococcus mucosus DSM 2162
10270747 Desulfurobacterium thermolithotrophum DSM 11699
10394208 Archaeoglobus veneficus SNP6
10608635 Mahella australiensis 50-1 BON
10821877 Methanosalsum zhilinae DSM 4017
4507 Homo sapiens
66902 Mus musculus
298227 Rattus norvegicus
709020 Macaca mulatta
782907 Bos taurus
393526 Danio rerio
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