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MITF encodes a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. Additionally we are shipping MITF Kits (12) and MITF Proteins (5) and many more products for this protein.
Showing 10 out of 173 products:
Human Monoclonal MITF Primary Antibody for ChIPSeq, ChIP - ABIN2668714
Du, Miller, Widlund, Horstmann, Ramaswamy, Fisher: MLANA/MART1 and SILV/PMEL17/GP100 are transcriptionally regulated by MITF in melanocytes and melanoma. in The American journal of pathology 2003
Show all 3 references for ABIN2668714
Human Polyclonal MITF Primary Antibody for ChIP, ICC - ABIN2452049
Osawa, Egawa, Mak, Moriyama, Freter, Yonetani, Beermann, Nishikawa: Molecular characterization of melanocyte stem cells in their niche. in Development (Cambridge, England) 2005
Show all 3 references for ABIN2452049
Human Monoclonal MITF Primary Antibody for EMSA, IHC (fro) - ABIN264430
Hägglund, Berghard, Carlsson: Canonical Wnt/?-catenin signalling is essential for optic cup formation. in PLoS ONE 2013
Show all 2 references for ABIN264430
Chicken Polyclonal MITF Primary Antibody for WB - ABIN2780333
Park, Wu, Yonemoto, Murphy-Smith, Wu, Stachur, Gilchrest: MITF mediates cAMP-induced protein kinase C-beta expression in human melanocytes. in The Biochemical journal 2006
Human Polyclonal MITF Primary Antibody for EIA, FACS - ABIN953453
Miller, Levy, Davis, Razin, Fisher: Sumoylation of MITF and its related family members TFE3 and TFEB. in The Journal of biological chemistry 2004
Human Monoclonal MITF Primary Antibody for WB - ABIN252517
Lee, Jung, Lee, Huh, Boo, Hyun, Kim, Park: Mechanisms of melanogenesis inhibition by 2,5-dimethyl-4-hydroxy-3(2H)-furanone. in The British journal of dermatology 2007
Cow (Bovine) Polyclonal MITF Primary Antibody for WB - ABIN2777228
Schartl, Wilde, Laisney, Taniguchi, Takeda, Meierjohann: A mutated EGFR is sufficient to induce malignant melanoma with genetic background-dependent histopathologies. in The Journal of investigative dermatology 2009
Chicken Polyclonal MITF Primary Antibody for WB - ABIN2780334
Chiaverini, Beuret, Flori, Busca, Abbe, Bille, Bahadoran, Ortonne, Bertolotto, Ballotti: Microphthalmia-associated transcription factor regulates RAB27A gene expression and controls melanosome transport. in The Journal of biological chemistry 2008
Human Polyclonal MITF Primary Antibody for IF (p), IHC (p) - ABIN676373
Han, Sung, Lee: Antimelanogenesis Activity of Hydrolyzed Ginseng Extract (GINST) via Inhibition of JNK Mitogen-activated Protein Kinase in B16F10 Cells. in Journal of food science 2016
Accumulating mutations in series of haplotypes at the KIT and MITF loci are major determinants of white markings in Franches-Montagnes horses.
several independent mutations in MITF and PAX3 (show PAX3 Antibodies) together with known variants in the EDNRB (show EDNRB Antibodies) and KIT genes explain a large proportion of horses with the more extreme white spotting phenotypes.
Our studies have established that the cooperative antiproliferative effects of aspirin and I3C in human melanoma cells trigger a significant downregulation of MITF-M gene expression and disruption of MITF-M promoter activity. results demonstrate that aspirin-regulated Wnt (show WNT2 Antibodies) signaling and I3C-targeted signaling pathways converge at distinct DNA elements in the MITF-M promoter to cooperatively disrupt MITF-M expression
Addition of MITF>/=50% into the logistic regression analysis significantly improves the accuracy of the melanoma nomogram in prediction of regional nodal spread
The MITF p.E318K mutation does not appear to play a major role in sporadic renal cell carcinoma (show MOK Antibodies) carcinogenesis, but is possibly restricted to a rare subpopulation of inherited renal cell carcinoma (show MOK Antibodies)
Immunohistochemistry using D2-40 monoclonal antibody (MAGE2) and anti-MITF1 increased detection of lymphovascular invasion in primary cutaneous melanoma.
