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Mix Paired-Like Homeobox Proteins (MIXL1)

Homeodomain proteins, such as MIXL1, are transcription factors that regulate cell fate during development (Hart et al., 2005 [PubMed 15982639]).[supplied by OMIM, Mar 2008].. Additionally we are shipping MIXL1 Antibodies (40) and and many more products for this protein.

list all proteins Gene Name GeneID UniProt
MIXL1 83881 Q9H2W2
Rat MIXL1 MIXL1 289311  
MIXL1 27217 Q9WUI0
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Top MIXL1 Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Chicken His tag   1 mg Log in to see 56 to 66 Days
$2,517.17
Details

MIXL1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for Mix Paired-Like Homeobox (MIXL1) Interaction Partners

Human Mix Paired-Like Homeobox (MIXL1) interaction partners

  1. Findings support the existence of a novel MIXL1-c REL (show NFkBP65 Proteins) mediated survival axis in AML (show RUNX1 Proteins) that can be targeted by BMPR1 (show BMPR1A Proteins) inhibitors. (MIXL1- human gene, Mixl1- mouse ortholog, MIXL1- protein).

  2. results demonstrate that Mixl1 and Flk1 play roles...during dimethyl sulfoxide-induced mesodermal specification in P19 cells.

  3. Brachyury (show TBX1 Proteins) and related Tbx proteins interact with the Mixl1 homeodomain protein and negatively regulate Mixl1 transcriptional activity

  4. These results demonstrate for a functional role for TGF-beta (show TGFB1 Proteins) ligands in regulation of mammalian Mixl1, identify FoxH1 (show FOXH1 Proteins) as an essential co-activator, and implicate Nodal as the embryonic regulator of Mixl1 in mesendoderm morphogenesis.

  5. MIXL1 protein is differentially expressed in non-Hodgkin lymphoma and Hodgkin lymphoma; findings suggest that MIXL1 overexpression may play a role in driving proliferatin or blocking differentiation in lymphoma oncogenesis

  6. Targeted insertion in human embryonic stem cells of sequences encoding green fluorescent protein (GFP) into the locus of MIXL1, a gene transiently expressed in the primitive streak during embryogenesis.

Mouse (Murine) Mix Paired-Like Homeobox (MIXL1) interaction partners

  1. In this study, we demonstrated that forced expression of Mix-like protein 1 (encoded by Mixl1) can be used to guide contribution of mouse embryonic stem cells to endodermal organs after blastocyst injection.

  2. Embryonic localization of Mixl1 shows its co-localized with the early hematopoietic marker, Runx1 (show RUNX1 Proteins), in the allantois and visceral yolk sac (show ADCY10 Proteins) blood islands.

  3. At later stages, in contrast with wild-type embryos, E7.5-8.0, Mixl1 knockout (KO) KO/KO (show KRT8 Proteins) embryos lacked morphologically recognizable midline structures such as the node and notochord.

  4. Brachyury (show TBX1 Proteins) and related Tbx proteins interact with the Mixl1 homeodomain protein and negatively regulate Mixl1 transcriptional activity

  5. These data support the hypothesis that Mixl1 directly regulates Pdgfralpha and Flk1 (show KDR Proteins) gene expression.

  6. results strongly suggest that Gsc (show GSC Proteins) is a direct target gene of Mixl1 during embryogenesis.

  7. required for the morphogenesis of axial mesoderm, the heart and the gut (show GUSB Proteins) during embryogenesis

  8. Mixl1 is required for efficient haematopoiesis and BMP4 (show BMP4 Proteins)-induced ventral mesoderm patterning in differentiating ES cells

  9. all mice reconstituted with Mixl1-transduced bone marrow developed fatal, transplantable acute myeloid leukemia (show BCL11A Proteins) with a mean latency period of 200 days

  10. As goosecoid (show GSC Proteins) is itself induced in a Foxh1 (show FOXH1 Proteins)-dependent manner, we propose that Foxh1 (show FOXH1 Proteins) initiates positive and negative transcriptional circuits to refine cell fate decisions during gastrulation

MIXL1 Protein Profile

Protein Summary

Homeodomain proteins, such as MIXL1, are transcription factors that regulate cell fate during development (Hart et al., 2005

Gene names and symbols associated with MIXL1

  • Mix1 homeobox-like 1 (Xenopus laevis) (MIXL1)
  • Mix-like homeobox protein 1 (LOC100347077)
  • Mix paired-like homeobox (MIXL1)
  • Mix paired-like homeobox 1 (Mixl1)
  • Mix1 homeobox-like 1 (Xenopus laevis) (Mixl1)
  • CMIX protein
  • MILD1 protein
  • MIX protein
  • MIXL protein
  • MIXL1 protein
  • Mm1 protein
  • Mml protein

Protein level used designations for MIXL1

Mix1 homeobox-like 1 (Xenopus laevis) , Mix-like homeobox protein 1 , MIX1 homeobox-like protein 1 , hMix , homeobox protein MIXL1 , homeodomain protein MIX , mix.1 homeobox-like protein , CMIX homeobox , Mix1 homeobox-like 1 , mMix

GENE ID SPECIES
737620 Pan troglodytes
100347077 Oryctolagus cuniculus
83881 Homo sapiens
395838 Gallus gallus
614854 Bos taurus
289311 Rattus norvegicus
27217 Mus musculus
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