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Homeodomain proteins, such as MIXL1, are transcription factors that regulate cell fate during development (Hart et al., 2005 [PubMed 15982639]).[supplied by OMIM, Mar 2008].. Additionally we are shipping MIXL1 Proteins (4) and and many more products for this protein.
Showing 10 out of 43 products:
Human Polyclonal MIXL1 Primary Antibody for WB - ABIN2779264
Hart, Willson, Wong, Parker, Robb: Transcriptional regulation of the homeobox gene Mixl1 by TGF-beta and FoxH1. in Biochemical and biophysical research communications 2005
Findings support the existence of a novel MIXL1-c REL (show NFkBP65 Antibodies) mediated survival axis in AML (show RUNX1 Antibodies) that can be targeted by BMPR1 (show BMPR1A Antibodies) inhibitors. (MIXL1- human gene, Mixl1- mouse ortholog, MIXL1- protein).
results demonstrate that Mixl1 and Flk1 (show KDR Antibodies) play roles...during dimethyl sulfoxide-induced mesodermal specification in P19 (show CDKN2D Antibodies) cells.
Brachyury (show TBX1 Antibodies) and related Tbx proteins interact with the Mixl1 homeodomain protein and negatively regulate Mixl1 transcriptional activity
These results demonstrate for a functional role for TGF-beta (show TGFB1 Antibodies) ligands in regulation of mammalian Mixl1, identify FoxH1 (show FOXH1 Antibodies) as an essential co-activator, and implicate Nodal as the embryonic regulator of Mixl1 in mesendoderm morphogenesis.
MIXL1 protein is differentially expressed in non-Hodgkin lymphoma and Hodgkin lymphoma; findings suggest that MIXL1 overexpression may play a role in driving proliferatin or blocking differentiation in lymphoma oncogenesis
Targeted insertion in human embryonic stem cells of sequences encoding green fluorescent protein (GFP) into the locus of MIXL1, a gene transiently expressed in the primitive streak during embryogenesis.
In this study, we demonstrated that forced expression of Mix-like protein 1 (encoded by Mixl1) can be used to guide contribution of mouse embryonic stem cells to endodermal organs after blastocyst injection.
Embryonic localization of Mixl1 shows its co-localized with the early hematopoietic marker, Runx1 (show RUNX1 Antibodies), in the allantois and visceral yolk sac (show ADCY10 Antibodies) blood islands.
At later stages, in contrast with wild-type embryos, E7.5-8.0, Mixl1 knockout (KO) KO/KO (show KRT8 Antibodies) embryos lacked morphologically recognizable midline structures such as the node and notochord.
These data support the hypothesis that Mixl1 directly regulates Pdgfralpha and Flk1 (show KDR Antibodies) gene expression.
results strongly suggest that Gsc (show GSC Antibodies) is a direct target gene of Mixl1 during embryogenesis.
required for the morphogenesis of axial mesoderm, the heart and the gut (show GUSB Antibodies) during embryogenesis
Mixl1 is required for efficient haematopoiesis and BMP4 (show BMP4 Antibodies)-induced ventral mesoderm patterning in differentiating ES cells
all mice reconstituted with Mixl1-transduced bone marrow developed fatal, transplantable acute myeloid leukemia (show BCL11A Antibodies) with a mean latency period of 200 days
As goosecoid (show GSC Antibodies) is itself induced in a Foxh1 (show FOXH1 Antibodies)-dependent manner, we propose that Foxh1 (show FOXH1 Antibodies) initiates positive and negative transcriptional circuits to refine cell fate decisions during gastrulation
Homeodomain proteins, such as MIXL1, are transcription factors that regulate cell fate during development (Hart et al., 2005
Mix1 homeobox-like 1 (Xenopus laevis)
, Mix-like homeobox protein 1
, MIX1 homeobox-like protein 1
, homeobox protein MIXL1
, homeodomain protein MIX
, mix.1 homeobox-like protein
, CMIX homeobox
, Mix1 homeobox-like 1