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The protein encoded by MAP3K10 is a member of the serine/threonine kinase family. Additionally we are shipping MAP3K10 Antibodies (62) and many more products for this protein.
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MAP3K4 (show MAP3K4 Proteins) is sufficiently mediate the TGFbeta (show TGFB1 Proteins)-induced phosphorylation of p38 MAPK (show MAPK14 Proteins) in MEFs and HaCaT cells.
A novel and important role for MAP3K10 in the proliferation and chemoresistance of pancreatic ductal adenocarcinoma.
This study showed that show that RUNX3 (show RUNX3 Proteins) is a principal and evolutionarily conserved component of the MST pathway.
Mechanism of MAP kinase (show MAPK1 Proteins) activation by TNF (show TNF Proteins) requires Src (show SRC Proteins)-dependent activation of Vav (show VAV1 Proteins), activation of Rac (show AKT1 Proteins)/Cdc42 (show CDC42 Proteins), and the engagement of the Rac (show AKT1 Proteins)/Cdc42 (show CDC42 Proteins) interaction site on MLK2 and 3.
Data show that miR (show MLXIP Proteins)-181b contributed to proliferation of AML (show RUNX1 Proteins) cells by targeting MLK2.
MLK2 has a role in vesicle formation and endosome recycling by binding to clathrin
demonstrate Alien-MLK2 interaction and also show that MLK2 is able to phosphorylate Alien; Alien, DAX-1 (show NR0B1 Proteins) and thyroid hormone receptor (show THRA Proteins) mediated transcriptional silencing is strongly enhanced in the presence of active MLK2
MLK2 and -3 are required for activation of JNK (show MAPK8 Proteins) and p38 (show CRK Proteins) by ectopically expressed GCK (show GCK Proteins)
Hippocalcin (show HPCA Proteins) and MLK2 were colocalized in the halo of Lewy bodies in Parkinson disease patients, and neither protein was detected in normal pigmented neurons.
Mixed lineage kinase (show MAP3K12 Proteins) phosphorylates transcription factor E47 (show TCF3 Proteins) and inhibits TrkB (show NTRK2 Proteins) expression to link neuronal death and survival pathways
There is extensive functional redundancy between MLK1 (show MAP3K9 Proteins) and MLK2, and the other member of the family, MLK3, none of which are required for survival in mouse.
The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase has been shown to activate MAPK8/JNK and MKK4/SEK1, and this kinase itself can be phoshorylated, and thus activated by JNK kinases. This kinase functions preferentially on the JNK signaling pathway, and is reported to be involved in nerve growth factor (NGF) induced neuronal apoptosis.
mitogen-activated protein kinase kinase kinase 10
, mixed-lineage kinase 2
, MKN28 derived nonreceptor_type serine/threonine kinase
, MKN28 kinase
, mixed lineage kinase 2
, protein kinase MST
, MKN28 derived nonreceptor_type
, serine/threonine kinase