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anti-Microphthalmia-Associated Transcription Factor (MITF) Antibodies

MITF encodes a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. Additionally we are shipping MITF Kits (11) and MITF Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
MITF 4286 O75030
MITF 17342 Q08874
MITF 25094  
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Top anti-MITF Antibodies at antibodies-online.com

Showing 10 out of 130 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-MITF Antibody Titration: 0.2-1 ug/mlPositive Control: Hela cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, FACS, IF, WB Flow cytometric analysis of K562 cells using  MITF Antibody (N-term) Cat.-No AP52701PU-N (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. Confocal immunofluorescent analysis of  MITF Antibody (N-term) Cat.-No AP52701PU-N with hela cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). Actin filaments have been labeled with Alexa Fluor 555 phalloidin (red). DAPI was used to stain the cell nuclear (blue). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-MITF Antibody Titration: 1.25ug/mlELISA Titer: 1:1562500Positive Control: HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Mouse Un-conjugated EMSA, IHC (fro), IP, WB 0.1 mg Log in to see 6 to 8 Days
$643.50
Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IF, IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated ChIP, ICC, IF, IHC, WB 100 μL Log in to see 7 to 8 Days
$434.50
Details
Human Mouse Un-conjugated ChIPSeq, ChIP, EMSA, ICC, IF, IP, WB MITF antibody (mAb) tested by ChIP-Seq. (ChIP) was performed using the ChIP-IT® High Sensitivity Kit (Cat. No. 53040) and chromatin from a human melanoma cell line (2.5 million cells). ChIP DNA was sequenced on the Illumina GA II and 19 million sequence tags were mapped to identify MITF binding sites across the genome. The image shows hundreds of MITF binding sites across a 60 million bp region on chromosome 9. MITF antibody (mAb) tested by ChIP. Chromatin immunoprecipitation (ChIP) was performed using the ChIP-IT® High Sensitivity Kit (Cat. No. 53040) with 30 µg of chromatin from human lung melanoma cell line MALME-3M and 4 µg of MITF antibody. ChIP DNA was used in qPCR with the control primer pairs or gene-specific primer pairs as indicated. Data are presented as Binding Events Detected per 1000 Cells using Active Motif's Epigenetic Services normalization scheme which accounts for primer efficiency and the amount of chromatin used in the ChIP reaction. 100 μg Log in to see 1 to 2 Days
$478.33
Details
Mouse Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from COS7 cells, using MITF (Phospho-Ser180/73) Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details

MITF Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-MITF Antibodies

  1. Human Polyclonal MITF Primary Antibody for ChIP, ICC - ABIN2452049 : Osawa, Egawa, Mak, Moriyama, Freter, Yonetani, Beermann, Nishikawa: Molecular characterization of melanocyte stem cells in their niche. in Development (Cambridge, England) 2005 (PubMed)
    Show all 3 references for ABIN2452049

  2. Human Monoclonal MITF Primary Antibody for ChIPSeq, ChIP - ABIN2668714 : Du, Miller, Widlund, Horstmann, Ramaswamy, Fisher: MLANA/MART1 and SILV/PMEL17/GP100 are transcriptionally regulated by MITF in melanocytes and melanoma. in The American journal of pathology 2003 (PubMed)
    Show all 3 references for ABIN2668714

  3. Human Monoclonal MITF Primary Antibody for EMSA, IHC (fro) - ABIN264430 : Hägglund, Berghard, Carlsson: Canonical Wnt/?-catenin signalling is essential for optic cup formation. in PLoS ONE 2013 (PubMed)
    Show all 2 references for ABIN264430

  4. Chicken Polyclonal MITF Primary Antibody for WB - ABIN2780334 : Chiaverini, Beuret, Flori, Busca, Abbe, Bille, Bahadoran, Ortonne, Bertolotto, Ballotti: Microphthalmia-associated transcription factor regulates RAB27A gene expression and controls melanosome transport. in The Journal of biological chemistry 2008 (PubMed)

