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Mitogen-Activated Protein Kinase Kinase Kinase Kinase 5 Proteins (MAP4K5)

MAP4K5 encodes a member of the serine/threonine protein kinase family, that is highly similar to yeast SPS1/STE20 kinase. Additionally we are shipping Mitogen-Activated Protein Kinase Kinase Kinase Kinase 5 Antibodies (48) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
MAP4K5 11183 Q9Y4K4
MAP4K5 399510 Q8BPM2
Rat MAP4K5 MAP4K5 503027  
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Top Mitogen-Activated Protein Kinase Kinase Kinase Kinase 5 Proteins at antibodies-online.com

Showing 10 out of 11 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Baculovirus infected Insect Cells Human His tag,GST tag 50 μg Log in to see 16 Days
$338.80
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$739.20
Details
HOST_Escherichia coli (E. coli) Mouse His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$756.80
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details
HOST_Baculovirus infected Insect Cells Human GST tag   5 μg Log in to see 10 to 12 Days
$322.08
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 9 to 19 Days
$920.54
Details
HOST_Escherichia coli (E. coli) Mouse Un-conjugated   100 μg Log in to see 9 to 19 Days
$936.27
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

MAP4K5 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, , ,
Mouse (Murine)
,

Top referenced Mitogen-Activated Protein Kinase Kinase Kinase Kinase 5 Proteins

  1. Human MAP4K5 Protein expressed in Baculovirus infected Insect Cells - ABIN2004770 : Tung, Blenis: A novel human SPS1/STE20 homologue, KHS, activates Jun N-terminal kinase. in Oncogene 1997 (PubMed)

More Proteins for Mitogen-Activated Protein Kinase Kinase Kinase Kinase 5 (MAP4K5) Interaction Partners

Human Mitogen-Activated Protein Kinase Kinase Kinase Kinase 5 (MAP4K5) interaction partners

  1. MAP4K5 expression is decreased or lost in majority of pancreatic ductal adenocarcinoma.

  2. TNF (show TNF Proteins) signaling leads to oligomerization, ubiquitination, and activation of GCKR (show GCKR Proteins) and activation of the SAPK (show MAPK9 Proteins) pathway in a manner that depends upon TRAF2 (show TRAF2 Proteins) polyubiquitination and oligomerization and Ubc13 (show UBE2N Proteins) function

  3. The -822G/A polymorphism in the promoter region of the MAP4K5 gene is associated with reduced risk of type 2 diabetes in Han Chinese from Shanghai.

Mouse (Murine) Mitogen-Activated Protein Kinase Kinase Kinase Kinase 5 (MAP4K5) interaction partners

  1. Germinal center kinase-related enzyme (GCKR (show GCKR Proteins)) facilitates both canonical and noncanonical Wnt (show WNT2 Proteins) signaling in B lymphocytes.

Mitogen-Activated Protein Kinase Kinase Kinase Kinase 5 (MAP4K5) Protein Profile

Protein Summary

This gene encodes a member of the serine/threonine protein kinase family, that is highly similar to yeast SPS1/STE20 kinase. Yeast SPS1/STE20 functions near the beginning of the MAP kinase signal cascades that is essential for yeast pheromone response. This kinase was shown to activate Jun kinase in mammalian cells, which suggested a role in stress response. Two alternatively spliced transcript variants encoding the same protein have been described for this gene.

Gene names and symbols associated with MAP4K5

  • mitogen-activated protein kinase kinase kinase kinase 5 (MAP4K5)
  • mitogen-activated protein kinase kinase kinase kinase 5 (Map4k5)
  • mitogen-activated protein kinase kinase kinase kinase 5 (map4k5)
  • 4432415E19Rik protein
  • fl74c10 protein
  • GCKR protein
  • KHS protein
  • KHS1 protein
  • MAPKKKK5 protein
  • RGD1562028 protein
  • wu:fl74c10 protein
  • zgc:55719 protein
  • zgc:55985 protein

Protein level used designations for MAP4K5

MAPK/ERK kinase kinase kinase 5 , MEK kinase kinase 5 , MEKKK 5 , germinal center kinase-related , kinase homologous to SPS1/STE20

GENE ID SPECIES
11183 Homo sapiens
399510 Mus musculus
503027 Rattus norvegicus
334565 Danio rerio
447339 Xenopus laevis
490685 Canis lupus familiaris
781335 Bos taurus
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