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Mevalonate Kinase Proteins (MVK)

MVK encodes the peroxisomal enzyme mevalonate kinase. Additionally we are shipping Mevalonate Kinase Antibodies (85) and Mevalonate Kinase Kits (1) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
MVK 4598 Q03426
MVK 17855 Q9R008
MVK 81727 P17256
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Top Mevalonate Kinase Proteins at antibodies-online.com

Showing 10 out of 16 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Baculovirus infected Insect Cells Human His tag,GST tag 50 μg Log in to see 16 Days
$272.80
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 7 to 8 Days
$319.00
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Archaeoglobus fulgidus His tag   1 mg Log in to see 56 to 66 Days
$2,746.33
Details
Yeast Thermococcus sibiricus His tag   1 mg Log in to see 56 to 66 Days
$2,898.50
Details
Yeast Pyrococcus His tag   1 mg Log in to see 56 to 66 Days
$2,902.17
Details
Yeast Thermococcus onnurineus His tag   1 mg Log in to see 56 to 66 Days
$2,902.17
Details
Yeast Thermococcus gammatolerans His tag   1 mg Log in to see 56 to 66 Days
$2,902.17
Details

MVK Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, ,
Mouse (Murine)

Rat (Rattus)

Top referenced Mevalonate Kinase Proteins

  1. Human MVK Protein expressed in Escherichia coli (E. coli) - ABIN1098525 : Cuisset, Drenth, Simon, Vincent, van der Velde Visser, van der Meer, Grateau, Delpech: Molecular analysis of MVK mutations and enzymatic activity in hyper-IgD and periodic fever syndrome. in European journal of human genetics : EJHG 2001 (PubMed)
    Show all 2 references for ABIN1098525

  2. Human MVK Protein expressed in Baculovirus infected Insect Cells - ABIN2005998 : Schafer, Bishop, Kratunis, Kalinowski, Mosley, Gibson, Tanaka: Molecular cloning of human mevalonate kinase and identification of a missense mutation in the genetic disease mevalonic aciduria. in The Journal of biological chemistry 1992 (PubMed)

More Proteins for Mevalonate Kinase (MVK) Interaction Partners

Human Mevalonate Kinase (MVK) interaction partners

  1. this study extends the mutation spectrum of MVK; MVK protein stability and correct folding might be the molecular mechanism causing disseminated superficial actinic porokeratosis

  2. predictive analysis of mutations in MVK to predict disease severity

  3. study reports a novel mutation of the MVK gene in Chinese patients with disseminated superficial actinic porokeratosis (DSAP); result confirms the involvement of MVK gene in DSAP

  4. results from this 4 generation family imply a causal relationship between MVK and perokeratosis.

  5. Results suggest that the effects of MVK mutations in Behcet's disease could be an additional genetic susceptibility factor for the patients with neurological involvement.

  6. The testing for the Hyper IgD Syndrome was positive for the pV377I/c.1129 G>A heterozygosity in a patient with periodic fever.

  7. Report a novel missense mutation in mevalonate kinase responsible for disseminated superficial actinic porokeratosis.

  8. study reportstwo novel mutations of the MVK gene in Chinese patients with disseminated superficial actinic porokeratosis

  9. These results suggest that hCG (show CGA Proteins)-induced down-regulation of LHR (show LHCGR Proteins) mRNA expression is mediated by activation of cAMP/PKA/ERK (show EPHB2 Proteins) pathways to increase miR (show MLXIP Proteins)-122 expression, which then increases LRBP expression through the activation of SREBPs.

  10. In the current article, we add another phenotype to the spectrum of diverging disorders associated with mutations in MVK.

