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anti-Microphthalmia-Associated Transcription Factor (MITF) Antibodies

MITF encodes a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. Additionally we are shipping MITF Kits (12) and MITF Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
MITF 4286 O75030
MITF 17342 Q08874
MITF 25094  
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Top anti-MITF Antibodies at antibodies-online.com

Showing 10 out of 173 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-MITF Antibody Titration: 0.2-1 ug/mlPositive Control: Hela cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, FACS, IF, WB Flow cytometric analysis of K562 cells using  MITF Antibody (N-term) Cat.-No AP52701PU-N (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. Confocal immunofluorescent analysis of  MITF Antibody (N-term) Cat.-No AP52701PU-N with hela cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). Actin filaments have been labeled with Alexa Fluor 555 phalloidin (red). DAPI was used to stain the cell nuclear (blue). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-MITF Antibody Titration: 1.25ug/mlELISA Titer: 1:1562500Positive Control: HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Mouse Un-conjugated WB Western blot analysis of Mitf in A375 lysate using ABIN252517 at 4 ug/ml. Western Blot: MiTF Antibody (21D1418) [ABIN2525171] - Western blot analysis of HeLa lysate (35ug per lane, RIPA buffer) using MiTF antibody (ABIN2525171) at 0.1ug/ml. Band detected at ~60kDa. (Expected MW of 58.2kDa according to NP_937802.1). 0.1 mg Log in to see 5 to 7 Days
$408.19
Details
Human Mouse Un-conjugated EMSA, IHC (fro), IP, WB 0.1 mg Log in to see 6 to 8 Days
$665.50
Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IF, IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated ChIP, ICC, IF, IHC, WB 100 μL Log in to see 7 to 8 Days
$434.50
Details
Human Mouse Un-conjugated ChIPSeq, ChIP, EMSA, ICC, IF, IP, WB MITF antibody (mAb) tested by ChIP-Seq. (ChIP) was performed using the ChIP-IT® High Sensitivity Kit (Cat. No. 53040) and chromatin from a human melanoma cell line (2.5 million cells). ChIP DNA was sequenced on the Illumina GA II and 19 million sequence tags were mapped to identify MITF binding sites across the genome. The image shows hundreds of MITF binding sites across a 60 million bp region on chromosome 9. MITF antibody (mAb) tested by ChIP. Chromatin immunoprecipitation (ChIP) was performed using the ChIP-IT® High Sensitivity Kit (Cat. No. 53040) with 30 µg of chromatin from human lung melanoma cell line MALME-3M and 4 µg of MITF antibody. ChIP DNA was used in qPCR with the control primer pairs or gene-specific primer pairs as indicated. Data are presented as Binding Events Detected per 1000 Cells using Active Motif's Epigenetic Services normalization scheme which accounts for primer efficiency and the amount of chromatin used in the ChIP reaction. 100 μg Log in to see 1 to 2 Days
$507.50
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded mouse melanoma labeled with Anti- MITF Polyclonal Antibody, Unconjugated (ABIN676373) at 1:200 followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded mouse melanoma labeled with Anti- MITF Polyclonal Antibody, Unconjugated (ABIN676373) at 1:200 followed by conjugation to the secondary antibody Goat Anti-Rabbit IgG, PE conjugated used at 1:200 dilution for 40 minutes at 37°C and DAPI 100 μL Log in to see 3 to 7 Days
$269.50
Details

MITF Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-MITF Antibodies

  1. Human Monoclonal MITF Primary Antibody for ChIPSeq, ChIP - ABIN2668714 : Du, Miller, Widlund, Horstmann, Ramaswamy, Fisher: MLANA/MART1 and SILV/PMEL17/GP100 are transcriptionally regulated by MITF in melanocytes and melanoma. in The American journal of pathology 2003 (PubMed)
    Show all 3 references for ABIN2668714

  2. Human Polyclonal MITF Primary Antibody for ChIP, ICC - ABIN2452049 : Osawa, Egawa, Mak, Moriyama, Freter, Yonetani, Beermann, Nishikawa: Molecular characterization of melanocyte stem cells in their niche. in Development (Cambridge, England) 2005 (PubMed)
    Show all 3 references for ABIN2452049

  3. Human Monoclonal MITF Primary Antibody for EMSA, IHC (fro) - ABIN264430 : Hägglund, Berghard, Carlsson: Canonical Wnt/?-catenin signalling is essential for optic cup formation. in PLoS ONE 2013 (PubMed)
    Show all 2 references for ABIN264430

  4. Chicken Polyclonal MITF Primary Antibody for WB - ABIN2780333 : Park, Wu, Yonemoto, Murphy-Smith, Wu, Stachur, Gilchrest: MITF mediates cAMP-induced protein kinase C-beta expression in human melanocytes. in The Biochemical journal 2006 (PubMed)

