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Microtubule Associated Monoxygenase, Calponin and LIM Domain Containing 1 Proteins (MICAL1)

Monooxygenase that promotes depolymerization of F-actin by mediating oxidation of specific methionine residues on actin. Additionally we are shipping MICAL1 Antibodies (59) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
MICAL1 64780 Q8TDZ2
MICAL1 171580 Q8VDP3
Rat MICAL1 MICAL1 294520 D3ZBP4
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Top MICAL1 Proteins at antibodies-online.com

Showing 4 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

MICAL1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

More Proteins for Microtubule Associated Monoxygenase, Calponin and LIM Domain Containing 1 (MICAL1) Interaction Partners

Human Microtubule Associated Monoxygenase, Calponin and LIM Domain Containing 1 (MICAL1) interaction partners

  1. Data suggest that Sema6A (show SEMA6A Proteins) and Mical1 may represent new potential therapeutic targets in BRAFV600E melanoma.

  2. The MICAL1 directly induce oxidation of actin molecules, leading to actin depolymerization. ROS (show ROS1 Proteins) production by MICAL1 also causes oxidation of collapsin response mediator protein-2 (show DPYSL2 Proteins) which subsequently undergoes phosphorylation.

  3. although MICAL1 is auto-inhibited by its C-terminal coiled-coil region, MICAL2 remains constitutively active and affects stress fibers, suggesting differential but complementary roles for MICAL1 and MICAL2 in actin microfilament regulation

  4. Faint and scattered immunoreactivity for Mical-1 is observed in neurons of the neocortex of the temporal lobe epilepsy group, while strong immunoreactivity for Mical-1 is shown in control subjects.

  5. Findings show a biological role for MICAL-1 in apoptosis and define a novel negative regulatory mechanism of MST (show MAP3K10 Proteins)-NDR (show STK38 Proteins) signaling.

  6. a CasL interacting molecule that associates with vimentin (show VIM Proteins)

  7. MICAL-1 isoforms with their multidomain structure are novel rab1 (show RAB1A Proteins) interacting proteins that function as scaffold proteins connecting different components in the cell.

  8. The unfolding of MICAL-1 calpolnin homology (CH) domain was studied.

Mouse (Murine) Microtubule Associated Monoxygenase, Calponin and LIM Domain Containing 1 (MICAL1) interaction partners

  1. MICAL-1 regulates the targeting of secretory vesicles containing immunoglobulin superfamily cell adhesion molecules (IgCAMs) to the neuronal growth cone membrane through its ability to control the actin cytoskeleton using redox chemistry.

  2. Findings show a biological role for MICAL-1 in apoptosis and define a novel negative regulatory mechanism of MST (show MSTO1 Proteins)-NDR (show STK38 Proteins) signaling.

MICAL1 Protein Profile

Protein Summary

Monooxygenase that promotes depolymerization of F-actin by mediating oxidation of specific methionine residues on actin. Acts by modifying actin subunits through the addition of oxygen to form methionine-sulfoxide, leading to promote actin filament severing and prevent repolymerization. Acts as a cytoskeletal regulator that connects NEDD9 to intermediate filaments. Also acts as a negative regulator of apoptosis via its interaction with STK38 and STK38L\; acts by antagonizing STK38 and STK38L activation by MST1/STK4 (By similarity).

Gene names and symbols associated with MICAL1

  • microtubule associated monoxygenase, calponin and LIM domain containing 1 (MICAL1)
  • microtubule associated monoxygenase, calponin and LIM domain containing 1 (LOC100232670)
  • microtubule associated monooxygenase, calponin and LIM domain containing 1 (MICAL1)
  • microtubule associated monooxygenase, calponin and LIM domain containing 1 (Mical1)
  • microtubule associated monooxygenase, calponin and LIM domain containing 1 (mical1)
  • MICAL protein
  • MICAL-1 protein
  • Nical protein
  • zgc:171928 protein

Protein level used designations for MICAL1

microtubule associated monoxygenase, calponin and LIM domain containing 1 , CasL interacting molecule , NEDD9 interacting protein with calponin homology and LIM domains , NEDD9-interacting protein with calponin homology and LIM domains , molecule interacting with CasL protein 1 , protein-methionine sulfoxide oxidase MICAL1 , CasL interacting molecule MICAL , molecule interacting with CasL 1 , microtubule associated monooxygenase, calponin and LIM domain containing 1

GENE ID SPECIES
100066627 Equus caballus
100232670 Taeniopygia guttata
64780 Homo sapiens
171580 Mus musculus
294520 Rattus norvegicus
568573 Danio rerio
100153346 Sus scrofa
508306 Bos taurus
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