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Epithelial mucins, such as MUC13, are a family of secreted and cell surface glycoproteins expressed by ductal and glandular epithelial tissues (Williams et al., 2001 [PubMed 11278439]).[supplied by OMIM, Jul 2008].. Additionally we are shipping MUC13 Antibodies (75) and MUC13 Kits (17) and many more products for this protein.
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Results from this study demonstrate that MUC13 Functionally interacts and activates HER2 (show ERBB2 Proteins) at p1248 in PDAC cells, leading to stimulation of HER2 (show ERBB2 Proteins) signaling cascade, including ERK1/2, FAK (show PTK2 Proteins), AKT (show AKT1 Proteins) and PAK1 (show PAK1 Proteins) as well as regulation of the growth, cytoskeleton remodeling and motility, invasion of PDAC cells-all collectively contributing to PDAC progression.
High MUC13 expression is associated with renal cell carcinoma (show MOK Proteins) and drug resistance.
A combination of MUC13/MUC20 (show MUC20 Proteins) expression was a potential prognostic marker for patients with ESCC, who received neoadjuvant chemotherapy followed by surgery.
Results show that pancreatic ductal adenocarcinoma cells express higher levels of MUC13 and is associated with poor outcome when expressed at low level.
Based on nasopharyngeal MUC13 gene expression in readily available Nasopharyngeal aspirate samples , we can discriminate between severity of disease in Respiratory syncytial virus infected infants.
These results suggest miR (show MLXIP Proteins)-145 as a novel regulator of MUC13 in pancreatic cancer.
Overexpression of MUC13 increased cell growth, colony formation, cell migration, and invasion in colon cancer cells.
MUC13 is epigenetically regulated in ovarian cancer.
Overexpression of MUC13 is associated with pancreatic neuroendocrine tumors.
GALNT14 (show GALNT14 Proteins) may contribute to ovarian carcinogenesis through aberrant glycosylation of MUC13.
An orphan gene or trans-acting element present in the MUC13 gene region has an effect on the glycosylation of F4 binding proteins in E coli.
Susceptibility towards enterotoxigenic Escherichia coli F4ac diarrhea is governed by the MUC13 gene in pigs
This study suggests that expression of MUC13 and MUC20 (show MUC20 Proteins) is not related to the susceptibility of piglets to enterotoxigenic E. coli-F4ac.
MUC13 is in strong linkage disequilibrium with the ETEC F4ab/ac receptor locus
these data indicate that combining chemotherapy and MUC13 antagonism could improve the treatment of metastatic cancers
Muc13 was upregulated in the fundus of the stomach already 1 day after infection with Helicobacter heilmannii.
these studies demonstrate that MUC1 (show MUC1 Proteins) and MUC13 are important components of gastrointestinal homeostasis and that disruption or inappropriate expression of these mucins could predispose to infectious and inflammatory disease and inflammation-induced cancer.
hypothesize that NJ-1(+)megakaryocytes (MKs (show MKKS Proteins)) are immature MKs (show MKKS Proteins) and the NJ-1 molecule is involved in MK adhesion to endothelial cells [NJ-1]
Epithelial mucins, such as MUC13, are a family of secreted and cell surface glycoproteins expressed by ductal and glandular epithelial tissues (Williams et al., 2001
mucin 13, cell surface associated
, down-regulated in colon cancer 1
, mucin 13, epithelial transmembrane
, mucin 13A
, mucin 13B
, lymphocyte antigen 64
, cell surface antigen 114/A10