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Mohawk Homeobox Proteins (MKX)

The protein encoded by MKX is an IRX family-related homeobox protein that may play a role in cell adhesion. Additionally we are shipping MKX Antibodies (48) and MKX Kits (2) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
MKX 283078 Q8IYA7
MKX 210719 Q8BIA3
Rat MKX MKX 291228  
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Top MKX Proteins at antibodies-online.com

Showing 5 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Pongo abelii His tag   1 mg Log in to see 56 to 66 Days
$2,959.00
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 9 to 11 Days
$229.85
Details

MKX Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for Mohawk Homeobox (MKX) Interaction Partners

Zebrafish Mohawk Homeobox (MKX) interaction partners

  1. Irxl1/Mkx can repress myoD (show MYOD1 Proteins) expression through direct binding to its promoter and may thus play a negative regulatory role in muscle differentiation.

  2. observations suggest that irxl1 may regulate factors involved in brain and pharyngeal arch development

Human Mohawk Homeobox (MKX) interaction partners

  1. these data shed light on previously unrecognized roles of Mkx in tendinopathy, tenogenesis, and tendon repair as well as in regulating the TGFbeta (show TGFB1 Proteins) pathway.

  2. Reduced expression of MKX is a feature of degenerated anterior cruciate ligament in osteoarthritis-affected joints.

  3. In silico characterization of the C10orf48 sequence

Mouse (Murine) Mohawk Homeobox (MKX) interaction partners

  1. Gtf2ird1 (show GTF2IRD1 Proteins) is essential for Mkx transcription, while also linking mechanical forces to Mkx-mediated tendon homeostasis and regeneration.

  2. these data shed light on previously unrecognized roles of Mkx in tendinopathy, tenogenesis, and tendon repair as well as in regulating the TGFbeta (show TGFB1 Proteins) pathway.

  3. Mkx is an important regulator of the differentiation of VPs and pulleys, as well as of tendon differentiation.

  4. Smad3 binds Scleraxis and Mohawk and regulates tendon matrix organization.

  5. these data identify the unique DNA-recognition properties of MKX and reveal a novel role for Mkx in promoting slow fiber type specification during skeletal muscle differentiation.

  6. These results suggest that Irxl1 is required for the tendon differentiation but dispensable for the patterning of the musculoskeletal system in development.

  7. Mkx mRNA was strongly expressed in differentiating tendon cells during embryogenesis and in the tendon sheath cells in postnatal stages. In addition to defects in tendon collagen fibrillogenesis, Mkx(-/-) mice exhibited abnormal tendon sheaths.

  8. observed small collagen fibril diameters and a down-regulation of type I collagen in Mkx(-/-) tendons.

  9. The developmental expression pattern indicates that Irxl1 is a good candidate gene for the Twirler gene.

  10. Irxl1 is a newly identified highly divergent member of the Irx gene family with specific expression patterns in embryogenesis.

MKX Protein Profile

Protein Summary

The protein encoded by this gene is an IRX family-related homeobox protein that may play a role in cell adhesion. Studies in mice suggest that this protein may be a regulator of tendon development. Two transcript variants encoding the same protein have been found for this gene.

Gene names and symbols associated with Mohawk Homeobox Proteins (MKX)

  • mohawk homeobox (MKX)
  • mohawk homeobox a (mkxa)
  • mohawk homeobox (LOC100357336)
  • mohawk homeobox (mkx)
  • mohawk homeobox (Mkx)
  • 9430023B20Rik protein
  • C10orf48 protein
  • IFRX protein
  • Irxl1 protein
  • irxl1b protein
  • MKX protein
  • mwk protein
  • RGD1305652 protein

Protein level used designations for Mohawk Homeobox Proteins (MKX)

mohawk homeobox , homeobox protein Mohawk , homeobox protein mohawk A , iroquois homeobox-like protein 1b , irxl1 , homeobox protein Mohawk-like , Iroquois family related homeodomain protein , iroquois homeobox protein-like 1

GENE ID SPECIES
450373 Pan troglodytes
799136 Danio rerio
100357336 Oryctolagus cuniculus
100399932 Callithrix jacchus
100604340 Nomascus leucogenys
446664 Xenopus laevis
771284 Gallus gallus
283078 Homo sapiens
487079 Canis lupus familiaris
521239 Bos taurus
210719 Mus musculus
291228 Rattus norvegicus
100173493 Pongo abelii
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