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Mitogen-Activated Protein Kinase Kinase Kinase 9 Proteins (MAP3K9)

Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. Additionally we are shipping MAP3K9 Antibodies (73) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
MAP3K9 4293 P80192
MAP3K9 338372 Q3U1V8
Rat MAP3K9 MAP3K9 500690  
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Top MAP3K9 Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Baculovirus infected Insect Cells Human GST tag   5 μg Log in to see 10 to 12 Days
$322.08
Details

MAP3K9 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

More Proteins for Mitogen-Activated Protein Kinase Kinase Kinase 9 (MAP3K9) Interaction Partners

Human Mitogen-Activated Protein Kinase Kinase Kinase 9 (MAP3K9) interaction partners

  1. miR148b directly targeted mitogenactivated protein kinase (show CDK7 Proteins) (MAPK (show MAPK1 Proteins)) kinase kinase 9 (MAP3K9), an upstream activator of MAPK (show MAPK1 Proteins) kinase/cJun (show JUN Proteins) Nterminal kinase (JNK (show MAPK8 Proteins)) signaling, suppressing the protein but not the mRNA levels.

  2. identified three kinases with gain-of-function mutations in lung cancer, namely FGFR4 (show FGFR4 Proteins), MAP3K9, and PAK5 (show PAK6 Proteins). Mutations in these kinases are activating toward the ERK (show EPHB2 Proteins) pathway, and targeted depletion of the mutated kinases inhibits proliferation

  3. It was found that 24% of melanoma cell lines have mutations in the protein-coding regions of either MAP3K5 (show MAP3K5 Proteins) or MAP3K9.

  4. estrogen receptor-alpha (show ESR1 Proteins) transcriptional activity is repressed by the Rho/megakaryoblastic leukemia 1 signaling pathway

Mouse (Murine) Mitogen-Activated Protein Kinase Kinase Kinase 9 (MAP3K9) interaction partners

  1. These results show that the expression of nucleosomal SRF-dependent genes, including the SMC gene, is activated by MKL1 via activation of SRF and recruitment of the FACT complex.

  2. There is extensive functional redundancy between MLK1 and MLK2 (show MAP3K10 Proteins), and the other member of the family, MLK3, none of which are required for survival in mouse.

MAP3K9 Protein Profile

Protein Summary

Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. Plays an important role in the cascades of cellular responses evoked by changes in the environment. Once activated, acts as an upstream activator of the MKK/JNK signal transduction cascade through the phosphorylation of MAP2K4/MKK4 and MAP2K7/MKK7 which in turn activate the JNKs. The MKK/JNK signaling pathway regulates stress response via activator protein-1 (JUN) and GATA4 transcription factors. Plays also a role in mitochondrial death signaling pathway, including the release cytochrome c, leading to apoptosis.

Gene names and symbols associated with MAP3K9

  • mitogen-activated protein kinase kinase kinase 9 (MAP3K9)
  • mitogen-activated protein kinase kinase kinase 9 (Map3k9)
  • E130314H24Rik protein
  • MEKK9 protein
  • Mlk1 protein
  • Prke1 protein
  • RGD1562149 protein

Protein level used designations for MAP3K9

mixed lineage kinase 1 (tyr and ser/thr specificity) , mitogen activated protein kinase kinase kinase 9 , mixed-lineage kinase 1

GENE ID SPECIES
4293 Homo sapiens
338372 Mus musculus
500690 Rattus norvegicus
100155753 Sus scrofa
538340 Bos taurus
490765 Canis lupus familiaris
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