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Microtubule-Associated Protein, RP/EB Family, Member 2 Proteins (MAPRE2)

The protein encoded by MAPRE2 shares significant homology to the adenomatous polyposis coli (APC) protein-binding EB1 gene family. Additionally we are shipping Microtubule-Associated Protein, RP/EB Family, Member 2 Antibodies (106) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
MAPRE2 10982 Q15555
MAPRE2 212307 Q8R001
MAPRE2 679221 Q3B8Q0
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Top Microtubule-Associated Protein, RP/EB Family, Member 2 Proteins at antibodies-online.com

Showing 9 out of 10 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 7 to 8 Days
$319.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,876.50
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,876.50
Details
Yeast Xenopus laevis His tag   1 mg Log in to see 56 to 66 Days
$2,880.17
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 3 to 4 Days
$382.86
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

MAPRE2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

Rat (Rattus)

Top referenced Microtubule-Associated Protein, RP/EB Family, Member 2 Proteins

  1. Human MAPRE2 Protein expressed in Escherichia coli (E. coli) - ABIN667560 : Bu, Su: Characterization of functional domains of human EB1 family proteins. in The Journal of biological chemistry 2003 (PubMed)

More Proteins for Microtubule-Associated Protein, RP/EB Family, Member 2 (MAPRE2) Interaction Partners

Human Microtubule-Associated Protein, RP/EB Family, Member 2 (MAPRE2) interaction partners

  1. Aurora B (show AURKB Proteins) and CDK1 (show CDK1 Proteins) temporally regulate the binding affinity of EB2 for microtubules, thereby ensuring kinetochore microtubule dynamics, proper mitotic progression and genome stability.

  2. Mutations in either TUBB (show TUBB2A Proteins) or MAPRE2 cause circumferential skin creases Kunze type.

  3. EB2 is evidently important for initial microtubule reorganisation during epithelial polarisation, whereas its downregulation facilitates EB1 and ACF7 microtubule lattice association, microtubule-actin filament co-alignment and bundle formation.

  4. results suggest that EB1 and ClipCG12 act cooperatively to regulate microtubule dynamics (EB1)

  5. heterodimer formation between EB1 and EB3 (show MAPRE3 Proteins), but not between EB2 and the other two EBs, occurs both in vitro and in cells as revealed by live cell imaging

  6. Data suggest that a functional interaction between EB1 and p150(Glued (show DCTN1 Proteins)) is required for microtubule minus end anchoring at centrosomes during the assembly and maintenance of a radial microtubule array.

  7. EB1 may modulate kinetochore microtubule polymerization and/or attachment

  8. results support the novel hypothesis that EB1 overexpression may play a role in the development of esophageal squamous cell carcinoma by affecting APC (show APC Proteins) function and activating the beta-catenin (show CTNNB1 Proteins)/TCF (show HNF4A Proteins) pathway

  9. Impaired EB1 or APC (show APC Proteins) function generates lesions invisible to the spindle checkpoint and thereby promotes low levels of chromosomal loss (CIN (show PDXP Proteins)) expected to fuel aneuploidy and possibly tumorigenesis.

  10. These data demonstrate that the COP9 (show COPS8 Proteins) signalosome-dependent protection of EB1 is important for microtubule function.

Mouse (Murine) Microtubule-Associated Protein, RP/EB Family, Member 2 (MAPRE2) interaction partners

  1. Knockdown of HAX1 (show HAX1 Proteins) and EB2 in skin epidermal cells stabilizes focal adhesions and impairs epidermal migration.

  2. Thus, we suggest that EB1 could complement MAP1B function during neural development.

Microtubule-Associated Protein, RP/EB Family, Member 2 (MAPRE2) Protein Profile

Protein Summary

The protein encoded by this gene shares significant homology to the adenomatous polyposis coli (APC) protein-binding EB1 gene family. This protein is a microtubule-associated protein that is necessary for spindle symmetry during mitosis. It is thought to play a role in the tumorigenesis of colorectal cancers and the proliferative control of normal cells. Alternative splicing of this gene results in multiple transcript variants.

Gene names and symbols associated with MAPRE2

  • microtubule-associated protein, RP/EB family, member 2 (MAPRE2)
  • microtubule-associated protein, RP/EB family, member 2 (LOC100227855)
  • microtubule-associated protein, RP/EB family, member 2 (Mapre2)
  • microtubule-associated protein, RP/EB family, member 2 (mapre2)
  • AI314113 protein
  • C820009F03Rik protein
  • D18Abb1e protein
  • DKFZp459O163 protein
  • EB1 protein
  • EB2 protein
  • MAPRE2 protein
  • mapre2-A protein
  • RP1 protein

Protein level used designations for MAPRE2

microtubule-associated protein, RP/EB family, member 2 , Microtubule-associated protein RP/EB family member 2 , APC-binding protein EB1 , APC-binding protein EB2 , T-cell activation protein, EB1 family , end-binding protein 2 , microtubule-associated protein RP/EB family member 2 , T-cell activation protein, EB1 family, member 2

GENE ID SPECIES
455369 Pan troglodytes
100173979 Pongo abelii
100227855 Taeniopygia guttata
10982 Homo sapiens
212307 Mus musculus
679221 Rattus norvegicus
510159 Bos taurus
421105 Gallus gallus
490487 Canis lupus familiaris
373805 Xenopus laevis
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