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anti-Monoglyceride Lipase (MGLL) Antibodies

MGLL encodes a serine hydrolase of the AB hydrolase superfamily that catalyzes the conversion of monoacylglycerides to free fatty acids and glycerol. Additionally we are shipping MGLL Proteins (14) and MGLL Kits (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
MGLL 11343 Q99685
MGLL 23945 O35678
MGLL 29254 Q8R431
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Top anti-MGLL Antibodies at antibodies-online.com

Showing 10 out of 133 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Goat Un-conjugated ELISA, WB ABIN334436 (0.5µg/ml) staining of Human Adipose lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 4 to 5 Days
$326.89
Details
Dog Goat Un-conjugated WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Goat Un-conjugated ELISA, WB Western Blot: Monoglyceride Lipase Antibody [ABIN4091190] - HEK293 overexpressing MGLL and probed with (mock transfection in first lane). Western Blot: Monoglyceride Lipase Antibody [ABIN4091190] - Monoglyceride Lipase Antibody (0.5ug/ml) staining of Human Adipose lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 5 to 7 Days
$408.19
Details
Human Chicken Un-conjugated WB Western Blot: Monoglyceride Lipase Antibody [ABIN250940] - Western Blot: E coli-derived fusion protein as test antigen. Affinity-purified IgY dilution: 1:2000, Goat anti-IgY-HRP dilution: 1:1000. Colorimetric method for signal development. ( anti-MGLL ) 0.05 mg Log in to see 7 to 9 Days
$538.13
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-MGLL Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: ACHN cell lysate WB Suggested Anti-MGLL  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:1562500  Positive Control: ACHN cell lysate  MGLL is supported by BioGPS gene expression data to be expressed in ACHN 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated FACS, IF, IHC, WB Anti-MGLL mouse monoclonal antibody (ABIN2454564) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY MGLL (RC218358). HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY MGLL (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-MGLL. 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated FACS, IHC, WB HEK293T cells transfected with either RC218358 overexpress plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-MGLL antibody (ABIN2454596), and then analyzed by flow cytometry. HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY MGLL (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-MGLL. 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated IF, IHC, WB Anti-MGLL mouse monoclonal antibody (ABIN2454695) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY MGLL (RC218358). HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY MGLL (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-MGLL. 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated IHC, WB HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY MGLL (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-MGLL. Immunohistochemical staining of paraffin-embedded Carcinoma of Human kidney tissue using anti-MGLL mouse monoclonal antibody. (ABIN2454563) 100 μL Log in to see 2 to 3 Days
$423.50
Details
Hamster Goat Un-conjugated IHC (p), ELISA, WB Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 7 to 9 Days
$451.00
Details

MGLL Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-MGLL Antibodies

  1. Human Polyclonal MGLL Primary Antibody for ELISA, WB - ABIN334436 : Blankman, Simon, Cravatt: A comprehensive profile of brain enzymes that hydrolyze the endocannabinoid 2-arachidonoylglycerol. in Chemistry & biology 2007 (PubMed)

  2. Human Polyclonal MGLL Primary Antibody for WB - ABIN250940 : Tang, Wang: YAP-mediated induction of monoacylglycerol lipase restrains oncogenic transformation. in Cellular signalling 2015 (PubMed)

More Antibodies against MGLL Interaction Partners

Human Monoglyceride Lipase (MGLL) interaction partners

  1. there was evidence that MGLL rs604300 genotype interacts with early life adversity to predict threat-related basolateral amygdala habituation, a neural phenotype linked to the endocannabinoid system and addiction

  2. This study unravels a novel mechanism of SND1 (show SND1 Antibodies) function and identifies MGLL as a unique tumor suppressor for HCC (show FAM126A Antibodies). MGLL might function as a homeostatic regulator of Akt (show AKT1 Antibodies) restraining its activation.

  3. Monoacylglycerol lipase sulfenylation might act as an intrinsic neuroprotective mechanism by potentiating 2-AG signaling at CB1 (show CNR1 Antibodies) receptors.

  4. The study identified monoacylglycerol lipase as a YAP (show YAP1 Antibodies) transcriptional target and an inhibitor of anchorage-dependent cell growth.

  5. Molecular dynamics and nudged elastic band simulations were used to explore the conformational transition pathway of the helix alpha4 of human monoacylglycerol lipase.

  6. role of monoacylglycerol lipase (MAGL) in the cancer progress

  7. Our findings establish that MAGL promotes metastases in nasopharyngeal carcinoma

  8. In subcutaneous adipose tissue, DAGL-a mRNA was upregulated and fatty acid amide hydrolase (FAAH (show FAAH Antibodies)) and monoacylglycerol lipase (MAGL) mRNAs were down-regulated in obese subjects, but the diets had no influence.

