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Microtubule-Associated Protein, RP/EB Family, Member 1 Proteins (MAPRE1)

The protein encoded by MAPRE1 was first identified by its binding to the APC protein which is often mutated in familial and sporadic forms of colorectal cancer. Additionally we are shipping MAPRE1 Antibodies (53) and MAPRE1 Kits (8) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
MAPRE1 13589 Q61166
MAPRE1 114764 Q66HR2
MAPRE1 22919 Q15691
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Top MAPRE1 Proteins at antibodies-online.com

Showing 10 out of 12 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 7 to 8 Days
$319.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,693.17
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,693.17
Details
Yeast Xenopus tropicalis His tag   1 mg Log in to see 56 to 66 Days
$2,700.50
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 3 to 4 Days
$364.64
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details
Human Un-conjugated   20 μg Log in to see 6 Days
$285.21
Details

MAPRE1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Rat (Rattus)

Human , ,
,

Top referenced MAPRE1 Proteins

  1. Human MAPRE1 Protein expressed in Escherichia coli (E. coli) - ABIN667310 : Tirnauer, Grego, Salmon, Mitchison: EB1-microtubule interactions in Xenopus egg extracts: role of EB1 in microtubule stabilization and mechanisms of targeting to microtubules. in Molecular biology of the cell 2002 (PubMed)
    Show all 2 references for ABIN667310

More Proteins for Microtubule-Associated Protein, RP/EB Family, Member 1 (MAPRE1) Interaction Partners

Xenopus laevis Microtubule-Associated Protein, RP/EB Family, Member 1 (MAPRE1) interaction partners

  1. the Amer2 (show AMER2 Proteins)-EB1-APC (show APC Proteins) complex regulates cell migration by altering microtubule stability.

Pig (Porcine) Microtubule-Associated Protein, RP/EB Family, Member 1 (MAPRE1) interaction partners

  1. EB1-tubulin (show TUBB Proteins) interactions are mediated in part by the same tubulin (show TUBB Proteins) acidic tails utilized by other MAPs

Mouse (Murine) Microtubule-Associated Protein, RP/EB Family, Member 1 (MAPRE1) interaction partners

  1. Crosstalk between EB1 protein and Ankyrin-G is decisive for axon initial segment assembly.

  2. We describe here a novel function for tau as a direct regulator of eb1 and eb2 (show MAPRE2 Proteins) proteins in differentiating neuronal cells

  3. Data indicate that cortactin (show CTTN Proteins) as an Src (show SRC Proteins)-dependent interacting partner of EB1.

  4. Data indicate that EB1(MAPRE1) is up-regulated in osteoblasts and is required for bone cell differentiation.

  5. MAP1B interacts directly with EB1 and EB3 (show MAPRE3 Proteins) (EBs), two core 'microtubule plus-end tracking proteins' ( TIPs), and sequesters them in the cytosol of developing neuronal cells.

  6. the Amer2 (show AMER2 Proteins)-EB1-APC (show APC Proteins) complex regulates cell migration by altering microtubule stability.

  7. Detyrosination regulates CAP-Gly proteins interaction with alpha-tubulin (show TUBA4A Proteins), but not with EB1.

  8. End binding protein 1 is required for single-cell polarization and directional cell motility.

  9. These findings support a model where EB1 protein links microtubules to actin protrusion and cell polarity through signaling pathways involving PKC.

  10. results show an evolutionarily conserved pathway for microtubule capture, and suggest that mDia functions as a scaffold protein (show HOMER1 Proteins) for EB1 and APC (show APC Proteins) to stabilize microtubules and promote cell migration.