  5. Human Polyclonal MITF Primary Antibody for EIA, FACS - ABIN953453 : Miller, Levy, Davis, Razin, Fisher: Sumoylation of MITF and its related family members TFE3 and TFEB. in The Journal of biological chemistry 2004 (PubMed)

  6. Human Monoclonal MITF Primary Antibody for WB - ABIN252517 : Lee, Jung, Lee, Huh, Boo, Hyun, Kim, Park: Mechanisms of melanogenesis inhibition by 2,5-dimethyl-4-hydroxy-3(2H)-furanone. in The British journal of dermatology 2007 (PubMed)

  7. Cow (Bovine) Polyclonal MITF Primary Antibody for WB - ABIN2777228 : Schartl, Wilde, Laisney, Taniguchi, Takeda, Meierjohann: A mutated EGFR is sufficient to induce malignant melanoma with genetic background-dependent histopathologies. in The Journal of investigative dermatology 2009 (PubMed)

  8. Chicken Polyclonal MITF Primary Antibody for WB - ABIN2780334 : Chiaverini, Beuret, Flori, Busca, Abbe, Bille, Bahadoran, Ortonne, Bertolotto, Ballotti: Microphthalmia-associated transcription factor regulates RAB27A gene expression and controls melanosome transport. in The Journal of biological chemistry 2008 (PubMed)

  9. Human Polyclonal MITF Primary Antibody for IF (p), IHC (p) - ABIN676373 : Han, Sung, Lee: Antimelanogenesis Activity of Hydrolyzed Ginseng Extract (GINST) via Inhibition of JNK Mitogen-activated Protein Kinase in B16F10 Cells. in Journal of food science 2016 (PubMed)

More Antibodies against MITF Interaction Partners

Horse (Equine) Microphthalmia-Associated Transcription Factor (MITF) interaction partners

  1. Accumulating mutations in series of haplotypes at the KIT and MITF loci are major determinants of white markings in Franches-Montagnes horses.

  2. several independent mutations in MITF and PAX3 (show PAX3 Antibodies) together with known variants in the EDNRB (show EDNRB Antibodies) and KIT genes explain a large proportion of horses with the more extreme white spotting phenotypes.

Human Microphthalmia-Associated Transcription Factor (MITF) interaction partners

  1. Our studies have established that the cooperative antiproliferative effects of aspirin and I3C in human melanoma cells trigger a significant downregulation of MITF-M gene expression and disruption of MITF-M promoter activity. results demonstrate that aspirin-regulated Wnt (show WNT2 Antibodies) signaling and I3C-targeted signaling pathways converge at distinct DNA elements in the MITF-M promoter to cooperatively disrupt MITF-M expression

  2. Addition of MITF>/=50% into the logistic regression analysis significantly improves the accuracy of the melanoma nomogram in prediction of regional nodal spread

  3. The MITF p.E318K mutation does not appear to play a major role in sporadic renal cell carcinoma (show MOK Antibodies) carcinogenesis, but is possibly restricted to a rare subpopulation of inherited renal cell carcinoma (show MOK Antibodies)

  4. Immunohistochemistry using D2-40 monoclonal antibody (MAGE2) and anti-MITF1 increased detection of lymphovascular invasion in primary cutaneous melanoma.

  5. Overexpression of MITF is associated with melanoma cell survival and progression.

  6. We conclude that the expression of Rlbp1 and Rdh5 critically depends on functional Mitf in the RPE and suggest that MITF has an important role in controlling retinoid processing in the RPE.

  7. A concomitant AURKA (show AURKA Antibodies)/BRAF (show BRAF Antibodies) and AURKA (show AURKA Antibodies)/MEK (show MAP2K1 Antibodies) targeting overcame MAPK (show MAPK1 Antibodies) signaling activation-associated resistance signature in BRAF (show BRAF Antibodies)- and NRAS (show NRAS Antibodies)-mutated melanomas, respectively, and elicited heightened anti-proliferative activity and apoptotic cell death.

  8. Results show that Mitf, probably including Mitf-M, is expressed in the mitral cells and tufted cells that transmit the information derived from olfactory sensory neurons to the olfactory cortex.

  9. SOX5 (show SOX5 Antibodies) has a strong inhibitory effect on MITF expression and seems to have a decisive clinical impact on melanoma during tumor progression.

  10. In addition to melanoma risk, MITF p.E318K is associated with a high nevi count and could play a role in fast-growing melanomas.

Mouse (Murine) Microphthalmia-Associated Transcription Factor (MITF) interaction partners

  1. Microphthalmia-associated transcription factor regulates skin melanoblast migration by repressing the melanoma cell adhesion molecule (show MCAM Antibodies)

  2. These findings demonstrate that LC3 (show MAP1LC3A Antibodies) contributes to melanogenesis by increasing ERK (show EPHB2 Antibodies)-dependent MITF expression, thereby providing a mechanistic insight into the signaling network that links autophagy to melanogenesis.

