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Activates the JUN N-terminal pathway (By similarity).. Additionally we are shipping Mitogen-Activated Protein Kinase Kinase Kinase MLK4 Proteins (5) and many more products for this protein.
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Human Polyclonal KIAA1804 Primary Antibody for IP, WB - ABIN445417
Guo, Miyoshi, Dubner, Gu, Li, Liu, Yang, Zou, Ren, Noguchi, Wei: Spinal 5-HT3 receptors mediate descending facilitation and contribute to behavioral hypersensitivity via a reciprocal neuron-glial signaling cascade. in Molecular pain 2014
results uncover MLK4 as an upstream regulator of NF-kappaB (show NFKB1 Antibodies) signaling and a potential molecular target for the MES (show ME1 Antibodies) subtype of glioblastomas
In establishing the role of MLK4 in intracellular signaling, we show it directly phosphorylates MEK1 (MAP2K1 (show MAP2K1 Antibodies)) and that MEK (show MAP2K1 Antibodies)/ERK (MAPK1 (show MAPK1 Antibodies)) signaling is impaired in MLK4 knockout cells
MLK4 is a negative regulator of TLR4 (show TLR4 Antibodies) signaling.
Activates the JUN N-terminal pathway (By similarity).
mitogen-activated protein kinase kinase kinase MLK4
, mixed lineage kinase 4
, mixed lineage kinase 4-like