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Binds to the plus end of microtubules and regulates the dynamics of the microtubule cytoskeleton. Additionally we are shipping Microtubule-Associated Protein, RP/EB Family, Member 3 Antibodies (61) and Microtubule-Associated Protein, RP/EB Family, Member 3 Proteins (12) and many more products for this protein.
Aptamers binding to human EB1 (show MAPRE2 ELISA Kits) and EB3, which have sequence requirements similar to but distinct from each other and from Drosophila EB1 (show MAPRE2 ELISA Kits), were identified.
EB1 (show MAPRE2 ELISA Kits) and EB3 proteins are obligatory dimers.
Findings suggest that methylation-associated down-regulation of EBF3 and IRX1 (show IRX3 ELISA Kits) genes may play an important role in a pathogenic effect of TGF-beta (show TGFB1 ELISA Kits) on RASFs.
Daughter cell adhesion and cytokinesis completion are spatially regulated by distinct states of EB3 phosphorylation on serine 176 by Aurora B (show AURKB ELISA Kits).
decreasing the drebrin E (show DBN1 ELISA Kits) levels disrupted the normal subapical F-actin-myosin-IIB (show MYH10 ELISA Kits)-betaII-spectrin network and the apical accumulation of EB3, a microtubule-plus-end-binding protein
VE-cadherin (show CDH5 ELISA Kits) outside-in signaling regulates cytosolic calcium homeostasis and EB3 phosphorylation.
Data indicated that EB1 (show MAPRE2 ELISA Kits) and EB3 interact with proteins implicated in MT minus-end anchoring or vesicular trafficking to the cilia base, suggesting that EB1 (show MAPRE2 ELISA Kits) and EB3 promote ciliogenesis by facilitating such trafficking.
study found a polycytosine repeat (C8) in exon 5 of MAPRE3 that could be a potential mutation target in cancers with microsatellite instability (MSI (show MSI1 ELISA Kits)); found that the C8 is frequently mutated in gastric and colorectal carcinomas with MSI (show MSI1 ELISA Kits)
heterodimer formation between EB1 (show MAPRE2 ELISA Kits) and EB3, but not between EB2 (show MAPRE2 ELISA Kits) and the other two EBs, occurs both in vitro and in cells as revealed by live cell imaging
neither APC (show APC ELISA Kits) nor p150glued (show DCTN1 ELISA Kits) binding domain is necessary for EB1 (show MAPRE2 ELISA Kits) or EBF3 to induce microtubule bundling
EB3 binds to IP3 receptors, promotes IP3R (show ITPR1 ELISA Kits) clustering and Ca2 (show CA2 ELISA Kits)+ signals in endothelial cells.
MAP1B (show MAP1B ELISA Kits) interacts directly with EB1 (show MAPRE1 ELISA Kits) and EB3 (EBs), two core 'microtubule plus-end tracking proteins' ( TIPs), and sequesters them in the cytosol of developing neuronal cells.
DDA3 (show PSRC1 ELISA Kits) is a novel microtubule-associated protein (show SPAG5 ELISA Kits) that binds to EB3, and results implicate DDA3 (show PSRC1 ELISA Kits) and EB3 in the beta-catenin (show CTNNB1 ELISA Kits)-mediated growth signaling.
Two +TIPs, CLIP-170 (show CLIP1 ELISA Kits) and end-binding protein 3 (EB3), turn over rapidly on MT ends. Diffusion of CLIP-170 (show CLIP1 ELISA Kits) and EB3 appears to be rate limiting for their binding to MT plus ends.
Binds to the plus end of microtubules and regulates the dynamics of the microtubule cytoskeleton. Promotes microtubule growth. May be involved in spindle function by stabilizing microtubules and anchoring them at centrosomes. May play a role in cell migration (By similarity).
microtubule-associated protein, RP/EB family, member 3
, APC binding protein
, EB1 protein family member 3
, end-binding protein 3
, microtubule-associated protein RP/EB family member 3