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Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Additionally we are shipping Mitochondrially Encoded NADH Dehydrogenase 5 Kits (10) and Mitochondrially Encoded NADH Dehydrogenase 5 Proteins (4) and many more products for this protein.
Showing 10 out of 57 products:
Human Polyclonal MT-ND5 Primary Antibody for ELISA, WB - ABIN1535072
Anderson, Bankier, Barrell, de Bruijn, Coulson, Drouin, Eperon, Nierlich, Roe, Sanger, Schreier, Smith, Staden, Young: Sequence and organization of the human mitochondrial genome. in Nature 1981
Human Polyclonal MT-ND5 Primary Antibody for IF (p), IHC (p) - ABIN751633
Wu, Zhang, Nickerson, Gao, Sun, Chen, Zhang, Zhang, Gao, Chen, Luo, Wang, Sun: Cumulative mtDNA damage and mutations contribute to the progressive loss of RGCs in a rat model of glaucoma. in Neurobiology of disease 2015
Mitochondrially encoded NADH dehydrogenase (show NDUFA1 Antibodies) subunit, complex I extracts energy from NADH, produced by the oxidation of sugars and fats (show C10ORF90 Antibodies), and traps the energy in a potential difference or voltage across the mitochondrial inner membrane.
Study demonstrates a link between p53 (show TP53 Antibodies) and Bcl-2 (show BCL2 Antibodies) proteins as regulators of ROS (show ROS1 Antibodies) production and cellular invasiveness, and reveals complex-I, especially ND5, as their functional target in lung tumor cells.
Three mutations were significantly related to the presence of epilepsy. These mutations were found at the 8502, 11994, and 13,231 bp of mtDNA, which resulted in amino acid changes at the MT-ATP-8, MT-ND4 (show MT-ND4 Antibodies) and MT-ND5 genes.
Point mutations m.10191T>C in mitochondrial ND3 (show MT-ND3 Antibodies) gene, m.13513G>A in ND5 gene and m.14,453G>A in ND6 (show MT-ND6 Antibodies) gene were detected in three Chinese children with Leigh synrome dur to complex I deficiency.
Mitochondrial ND5 12338T>C variant is associated with maternally inherited hypertrophic cardiomyopathy in a Chinese pedigree
Mitochondrial DNA mutations in respiratory complex-I in never-smoker lung cancer patients contribute to lung cancer progression in association with EGFR (show EGFR Antibodies) gene mutation.
ND4 (show MT-ND4 Antibodies) G11696A and ND5 T12338C mutation is likely associated with Leber's hereditary optic neuropathy in two Chinese families
Patients with ND5*13513 G to A mutation may have a characteristic clinical course and ND5 *13513 G to A might be a preferential candidate mutation of Leigh syndrome.
these results suggest that the MT-ND1 (show MT-ND1 Antibodies) and MT-ND5 genes are mutational hotspots for Chinese families with suspected LHON lacking the common primary mutations.
One proband had a non-synonymous A14062G mutation in the ND5 gene.
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
NADH dehydrogenase subunit 5