  5. Cow (Bovine) Polyclonal MITF Primary Antibody for WB - ABIN2777228 : Schartl, Wilde, Laisney, Taniguchi, Takeda, Meierjohann: A mutated EGFR is sufficient to induce malignant melanoma with genetic background-dependent histopathologies. in The Journal of investigative dermatology 2009 (PubMed)

  6. Chicken Polyclonal MITF Primary Antibody for WB - ABIN2780333 : Park, Wu, Yonemoto, Murphy-Smith, Wu, Stachur, Gilchrest: MITF mediates cAMP-induced protein kinase C-beta expression in human melanocytes. in The Biochemical journal 2006 (PubMed)

  7. Human Polyclonal MITF Primary Antibody for EIA, FACS - ABIN953453 : Miller, Levy, Davis, Razin, Fisher: Sumoylation of MITF and its related family members TFE3 and TFEB. in The Journal of biological chemistry 2004 (PubMed)

More Antibodies against MITF Interaction Partners

Horse (Equine) Microphthalmia-Associated Transcription Factor (MITF) interaction partners

  1. Accumulating mutations in series of haplotypes at the KIT and MITF loci are major determinants of white markings in Franches-Montagnes horses.

  2. several independent mutations in MITF and PAX3 (show PAX3 Antibodies) together with known variants in the EDNRB (show EDNRB Antibodies) and KIT genes explain a large proportion of horses with the more extreme white spotting phenotypes.

Human Microphthalmia-Associated Transcription Factor (MITF) interaction partners

  1. Results show that Mitf, probably including Mitf-M, is expressed in the mitral cells and tufted cells that transmit the information derived from olfactory sensory neurons to the olfactory cortex.

  2. SOX5 (show SOX5 Antibodies) has a strong inhibitory effect on MITF expression and seems to have a decisive clinical impact on melanoma during tumor progression.

  3. In addition to melanoma risk, MITF p.E318K is associated with a high nevi count and could play a role in fast-growing melanomas.

  4. expression of the molecular marker Mitf in primary cutaneous melanomas is a useful tool in assessing lymph node status.

  5. an MITF-CEACAM1 (show CEACAM1 Antibodies) axis is suggested as a potential determinant of melanoma progression.

  6. LEF-1 (show LEF1 Antibodies) and MITF regulate tyrosinase (show TYR Antibodies) gene transcription in vitro via binding to its promoter.

  7. Here we show that MITF-A mRNA is predominantly expressed in all three human liver cancer cell lines examined.

  8. Data show that mutant microphthalmia-associated transcription factor (MITF) with loss of localization signals (NLS (show ALDH1A2 Antibodies)) has failed to transactivate the transcriptional activities of target gene tyrosinase (TYR (show TYR Antibodies)), which can cause Waardenburg syndrome.

  9. Data suggest that the heterozygous deletion mutation c.649_651delAGA in exon 7 of the microphthalmia-associated transcription factor (MITF) gene probably underlies the disease in the first family.

  10. A reciprocal antagonism between the MITF and c-Jun (show JUN Antibodies) interconnects inflammation-induced dedifferentiation with pro-inflammatory cytokine responsiveness of melanoma cells favouring myeloid cell recruitment.

Mouse (Murine) Microphthalmia-Associated Transcription Factor (MITF) interaction partners

  1. Results show that Mitf, probably including Mitf-M, is expressed in the mitral cells and tufted cells that transmit the information derived from olfactory sensory neurons to the olfactory cortex.

  2. Therefore, it is reasonable to assume that the increase in the expression of Mitf in melanocytes is involved in the age-ssociated increase in the pigmentation in the eyes of black-eyed mice.

  3. MITF interacts with BRG1 (show SMARCA4 Antibodies) to promote GATA4 (show GATA4 Antibodies) expression in cardiac hypertrophy.

  4. Overexpression of FHL2 (show FHL2 Antibodies) alone had no effect on Erbin (show ERBB2IP Antibodies) expression, but in the presence of MITF, Erbin (show ERBB2IP Antibodies) expression was decreased.