  9. In obese humans, FAAH (show FAAH Antibodies) or MGL (show CLEC10A Antibodies) activity in adipocytes is not affected by diabetes, dyslipidaemia or other markers of metabolic dysfunction.

  10. Mutation of Cys242 was also found to impair inhibition of monoacylglycerol lipase.

Mouse (Murine) Monoglyceride Lipase (MGLL) interaction partners

  1. Activities of adipose triglyceride lipase (ATGL (show PNPLA2 Antibodies)), hormone sensitive lipolitic enzyme (HSL (show LIPE Antibodies)) and monoacylglycerol lipase (MGL) were significantly higher (51 %, 38 %, 49 %) in the DE group than the HF group (p < 0.05). MGL (show CLEC10A Antibodies), there were no differences between the CO group, HF group, and DC group, with the DE group (70 %) being significantly higher (p < 0.05).

  2. MGL (show CLEC10A Antibodies) in astrocytes is an important regulator of 2-arachidonoylglyerol levels, arachidonic acid availability, and neuroinflammation.

  3. Genetic and pharmacological ablation of Magl attenuated centrally-mediated fever response.

  4. the results indicate that global MGL (show CLEC10A Antibodies) deletion leads to systemic changes that produce a leaner (show CACNA1A Antibodies) phenotype and an improved serum metabolic profile.

  5. This study showed that Genetic deletion of monoacylglycerol lipase leads to impaired cannabinoid receptor CBR (show CBR1 Antibodies) signaling and anxiety-like behavior.

  6. Suggest that organophosphate agents induce plasma hypertriglyceridemia in mouse through single or dual inhibition of FAAH (show FAAH Antibodies) or/and MAGL, apparently leading to overstimulation of cannabinoid signal regulating energy metabolism.

  7. Inactivation of Monoacylglycerol lipase robustly suppressed production and accumulation of beta-amyloid (Abeta (show APP Antibodies)) associated with reduced expression of beta-site amyloid precursor protein cleaving enzyme 1 (BACE1 (show BACE Antibodies)) in a mouse model of Alzheimer's disease.

  8. Data indicate that nerve growth factor (NGF) controls monoacylglycerol lipase (MGL) degradation in vitro and in vivo.

  9. The results therefore suggest a role for intestinal MGL (show CLEC10A Antibodies) in whole body energy balance via regulation of food intake as well as metabolic rate.

  10. MGL (show CLEC10A Antibodies) regulates 2-arachidonoylglycerol signaling rather broadly within a certain range of neural tissue, although MGL (show CLEC10A Antibodies) expression is heterogeneous and limited to a subset of nerve terminals and astrocytes.

MGLL Antigen Profile

Protein Summary

This gene encodes a serine hydrolase of the AB hydrolase superfamily that catalyzes the conversion of monoacylglycerides to free fatty acids and glycerol. The encoded protein plays a critical role in several physiological processes including pain and nociperception through hydrolysis of the endocannabinoid 2-arachidonoylglycerol. Expression of this gene may play a role in cancer tumorigenesis and metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene names and symbols associated with MGLL

  • monoglyceride lipase (mgll) antibody
  • monoglyceride lipase (MGLL) antibody
  • monoglyceride lipase (13L) antibody
  • monoglyceride lipase (YMTVg13L) antibody
  • Monoglyceride lipase (EHI_044210) antibody
  • Monoglyceride lipase (EHI_045330) antibody
  • monoglyceride lipase (TATV_DAH68_039) antibody
  • Monoglyceride lipase (mgll) antibody
  • monoglyceride lipase (Mgll) antibody
  • AA589436 antibody
  • cb909 antibody
  • HU-K5 antibody
  • HUK5 antibody
  • Magl antibody
  • MGC84195 antibody
  • Mgl antibody
  • mgll antibody
  • wu:fc66g01 antibody
  • zgc:56561 antibody

Protein level used designations for MGLL

monoglyceride lipase , Monoglyceride lipase , lysophospholipase homolog , monoacylglycerol lipase , MGL

GENE ID SPECIES
378960 Danio rerio
416024 Gallus gallus
447764 Xenopus laevis
739167 Pan troglodytes
918715 Yaba-like disease virus
2943660 Yaba monkey tumor virus
3406682 Entamoeba histolytica HM-1:IMSS
3411603 Entamoeba histolytica HM-1:IMSS
4238603 Taterapox virus
5656658 Tanapox virus
100127203 Xenopus (Silurana) tropicalis
100194972 Salmo salar
11343 Homo sapiens
476511 Canis lupus familiaris
100233193 Sus scrofa
505290 Bos taurus
23945 Mus musculus
29254 Rattus norvegicus
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