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The substrate transported is not yet known. Additionally we are shipping MTCH2 Antibodies (50) and MTCH2 Proteins (4) and many more products for this protein.
The BID (show BID ELISA Kits)-MTCH2 axis regulates the differentiation/apoptosis of stem cells and mitochondrial metabolism. (Review)
Data indicate that Mtch2 accelerated conformational change in membrane-bound tBid (Bid (show BID ELISA Kits)) enables it to activate Bax (show BAX ELISA Kits).
Compares and contrasts all the known human SLC25A (show SLC25A25 ELISA Kits)* genes and includes functional information.
Results imply a regulatory role for TMEM18 (show TMM18 ELISA Kits), BDNF (show BDNF ELISA Kits), MTCH2 and NEGR1 (show NEGR1 ELISA Kits) in adipocyte differentiation and biology. In addition, we show a variation of MAF (show MAF ELISA Kits) expression during adipogenesis, while NPC1 (show NPC1 ELISA Kits), PTER (show PTER ELISA Kits) and SH2B1 (show SH2B1 ELISA Kits) were not regulated.
Our study supports earlier reports of SH2B1 (show SH2B1 ELISA Kits) to be of importance in insulin (show INS ELISA Kits) sensitivity and, in addition, suggests potential roles of NEGR1 (show NEGR1 ELISA Kits) and MTCH2.
Molecular basis of the interaction between proapoptotic truncated BID (show BID ELISA Kits) (tBID) protein and mitochondrial carrier (show UCP3 ELISA Kits) homologue 2 (MTCH2) protein
Gene-treatment interactions were observed for short-term weight loss. (MTCH2 rs10838738, Plifestyle*SNP = 0.022)
MTCH2 may play a role in cellular processes underlying obesity
MTCH2 rs 10838738 is associated with higher body mass index.
Mtch2 is a mitochondrial target of tBID and possibly participates in the mitochondrial apoptotic program.
Loss of MTCH2 increases muscle metabolism, energy expenditure, heart function, and protects from diet-induced obesity.
Loss of Mtch2 increases mitochondrial OXPHOS, triggering HSC (show FUT1 ELISA Kits) entry into cycle. Elevated OXPHOS is accompanied by an increase in mitochondrial size, increase in ATP and ROS (show ROS1 ELISA Kits) levels, and protection from irradiation-induced apoptosis.
The substrate transported is not yet known. Induces mitochondrial depolarization (By similarity).
, met-induced mitochondrial protein
, mitochondrial carrier homolog 2
, solute carrier family 25, member 50