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Microtubule-Associated Protein, RP/EB Family, Member 2 (MAPRE2) ELISA Kits

The protein encoded by MAPRE2 shares significant homology to the adenomatous polyposis coli (APC) protein-binding EB1 gene family. Additionally we are shipping Microtubule-Associated Protein, RP/EB Family, Member 2 Antibodies (103) and Microtubule-Associated Protein, RP/EB Family, Member 2 Proteins (10) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human MAPRE2 MAPRE2 10982 Q15555
Anti-Mouse MAPRE2 MAPRE2 212307 Q8R001
Anti-Rat MAPRE2 MAPRE2 679221 Q3B8Q0
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More ELISA Kits for Microtubule-Associated Protein, RP/EB Family, Member 2 Interaction Partners

Human Microtubule-Associated Protein, RP/EB Family, Member 2 (MAPRE2) interaction partners

  1. Aurora B (show AURKB ELISA Kits) and CDK1 (show CDK1 ELISA Kits) temporally regulate the binding affinity of EB2 for microtubules, thereby ensuring kinetochore microtubule dynamics, proper mitotic progression and genome stability.

  2. Mutations in either TUBB (show TUBB2A ELISA Kits) or MAPRE2 cause circumferential skin creases Kunze type.

  3. EB2 is evidently important for initial microtubule reorganisation during epithelial polarisation, whereas its downregulation facilitates EB1 and ACF7 microtubule lattice association, microtubule-actin filament co-alignment and bundle formation.

  4. results suggest that EB1 and ClipCG12 act cooperatively to regulate microtubule dynamics (EB1)

  5. heterodimer formation between EB1 and EB3 (show MAPRE3 ELISA Kits), but not between EB2 and the other two EBs, occurs both in vitro and in cells as revealed by live cell imaging

  6. Data suggest that a functional interaction between EB1 and p150(Glued (show DCTN1 ELISA Kits)) is required for microtubule minus end anchoring at centrosomes during the assembly and maintenance of a radial microtubule array.

  7. EB1 may modulate kinetochore microtubule polymerization and/or attachment

  8. results support the novel hypothesis that EB1 overexpression may play a role in the development of esophageal squamous cell carcinoma by affecting APC (show APC ELISA Kits) function and activating the beta-catenin (show CTNNB1 ELISA Kits)/TCF (show HNF4A ELISA Kits) pathway

  9. Impaired EB1 or APC (show APC ELISA Kits) function generates lesions invisible to the spindle checkpoint and thereby promotes low levels of chromosomal loss (CIN (show PDXP ELISA Kits)) expected to fuel aneuploidy and possibly tumorigenesis.

  10. These data demonstrate that the COP9 (show COPS8 ELISA Kits) signalosome-dependent protection of EB1 is important for microtubule function.

Mouse (Murine) Microtubule-Associated Protein, RP/EB Family, Member 2 (MAPRE2) interaction partners

  1. Knockdown of HAX1 (show HAX1 ELISA Kits) and EB2 in skin epidermal cells stabilizes focal adhesions and impairs epidermal migration.

  2. Thus, we suggest that EB1 (show MAPRE1 ELISA Kits) could complement MAP1B (show MAP1B ELISA Kits) function during neural development.

Microtubule-Associated Protein, RP/EB Family, Member 2 (MAPRE2) Antigen Profile

Antigen Summary

The protein encoded by this gene shares significant homology to the adenomatous polyposis coli (APC) protein-binding EB1 gene family. This protein is a microtubule-associated protein that is necessary for spindle symmetry during mitosis. It is thought to play a role in the tumorigenesis of colorectal cancers and the proliferative control of normal cells. Alternative splicing of this gene results in multiple transcript variants.

Gene names and symbols associated with MAPRE2

  • microtubule-associated protein, RP/EB family, member 2 (MAPRE2) antibody
  • microtubule-associated protein, RP/EB family, member 2 (LOC100227855) antibody
  • microtubule-associated protein, RP/EB family, member 2 (Mapre2) antibody
  • microtubule-associated protein, RP/EB family, member 2 (mapre2) antibody
  • AI314113 antibody
  • C820009F03Rik antibody
  • D18Abb1e antibody
  • DKFZp459O163 antibody
  • EB1 antibody
  • EB2 antibody
  • MAPRE2 antibody
  • mapre2-A antibody
  • RP1 antibody

Protein level used designations for MAPRE2

microtubule-associated protein, RP/EB family, member 2 , Microtubule-associated protein RP/EB family member 2 , APC-binding protein EB1 , APC-binding protein EB2 , T-cell activation protein, EB1 family , end-binding protein 2 , microtubule-associated protein RP/EB family member 2 , T-cell activation protein, EB1 family, member 2

GENE ID SPECIES
455369 Pan troglodytes
100173979 Pongo abelii
100227855 Taeniopygia guttata
10982 Homo sapiens
212307 Mus musculus
679221 Rattus norvegicus
510159 Bos taurus
421105 Gallus gallus
490487 Canis lupus familiaris
373805 Xenopus laevis
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