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Mitochondrial Fission Factor Proteins (MFF)

This is a nuclear gene encoding a protein that functions in mitochondrial and peroxisomal fission. Additionally we are shipping Mitochondrial Fission Factor Antibodies (46) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
MFF 56947 Q9GZY8
MFF 75734 Q6PCP5
MFF 301563 Q4KM98
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Top Mitochondrial Fission Factor Proteins at antibodies-online.com

Showing 7 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Yeast Pongo abelii His tag   1 mg Log in to see 56 to 66 Days
$2,480.50
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,480.50
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,480.50
Details

MFF Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine) ,
,
Rat (Rattus)

More Proteins for Mitochondrial Fission Factor (MFF) Interaction Partners

Human Mitochondrial Fission Factor (MFF) interaction partners

  1. membrane-anchored Mff differentially regulates various Drp1 isoforms.

  2. Data show that expression of MFF protein, miR-593-5p and BRCA1 protein correlates with cisplatin sensitivity and survival of tongue squamous cell carcinoma (TSCC).

  3. loss of Mff results in failure of Parkin (show PARK2 Proteins) translocation and final clearance of damaged mitochondria

  4. Mitochondrial fission factor (MFF) mRNA is a direct target of miR (show MLXIP Proteins)-27, whose ectopic expression decreases MFF expression through binding to its 3'-untranslated region.

  5. MiD49 and MiD51 can act independently of Mff and Fis1 in Drp1 recruitment and suggest that they provide specificity to the division of mitochondria.

  6. TRAP1 (show TRAP1 Proteins) controls mitochondrial fusion/fission balance through Drp1 (show CRMP1 Proteins) and Mff expression.

  7. PEX11 proteins attract both Mff and human Fis1 (hFis1 (show FIS1 Proteins)) to their site of action.

  8. MFF over-expression results in extensive mitochondrial fragmentation, driving mitochondrial dysfunction. MFF fibroblasts undergo oxidative stress, with increased ROS (show ROS1 Proteins) production, and the onset of autophagy and mitophagy.

  9. MFF gene expression is decreased in both classic and follicular variants of papillary thyroid carcinoma.

  10. Mff is a novel component of a conserved membrane fission pathway used for constitutive and induced fission of mitochondria and peroxisomes.

Mouse (Murine) Mitochondrial Fission Factor (MFF) interaction partners

  1. Mff cannot bind to assembly-deficient mutants of Drp1, suggesting that Mff selectively interacts with higher-order complexes of Drp1.

  2. membrane-anchored Mff differentially regulates various Drp1 isoforms.

  3. These findings provide a mechanism wherein the multimeric states of both Mff and Drp1 regulate their collaborative interaction.

  4. Ablating Mfn1 (show MFN1 Proteins) eliminates the cardiac-related lethality of Mff knockout mice.

  5. Mitochondrial fission factor has been identified as a new AMPK (show PRKAA1 Proteins) substrate.

  6. This study reveals a novel model of mitochondrial fission regulation, which is composed of miR (show MLXIP Proteins)-761 and mitochondrial fission factor

  7. MiD49 and MiD51 can act independently of Mff and Fis1 in Drp1 recruitment and suggest that they provide specificity to the division of mitochondria.

  8. immunofluorescence analysis of Drp1 suggests that Fis1 and Mff are important for the number and size of Drp1 puncta on mitochondria.

Mitochondrial Fission Factor (MFF) Protein Profile

Protein Summary

This is a nuclear gene encoding a protein that functions in mitochondrial and peroxisomal fission. The encoded protein recruits dynamin-1-like protein (DNM1L) to mitochondria. There are multiple pseudogenes for this gene on chromosomes 1, 5, and X. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with MFF

  • mitochondrial fission factor (mff)
  • mitochondrial fission factor (mff-b)
  • mitochondrial fission factor (mff-a)
  • mitochondrial fission factor (MFF)
  • mitochondrial fission factor (Mff)
  • 5230400G24Rik protein
  • AI314724 protein
  • C2H2orf33 protein
  • C2orf33 protein
  • GL004 protein
  • mff protein
  • MGC79121 protein
  • MGC80099 protein
  • RGD1310230 protein
  • zgc:66022 protein

Protein level used designations for MFF

mitochondrial fission factor homolog B , mitochondrial fission factor homolog A , mitochondrial fission factor , Uncharacterized protein C2orf33 homolog

GENE ID SPECIES
393508 Danio rerio
443869 Xenopus laevis
446760 Xenopus laevis
459989 Pan troglodytes
708489 Macaca mulatta
100056853 Equus caballus
100328889 Oryctolagus cuniculus
100379850 Xenopus (Silurana) tropicalis
100414285 Callithrix jacchus
100579991 Nomascus leucogenys
424796 Gallus gallus
56947 Homo sapiens
506291 Bos taurus
75734 Mus musculus
301563 Rattus norvegicus
100513442 Sus scrofa
100173373 Pongo abelii
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