Mouse (Murine) Mevalonate Kinase (MVK) interaction partners

  1. analyis of the aberrant expression of costimulatory molecules in splenocytes of the mevalonate kinase-deficient mouse model of human hyper-IgD syndrome

  2. PTH (show PTH Proteins) stimulated BMP-2 (show BMP2 Proteins) mRNA expression via the mevalonate pathway and ROK (show GRK1 Proteins) in osteoblastic MC3T3-E1 cells

  3. a mevalonate kinase (Mvk) allele deletion yields a murine model of hyper-IgD syndrome

Cow (Bovine) Mevalonate Kinase (MVK) interaction partners

  1. expression of LHR (show LHCGR Proteins) mRNA in bovine granulosa cells is established after follicle deviation, and the lower abundance of LRBP mRNA after the expected time of deviation may contribute to greater expression of LHR (show LHCGR Proteins) in the bovine dominant follicle

Mevalonate Kinase (MVK) Protein Profile

Protein Summary

This gene encodes the peroxisomal enzyme mevalonate kinase. Mevalonate is a key intermediate, and mevalonate kinase a key early enzyme, in isoprenoid and sterol synthesis. Mevalonate kinase deficiency caused by mutation of this gene results in mevalonic aciduria, a disease characterized psychomotor retardation, failure to thrive, hepatosplenomegaly, anemia and recurrent febrile crises. Defects in this gene also cause hyperimmunoglobulinaemia D and periodic fever syndrome, a disorder characterized by recurrent episodes of fever associated with lymphadenopathy, arthralgia, gastrointestinal dismay and skin rash. Two transcript variants that encode the same protein have been found for this gene.

Gene names and symbols associated with Mevalonate Kinase Proteins (MVK)

  • mevalonate kinase (MVK)
  • mevalonate kinase (MK)
  • mevalonate kinase (mvk)
  • mevalonate kinase (LMOf2365_0011)
  • mvk (mvk)
  • mevalonate kinase (Mmah_1549)
  • mevalonate kinase (Tagg_0317)
  • mevalonate kinase (Shell_0601)
  • mevalonate kinase (Mvol_0621)
  • mevalonate kinase (Igag_1464)
  • mevalonate kinase (Mpet_0759)
  • mevalonate kinase (Vdis_2290)
  • mevalonate kinase (Mfer_0895)
  • mevalonate kinase (Desmu_0298)
  • mevalonate kinase (Arcve_0599)
  • mevalonate kinase (Mzhil_1009)
  • mevalonate kinase (Mvk)
  • 2310010A05Rik protein
  • AI256848 protein
  • AI414037 protein
  • DDBDRAFT_0168621 protein
  • DDBDRAFT_0302479 protein
  • DDB_0168621 protein
  • DDB_0302479 protein
  • F21A20.160 protein
  • F21A20_160 protein
  • LRBP protein
  • mevalonate kinase protein
  • MK protein
  • MVK protein
  • MVLK protein
  • POROK3 protein
  • zgc:103473 protein

Protein level used designations for Mevalonate Kinase Proteins (MVK)

mevalonate kinase , LH receptor mRNA-binding protein , mevalonate kinase 1 , MK , mevalonate kinase (mevalonic aciduria)

GENE ID SPECIES
467175 Pan troglodytes
707645 Macaca mulatta
832804 Arabidopsis thaliana
1472494 Methanosarcina acetivorans C2A
1495443 Pyrococcus abyssi GE5
2798266 Listeria monocytogenes serotype 4b str. F2365
4465372 Listeria welshimeri serovar 6b str. SLCC5334
4798261 Lactococcus lactis subsp. cremoris MG1363
5144513 Methanocella arvoryzae MRE50
7080927 Listeria monocytogenes HCC23
7987447 Thermococcus gammatolerans EJ3
8618272 Dictyostelium discoideum AX4
8983723 Methanohalophilus mahii DSM 5219
9165330 Thermosphaera aggregans DSM 11486
9233890 Staphylothermus hellenicus DSM 12710
9275843 Methanococcus voltae A3
9716780 Ignisphaera aggregans DSM 17230
9743214 Methanoplanus petrolearius DSM 11571
9753245 Vulcanisaeta distributa DSM 14429
9962632 Methanothermus fervidus DSM 2088
10152990 Desulfurococcus mucosus DSM 2162
10393695 Archaeoglobus veneficus SNP6
10822632 Methanosalsum zhilinae DSM 4017
4598 Homo sapiens
17855 Mus musculus
81727 Rattus norvegicus
492477 Danio rerio
768555 Gallus gallus
505792 Bos taurus
486309 Canis lupus familiaris
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