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Microtubule-Associated Protein 1 Light Chain 3 alpha Proteins (MAP1LC3A)

MAP1A and MAP1B are microtubule-associated proteins which mediate the physical interactions between microtubules and components of the cytoskeleton. Additionally we are shipping Microtubule-Associated Protein 1 Light Chain 3 alpha Antibodies (289) and Microtubule-Associated Protein 1 Light Chain 3 alpha Kits (11) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat MAP1LC3A MAP1LC3A 25291 P14669
MAP1LC3A 84557 Q9H492
MAP1LC3A 66734 Q91VR7
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Top Microtubule-Associated Protein 1 Light Chain 3 alpha Proteins at antibodies-online.com

Showing 8 out of 15 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag 1 mg Log in to see 16 Days
$206.80
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 7 to 8 Days
$407.00
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,236.67
Details
HOST_Escherichia coli (E. coli) Mouse Biotin   1 mg Log in to see 3 to 4 Days
$4,009.50
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 3 to 4 Days
$467.86
Details

MAP1LC3A Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
, , , ,
Mouse (Murine)
,

Top referenced Microtubule-Associated Protein 1 Light Chain 3 alpha Proteins

  1. Human MAP1LC3A Protein expressed in Wheat germ - ABIN1310152 : Martinet, Schrijvers, Timmermans, Bult, De Meyer: Immunohistochemical analysis of macroautophagy: recommendations and limitations. in Autophagy 2013 (PubMed)
    Show all 3 references for ABIN1310152

  2. Human MAP1LC3A Protein expressed in Escherichia coli (E. coli) - ABIN667806 : Mann, Hammarback: Gene localization and developmental expression of light chain 3: a common subunit of microtubule-associated protein 1A(MAP1A) and MAP1B. in Journal of neuroscience research 1997 (PubMed)
    Show all 2 references for ABIN667806

  3. Human MAP1LC3A Protein expressed in Escherichia coli (E. coli) - ABIN2006148 : Schoenfeld, McKerracher, Obar, Vallee: MAP 1A and MAP 1B are structurally related microtubule associated proteins with distinct developmental patterns in the CNS. in The Journal of neuroscience : the official journal of the Society for Neuroscience 1989 (PubMed)

More Proteins for Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A) Interaction Partners

Human Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A) interaction partners

  1. Consistent with the in vitro results, we observed that the expression of autophagy marker LC3 was increased.

  2. Up-regulation of LC3 is associated with carcinogenesis and progression of Salivary Adenoid Cystic Carcinoma.

  3. LC3 is exploited by coxsackievirus in both autophagy-dependent and -independent manners in vivo

  4. Autophagy status, as determined by combined LC3, Beclin 1 and p62 expression, might be independently associated with poor survival in patients with gastric cancer.

  5. Western blot and immunofluorescence validated antibody specificity, knockdown efficiency and autophagy induction prior to fixation in formalin and embedding in paraffin. LC3B and p62 antibodies were validated on cell pellets

  6. FYCO1 (show FYCO1 Proteins) requires a functional LC3A/B-preferring LC3-interacting Region (LIR (show CD300C Proteins)) motif to facilitate efficient maturation of autophagosomes under basal conditions, whereas starvation-induced autophagy was unaffected

  7. In colorectal cancer, differentiation degree and lymph node metastasis were associated with LC3 overexpression. LC3 expression was significantly higher in cancerous tissue than in adjacent tissue.

  8. high nuclear HMGB1 (show HMGB1 Proteins) levels and cytoplasmic HMGB1 (show HMGB1 Proteins) expression predicted poor overall survival (OS) and disease-free survival (DFS (show FST Proteins)). Meanwhile, high LC3 expression was associated with favorable prognosis.

  9. These results demonstrate the essential role of BECN1 (show BECN1 Proteins) in the functional formation of autophagosomes, but not in LC3B (show MAP1LC3B Proteins) lipidation.

  10. The authors show that LC3 is recruited specifically around secreting Shigella flexneri bacteria that are still present in vacuoles formed during entry and cell-to-cell spread.

Mouse (Murine) Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A) interaction partners

  1. LC3 is exploited by coxsackievirus in both autophagy-dependent and -independent manners in vivo

  2. LC3 overexpression thus exerts neuroprotection through increasing alpha7nAChR expression for eAbeta binding and further enhancing autophagic activity for Abeta (show APP Proteins) clearance in vitro and in vivo.

  3. we describe basic protocols to measure the levels of endogenous LC3 and p62 by immunoblotting in cultured mammalian cells

  4. Clusterin (show CLU Proteins) facilitates stress-induced lipidation of LC3 and autophagosome biogenesis to enhance cancer cell survival.

  5. Data indicate that Rubicon (Kiaa0226 (show KIAA0226 Proteins)) and NOX2 (gp91phox (show CYBB Proteins)) are involved in microtubule-associated protein (show SPAG5 Proteins) LC3-associated phagocytosis.