Human Microtubule-Associated Protein, RP/EB Family, Member 1 (MAPRE1) interaction partners

  1. We propose a novel mechanism by which ATIP3-EB1 (show MAPRE2 Proteins) interaction indirectly reduces the kinetics of EB1 (show MAPRE2 Proteins) exchange on its recognition site, thereby accounting for negative regulation of microtubule dynamic instability

  2. MAPRE1 can contribute to the detection of early-stage colorectal cancer and adenomas together with other biomarkers

  3. The authors show that the microtubule binding protein EB1 (end-binding protein 1), a key regulator of microtubule dynamics, can bind directly to filamentous actin (F-actin) F-actin.

  4. A previously uncharacterized EB1 (show MAPRE2 Proteins) linker region tracks microtubule plus ends in live cells.

  5. We find that the presence of EB1 (show MAPRE2 Proteins) can stiffen microtubules in a manner that depends on the hydrolysis state of the tubulin (show TUBB Proteins)-bound nucleotide

  6. The functions of EB1 (show MAPRE2 Proteins) in the regulation of microtubule dynamics and recruitment of other +TIPs, as well as the dimerization of EB1 (show MAPRE2 Proteins), undergo exquisite control by phosphorylation.

  7. TTBK2 bound EB1 and Cep164 through its SxIP motifs and a proline-rich motif, respectively.

  8. We showed for the first time that EB1 (show MAPRE2 Proteins) associates with microtubules in a phosphorylation-dependent manner, under control of reactive oxygen species

  9. EB1 (show MAPRE2 Proteins) has a role in linking AIM2 (show AIM2 Proteins) inflammasomes with autophagy-dependent secretion

  10. Aptamers binding to human EB1 (show MAPRE2 Proteins) and EB3 (show MAPRE3 Proteins), which have sequence requirements similar to but distinct from each other and from Drosophila EB1 (show MAPRE2 Proteins), were identified.

MAPRE1 Protein Profile

Protein Summary

The protein encoded by this gene was first identified by its binding to the APC protein which is often mutated in familial and sporadic forms of colorectal cancer. This protein localizes to microtubules, especially the growing ends, in interphase cells. During mitosis, the protein is associated with the centrosomes and spindle microtubules. The protein also associates with components of the dynactin complex and the intermediate chain of cytoplasmic dynein. Because of these associations, it is thought that this protein is involved in the regulation of microtubule structures and chromosome stability. This gene is a member of the RP/EB family.

Gene names and symbols associated with MAPRE1

  • microtubule-associated protein, RP/EB family, member 1a (mapre1a)
  • microtubule-associated protein, RP/EB family, member 1b (mapre1b)
  • microtubule-associated protein, RP/EB family, member 1 (mapre1)
  • microtubule-associated protein, RP/EB family, member 1 (MAPRE1)
  • microtubule-associated protein, RP/EB family, member 1 (Mapre1)
  • 5530600P05Rik protein
  • AI462499 protein
  • AI504412 protein
  • AW260097 protein
  • BIM1p protein
  • D2Ertd459e protein
  • EB1 protein
  • mapre1 protein
  • mapre1l protein
  • Mapre3 protein
  • MGC52508 protein
  • wu:fa01e12 protein
  • wu:fc23e11 protein
  • wu:fi33c06 protein
  • xEB1B protein
  • zgc:55428 protein
  • zgc:77807 protein
  • zgc:85755 protein

Protein level used designations for MAPRE1

microtubule-associated protein, RP/EB family, member 1 , microtubule-associated protein, RP/EB family, member 1, like , microtubule-associated protein RP/EB family member 1 , APC-binding protein EB1 , EB1 , end-binding protein 1 , adenomatosis polyposis coli binding protein Eb1 , adenomatous polyposis coli-binding protein EB1

GENE ID SPECIES
334135 Danio rerio
334728 Danio rerio
380590 Xenopus laevis
398293 Xenopus laevis
608797 Canis lupus familiaris
733687 Sus scrofa
100173206 Pongo abelii
13589 Mus musculus
114764 Rattus norvegicus
22919 Homo sapiens
507845 Bos taurus
419288 Gallus gallus
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