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The protein encoded by MAP3K10 is a member of the serine/threonine kinase family. Additionally we are shipping MAP3K10 Proteins (7) and many more products for this protein.
Showing 10 out of 66 products:
Human Polyclonal MAP3K10 Primary Antibody for IHC (p), WB - ABIN392424
Humphrey, Newcomb, Yu, Hao, Yu, Krajewski, Du, Jhala: Mixed lineage kinase-3 stabilizes and functionally cooperates with TRIBBLES-3 to compromise mitochondrial integrity in cytokine-induced death of pancreatic beta cells. in The Journal of biological chemistry 2010
Show all 5 Pubmed References
We identified a direct target of miR (show MLXIP Antibodies)-155 as MAP3K10 in osteosarcoma
MAP3K4 (show MAP3K4 Antibodies) is sufficiently mediate the TGFbeta (show TGFB1 Antibodies)-induced phosphorylation of p38 MAPK (show MAPK14 Antibodies) in MEFs and HaCaT cells.
A novel and important role for MAP3K10 in the proliferation and chemoresistance of pancreatic ductal adenocarcinoma.
This study showed that show that RUNX3 (show RUNX3 Antibodies) is a principal and evolutionarily conserved component of the MST pathway.
Mechanism of MAP kinase (show MAPK1 Antibodies) activation by TNF (show TNF Antibodies) requires Src (show SRC Antibodies)-dependent activation of Vav (show VAV1 Antibodies), activation of Rac (show AKT1 Antibodies)/Cdc42 (show CDC42 Antibodies), and the engagement of the Rac (show AKT1 Antibodies)/Cdc42 (show CDC42 Antibodies) interaction site on MLK2 and 3.
Data show that miR (show MLXIP Antibodies)-181b contributed to proliferation of AML (show RUNX1 Antibodies) cells by targeting MLK2.
MLK2 has a role in vesicle formation and endosome recycling by binding to clathrin
demonstrate Alien-MLK2 interaction and also show that MLK2 is able to phosphorylate Alien; Alien, DAX-1 (show NR0B1 Antibodies) and thyroid hormone receptor (show THRA Antibodies) mediated transcriptional silencing is strongly enhanced in the presence of active MLK2
MLK2 and -3 are required for activation of JNK (show MAPK8 Antibodies) and p38 (show CRK Antibodies) by ectopically expressed GCK (show GCK Antibodies)
Hippocalcin (show HPCA Antibodies) and MLK2 were colocalized in the halo of Lewy bodies in Parkinson disease patients, and neither protein was detected in normal pigmented neurons.
There is extensive functional redundancy between MLK1 (show MAP3K9 Antibodies) and MLK2, and the other member of the family, MLK3 (show KCNK7 Antibodies), none of which are required for survival in mouse.
Mixed lineage kinase (show MAP3K12 Antibodies) phosphorylates transcription factor E47 (show TCF3 Antibodies) and inhibits TrkB (show NTRK2 Antibodies) expression to link neuronal death and survival pathways
The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase has been shown to activate MAPK8/JNK and MKK4/SEK1, and this kinase itself can be phoshorylated, and thus activated by JNK kinases. This kinase functions preferentially on the JNK signaling pathway, and is reported to be involved in nerve growth factor (NGF) induced neuronal apoptosis.
mitogen-activated protein kinase kinase kinase 10
, mixed-lineage kinase 2
, MKN28 derived nonreceptor_type serine/threonine kinase
, MKN28 kinase
, mixed lineage kinase 2
, protein kinase MST
, MKN28 derived nonreceptor_type
, serine/threonine kinase