  6. starvation activates the autophagic PI3K, which in turn induces the recruitment of COPII to the endoplasmic reticulum-Golgi intermediate compartment to bud LC3 lipidation-active vesicles as one potential membrane source of the autophagosome.

  7. With increasing age, the expression of LC3 in articular cartilage decreased.

  8. In SOD1 (show SOD1 Proteins) and Neurotomized mice the results of this studysuggest LC3, Fn14 (show TNFRSF12A Proteins), Bcl3 (show BCL3 Proteins) and Gadd45a (show GADD45A Proteins) as candidate genes involved in the maintenance of the severe atrophic state.

  9. Japanese encephalitis virus replication is negatively regulated by autophagy and occurs on LC3-I- and EDEM1 (show EDEM1 Proteins)-containing membranes

  10. Phosphorylation of LC3 by the STK3 (show PKN1 Proteins) and STK4 is essential for autophagy.

Zebrafish Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A) interaction partners

  1. Hedgehog (show SHH Proteins) signaling is required for the Lc3 synthase (show B3GNT5 Proteins) expression in embryonic lens

Pig (Porcine) Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A) interaction partners

  1. LC3 is localized in porcine oocytes during in vitro maturation.

  2. Data suggest that expression of MAP1LC3A in graafian follicle/granulosa cell/theca cell is distinct in normal pigs versus miniature pigs; expression of MAP1LC3A is higher in normal pigs than in miniature pigs; MAP1LC3A may be marker of autophagy.

  3. Data indicate that the expression of MAP1LC3A, B and autophagy-associated genes (ATG5 (show ATG5 Proteins), mTOR (show FRAP1 Proteins), Beclin-1 (show BECN1 Proteins)) was increased in normal pigs, while decreased in miniature pigs.

Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A) Protein Profile

Protein Summary

MAP1A and MAP1B are microtubule-associated proteins which mediate the physical interactions between microtubules and components of the cytoskeleton. MAP1A and MAP1B each consist of a heavy chain subunit and multiple light chain subunits. The protein encoded by this gene is one of the light chain subunits and can associate with either MAP1A or MAP1B. Two transcript variants encoding different isoforms have been found for this gene. The expression of variant 1 is suppressed in many tumor cell lines, suggesting that may be involved in carcinogenesis.

Gene names and symbols associated with MAP1LC3A

  • microtubule-associated protein 1 light chain 3 alpha (map1lc3a)
  • microtubule-associated protein 1 light chain 3 alpha (MAP1LC3A)
  • annexin A3 (Anxa3)
  • microtubule-associated protein 1 light chain 3 alpha (Map1lc3a)
  • microtubule-associated protein 1 light chain 3 beta (map1lc3b)
  • UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5a (b3gnt5a)
  • 1010001H21Rik protein
  • 4922501H04Rik protein
  • Anx3 protein
  • ATG8E protein
  • b3gnt5 protein
  • fb12f12 protein
  • Lc3 protein
  • LC3a protein
  • LRRGT00047 protein
  • MAP1ALC3 protein
  • MAP1BLC3 protein
  • Map1lc3 protein
  • map1lc3a protein
  • MGC69006 protein
  • MGC89867 protein
  • wu:fb12f12 protein
  • wu:fb60g11 protein
  • wu:fe50g08 protein
  • zgc:56434 protein
  • zgc:77094 protein

Protein level used designations for MAP1LC3A

microtubule-associated protein 1 light chain 3 alpha , 35-alpha calcimedin , Annexin III (Lipocortin III) , PAP-III , annexin-3 , lipocortin III , placental anticoagulant protein III , MAP1 light chain 3-like protein 1 , MAP1A/1B light chain 3 A , MAP1A/MAP1B LC3 A , MAP1A/MAP1B light chain 3 A , autophagy-related ubiquitin-like modifier LC3 A , microtubule-associated proteins 1A/1B light chain 3 , microtubule-associated proteins 1A/1B light chain 3A , autophagy-related protein LC3 A , microtubule-associated protein 1-light chain 3A , microtubule-associated proteins 1A/1B light chain 3B , Lc3 , BGnT-5A , UDP-GlcNAc:beta-Gal beta-1,3-N-acetylglucosaminyltransferase 5A , UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 , beta-1,3-Gn-T5A , beta-1,3-N-acetylglucosaminyltransferase 5A , beta-1,3-N-acetylglucosaminyltransferase-5A , beta3Gn-T5A , lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase A , lactotriaosylceramide synthase A , lc(3)Cer synthase A , lc3 synthase A

GENE ID SPECIES
379556 Xenopus laevis
493344 Xenopus (Silurana) tropicalis
744937 Pan troglodytes
100194503 Salmo salar
25291 Rattus norvegicus
84557 Homo sapiens
66734 Mus musculus
362245 Rattus norvegicus
406466 Danio rerio
380234 Xenopus laevis
419142 Gallus gallus
477201 Canis lupus familiaris
100322893 Sus scrofa
514547 Bos taurus
322425 Danio rerio
336526 Danio rerio
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