  5. A reciprocal antagonism between the MITF and c-Jun (show JUN Antibodies) interconnects inflammation-induced dedifferentiation with pro-inflammatory cytokine responsiveness of melanoma cells favouring myeloid cell recruitment.

  6. BPTF (show BPTF Antibodies) likely acts as a cofactor for other transcription factors in MITF-negative melanoma cells and there are clearly genes regulated by BPTF (show BPTF Antibodies), but not MITF, in MITF-expressing lines.

  7. the crucial role of signaling dependent MITF/p38 MAPK (show MAPK14 Antibodies) interactions in osteoclast differentiation

  8. HDAC7 (show HDAC7 Antibodies) in osteoclasts is an important molecular regulator of MITF activity and bone homeostasis.

  9. MITF-BRG1 (show SMARCA4 Antibodies) interplay thus plays an essential role in transcription regulation in melanoma.

  10. Expression of microRNA-211 is regulated by the key melanocyte transcription factor MITF and regulates pigmentation by targeting the TGF-beta (show TGFB1 Antibodies) receptor 2.

Cow (Bovine) Microphthalmia-Associated Transcription Factor (MITF) interaction partners

  1. Variability in the MITF gene clearly explained the differences between spotted and non-spotted cattle phenotypes but, at the same time, it is evident that this gene is not the only genetic factor determining piebaldism in two of the studied cattle breeds.

  2. The objectives of this study were to characterize the phenotypes of German White Fleckvieh and to identify the mutation responsible for this newly detected phenotype in cattle using genome-wide association analyses and re-sequencing of MITF.

Pig (Porcine) Microphthalmia-Associated Transcription Factor (MITF) interaction partners

  1. Although MITF does not seem to be the causal gene of the QTL initially observed, it can not be excluded that a prominent role of its transcription and function in the outbreak and evolution of the tumors observed in pigs.

MITF Antigen Profile

Protein Summary

This gene encodes a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. It regulates the differentiation and development of melanocytes retinal pigment epithelium and is also responsible for pigment cell-specific transcription of the melanogenesis enzyme genes. Heterozygous mutations in the this gene cause auditory-pigmentary syndromes, such as Waardenburg syndrome type 2 and Tietz syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.

Gene names and symbols associated with MITF

  • microphthalmia-associated transcription factor (MITF) antibody
  • microphthalmia-associated transcription factor (mitf) antibody
  • microphthalmia-associated transcription factor (LOC100313655) antibody
  • microphthalmia-associated transcription factor (mitf-b) antibody
  • microphthalmia-associated transcription factor (mitf-A) antibody
  • Microphthalmia (MICROP) antibody
  • microphthalmia-associated transcription factor (Mitf) antibody
  • BCC2 antibody
  • Bhlhe32 antibody
  • bw antibody
  • CMI9 antibody
  • CMM8 antibody
  • Gsfbcc2 antibody
  • LOC100313655 antibody
  • mi antibody
  • MITF antibody
  • MITF-A antibody
  • MITF-H antibody
  • MITF-M antibody
  • mitfa antibody
  • mitfb antibody
  • vit antibody
  • Vitiligo antibody
  • Wh antibody
  • WS2 antibody
  • WS2A antibody

Protein level used designations for MITF

microphthalmia transcription factor , microphthalmia-associated transcription factor , micophthalmia-associated transcription factor b , class E basic helix-loop-helix protein 32 , black eyed white , transcription factor , microphtalmia-associated transcription factor

GENE ID SPECIES
100033918 Equus caballus
460500 Pan troglodytes
100101790 Xenopus (Silurana) tropicalis
100313655 Saccoglossus kowalevskii
100337579 Xenopus laevis
100534525 Oreochromis niloticus
100599577 Nomascus leucogenys
100532953 Ovis aries
4286 Homo sapiens
17342 Mus musculus
25094 Rattus norvegicus
407219 Bos taurus
415126 Canis lupus familiaris
395886 Gallus gallus
414902 Sus scrofa
Selected quality suppliers for anti-MITF (MITF) Antibodies
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