  3. the retinal degeneration associated with the disruption of the visual cycle in Mitf-deficient mice can be partially corrected both structurally and functionally by an exogenous supply of 9-cis-retina

  4. Results show that Mitf, probably including Mitf-M, is expressed in the mitral cells and tufted cells that transmit the information derived from olfactory sensory neurons to the olfactory cortex.

  5. Therefore, it is reasonable to assume that the increase in the expression of Mitf in melanocytes is involved in the age-ssociated increase in the pigmentation in the eyes of black-eyed mice.

  6. MITF interacts with BRG1 (show SMARCA4 Antibodies) to promote GATA4 (show GATA4 Antibodies) expression in cardiac hypertrophy.

  7. Overexpression of FHL2 (show FHL2 Antibodies) alone had no effect on Erbin (show ERBB2IP Antibodies) expression, but in the presence of MITF, Erbin (show ERBB2IP Antibodies) expression was decreased.

  8. A reciprocal antagonism between the MITF and c-Jun (show JUN Antibodies) interconnects inflammation-induced dedifferentiation with pro-inflammatory cytokine responsiveness of melanoma cells favouring myeloid cell recruitment.

  9. BPTF (show BPTF Antibodies) likely acts as a cofactor for other transcription factors in MITF-negative melanoma cells and there are clearly genes regulated by BPTF (show BPTF Antibodies), but not MITF, in MITF-expressing lines.

  10. the crucial role of signaling dependent MITF/p38 MAPK (show MAPK14 Antibodies) interactions in osteoclast differentiation

Cow (Bovine) Microphthalmia-Associated Transcription Factor (MITF) interaction partners

  1. Variability in the MITF gene clearly explained the differences between spotted and non-spotted cattle phenotypes but, at the same time, it is evident that this gene is not the only genetic factor determining piebaldism in two of the studied cattle breeds.

  2. The objectives of this study were to characterize the phenotypes of German White Fleckvieh and to identify the mutation responsible for this newly detected phenotype in cattle using genome-wide association analyses and re-sequencing of MITF.

Pig (Porcine) Microphthalmia-Associated Transcription Factor (MITF) interaction partners

  1. Although MITF does not seem to be the causal gene of the QTL initially observed, it can not be excluded that a prominent role of its transcription and function in the outbreak and evolution of the tumors observed in pigs.

MITF Antigen Profile

Protein Summary

This gene encodes a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. It regulates the differentiation and development of melanocytes retinal pigment epithelium and is also responsible for pigment cell-specific transcription of the melanogenesis enzyme genes. Heterozygous mutations in the this gene cause auditory-pigmentary syndromes, such as Waardenburg syndrome type 2 and Tietz syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.

Gene names and symbols associated with MITF

  • microphthalmia-associated transcription factor (MITF) antibody
  • microphthalmia-associated transcription factor (mitf) antibody
  • microphthalmia-associated transcription factor (LOC100313655) antibody
  • microphthalmia-associated transcription factor (mitf-b) antibody
  • microphthalmia-associated transcription factor (mitf-A) antibody
  • Microphthalmia (MICROP) antibody
  • microphthalmia-associated transcription factor (Mitf) antibody
  • BCC2 antibody
  • Bhlhe32 antibody
  • bw antibody
  • CMI9 antibody
  • CMM8 antibody
  • Gsfbcc2 antibody
  • LOC100313655 antibody
  • mi antibody
  • MITF antibody
  • MITF-A antibody
  • MITF-H antibody
  • MITF-M antibody
  • mitfa antibody
  • mitfb antibody
  • vit antibody
  • Vitiligo antibody
  • Wh antibody
  • WS2 antibody
  • WS2A antibody

Protein level used designations for MITF

microphthalmia transcription factor , microphthalmia-associated transcription factor , micophthalmia-associated transcription factor b , class E basic helix-loop-helix protein 32 , black eyed white , transcription factor , microphtalmia-associated transcription factor

GENE ID SPECIES
100033918 Equus caballus
460500 Pan troglodytes
100101790 Xenopus (Silurana) tropicalis
100313655 Saccoglossus kowalevskii
100337579 Xenopus laevis
100534525 Oreochromis niloticus
100599577 Nomascus leucogenys
100532953 Ovis aries
4286 Homo sapiens
17342 Mus musculus
25094 Rattus norvegicus
407219 Bos taurus
415126 Canis lupus familiaris
395886 Gallus gallus
414902 Sus scrofa
Selected quality suppliers for anti-MITF (MITF) Antibodies
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