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METTL3 encodes the 70 kDa subunit of MT-A which is part of N6-adenosine-methyltransferase. Additionally we are shipping METTL3 Proteins (4) and METTL3 Kits (2) and many more products for this protein.
Showing 10 out of 24 products:
Bat Polyclonal METTL3 Primary Antibody for WB - ABIN610637
Ginkel, Wordeman: Expression and partial characterization of kinesin-related proteins in differentiating and adult skeletal muscle. in Molecular biology of the cell 2000
Show all 2 references for 610637
Cow (Bovine) Polyclonal METTL3 Primary Antibody for WB - ABIN2781087
Beausoleil, Villén, Gerber, Rush, Gygi: A probability-based approach for high-throughput protein phosphorylation analysis and site localization. in Nature biotechnology 2006
Cow (Bovine) Polyclonal METTL3 Primary Antibody for WB - ABIN2775893
Bujnicki, Feder, Radlinska, Blumenthal: Structure prediction and phylogenetic analysis of a functionally diverse family of proteins homologous to the MT-A70 subunit of the human mRNA:m(6)A methyltransferase. in Journal of molecular evolution 2002
For the methylation of adenosine in RNA, Mettl3 is the catalytically active subunit, while Mettl14 (show METTL14 Antibodies) plays a structural role critical for substrate recognition.
METTL3 enhances mRNA translation through an interaction with the translation initiation machinery in lung adenocarcinoma cells.
miR (show MLXIP Antibodies)-33a can attenuatenon-small-cell lung carcinoma cells proliferation via targeting to the 3'-untranslated region of METTL3 mRNA.
Structure of the METTL3-METTL14 (show METTL14 Antibodies) complex
Study identifies m(6)A methylation sites on many clock gene transcripts and shows that specific inhibition of m(6)A methylation by silencing of the m(6)A methylase Mettl3 is sufficient to elicit circadian period elongation and RNA processing delay.
this study identifies Mettl3, an N(6)-methyladenosine (m(6)A) transferase, as a regulator for terminating murine naive pluripotency.
This gene encodes the 70 kDa subunit of MT-A which is part of N6-adenosine-methyltransferase. This enzyme is involved in the posttranscriptional methylation of internal adenosine residues in eukaryotic mRNAs, forming N6-methyladenosine.
N6-adenosine-methyltransferase 70 kDa subunit
, adoMet-binding subunit of the human mRNA (N6-adenosine)-methyltransferase
, mRNA m(6)A methyltransferase
, methyltransferase-like protein 3
, m6a methyltransferase
, methyltransferase-like 3