Overexpression of MITF is associated with melanoma cell survival and progression.
We conclude that the expression of Rlbp1 and Rdh5 critically depends on functional Mitf in the RPE and suggest that MITF has an important role in controlling retinoid processing in the RPE.
A concomitant AURKA (show AURKA Antibodies)/BRAF (show BRAF Antibodies) and AURKA (show AURKA Antibodies)/MEK (show MAP2K1 Antibodies) targeting overcame MAPK (show MAPK1 Antibodies) signaling activation-associated resistance signature in BRAF (show BRAF Antibodies)- and NRAS (show NRAS Antibodies)-mutated melanomas, respectively, and elicited heightened anti-proliferative activity and apoptotic cell death.
Results show that Mitf, probably including Mitf-M, is expressed in the mitral cells and tufted cells that transmit the information derived from olfactory sensory neurons to the olfactory cortex.
SOX5 (show SOX5 Antibodies) has a strong inhibitory effect on MITF expression and seems to have a decisive clinical impact on melanoma during tumor progression.
In addition to melanoma risk, MITF p.E318K is associated with a high nevi count and could play a role in fast-growing melanomas.
Microphthalmia-associated transcription factor regulates skin melanoblast migration by repressing the melanoma cell adhesion molecule (show MCAM Antibodies)
These findings demonstrate that LC3 (show MAP1LC3A Antibodies) contributes to melanogenesis by increasing ERK (show EPHB2 Antibodies)-dependent MITF expression, thereby providing a mechanistic insight into the signaling network that links autophagy to melanogenesis.
the retinal degeneration associated with the disruption of the visual cycle in Mitf-deficient mice can be partially corrected both structurally and functionally by an exogenous supply of 9-cis-retina
Therefore, it is reasonable to assume that the increase in the expression of Mitf in melanocytes is involved in the age-ssociated increase in the pigmentation in the eyes of black-eyed mice.
MITF interacts with BRG1 (show SMARCA4 Antibodies) to promote GATA4 (show GATA4 Antibodies) expression in cardiac hypertrophy.
Overexpression of FHL2 (show FHL2 Antibodies) alone had no effect on Erbin (show ERBB2IP Antibodies) expression, but in the presence of MITF, Erbin (show ERBB2IP Antibodies) expression was decreased.
A reciprocal antagonism between the MITF and c-Jun (show JUN Antibodies) interconnects inflammation-induced dedifferentiation with pro-inflammatory cytokine responsiveness of melanoma cells favouring myeloid cell recruitment.
BPTF (show BPTF Antibodies) likely acts as a cofactor for other transcription factors in MITF-negative melanoma cells and there are clearly genes regulated by BPTF (show BPTF Antibodies), but not MITF, in MITF-expressing lines.
the crucial role of signaling dependent MITF/p38 MAPK (show MAPK14 Antibodies) interactions in osteoclast differentiation
Variability in the MITF gene clearly explained the differences between spotted and non-spotted cattle phenotypes but, at the same time, it is evident that this gene is not the only genetic factor determining piebaldism in two of the studied cattle breeds.
The objectives of this study were to characterize the phenotypes of German White Fleckvieh and to identify the mutation responsible for this newly detected phenotype in cattle using genome-wide association analyses and re-sequencing of MITF.
Although MITF does not seem to be the causal gene of the QTL initially observed, it can not be excluded that a prominent role of its transcription and function in the outbreak and evolution of the tumors observed in pigs.
This gene encodes a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. It regulates the differentiation and development of melanocytes retinal pigment epithelium and is also responsible for pigment cell-specific transcription of the melanogenesis enzyme genes. Heterozygous mutations in the this gene cause auditory-pigmentary syndromes, such as Waardenburg syndrome type 2 and Tietz syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.
microphthalmia transcription factor
, microphthalmia-associated transcription factor
, micophthalmia-associated transcription factor b
, class E basic helix-loop-helix protein 32
, black eyed white
, transcription factor
, microphtalmia-associated transcription factor