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Mucin 2, Oligomeric Mucus/gel-Forming Proteins (MUC2)

MUC2 encodes a member of the mucin protein family. Additionally we are shipping MUC2 Antibodies (239) and MUC2 Kits (42) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
MUC2 17831  
MUC2 4583 Q02817
Rat MUC2 MUC2 24572  
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Top MUC2 Proteins at antibodies-online.com

Showing 6 out of 11 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Yeast Human His tag 50 μg Log in to see 31 to 36 Days
$341.00
Details
HOST_Escherichia coli (E. coli) Human His-SUMO Tag 50 μg Log in to see 21 to 26 Days
$341.00
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 11 to 13 Days
$683.10
Details
HOST_Escherichia coli (E. coli) Mouse His tag 100 μg Log in to see 11 to 13 Days
$795.30
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 9 to 19 Days
$889.07
Details
HOST_Escherichia coli (E. coli) Mouse Un-conjugated   100 μg Log in to see 9 to 19 Days
$904.80
Details

MUC2 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human ,
,

More Proteins for Mucin 2, Oligomeric Mucus/gel-Forming (MUC2) Interaction Partners

Mouse (Murine) Mucin 2, Oligomeric Mucus/gel-Forming (MUC2) interaction partners

  1. This triggers calcium ion-dependent compound exocytosis of Muc2 mucin (show SLC13A2 Proteins) from the senGC and generates an intercellular gap junction signal; in turn, this signal induces Muc2 secretion from adjacent goblet cells in the upper crypt, which expels bacteria.

  2. HIF-1alpha (show HIF1A Proteins) inhibition decreases MUC2 production and mucinous tumor growth, providing a preclinical rationale for the use of HIF-1alpha (show HIF1A Proteins) inhibitors to treat patients with PMP

  3. colitic Muc2-/- mice have reduced colon CD103 (show ITGAE Proteins)+ CD11b (show ITGAM Proteins)- dendritic cells and increased CD103 (show ITGAE Proteins)- CD11b (show ITGAM Proteins)+ phagocytes.

  4. expression of MUC2 mRNA is found to be more expressed in Eimeria infected females than males

  5. MUC2 silencing increases interleukin (IL)-6 (show IL6 Proteins) secretion by colon cancer cells.

  6. These results suggest that SAA3 (show SAA3 Proteins) plays a role in host innate immunity in the colon by up-regulating MUC2 mucin (show SLC13A2 Proteins) production, which builds a physiological barrier of colonic epithelia against bacterial invasion.

  7. Alterations in the immune compartment due to intestinal bacterial breach in Muc2-/- mice, were investigated.

  8. Meprin beta (show MEP1B Proteins) is an endogenous zinc-dependent metalloprotease (show ADAMTS7 Proteins) now shown to cleave the N-terminal region of the MUC2 mucin (show SLC13A2 Proteins) at two specific sites.

  9. These data suggest that the intestinal mucus layer (Muc2) and core 3 O-glycosylation play critical roles in controlling Salmonella intestinal burdens and intestinal epithelial barrier function, respectively.

  10. Report regiospecific Muc2 O-glycan patterns in mouse stomach, small intestines and colon.

Human Mucin 2, Oligomeric Mucus/gel-Forming (MUC2) interaction partners

  1. Immunohistochemistry showed a reverse correlation between MUC2 and Notch3 or Jagged1 (P = 0.033 and P = 0.005, respectively) and between MUC5AC and Jagged1 or Hes1

  2. Our results unraveled an important regulatory role for MUC2 mucin (show SLC13A2 Proteins) in human beta-defensin2 mRNA and peptide production in a proinflammatory milieu

  3. There was no significant difference in MUC2 expression between chronic rhinosinusitis patients with and without bacterial biofilm formation.

  4. In ovarian mucinous tumors, MUC2 expression changes with the progression of benign to borderline and malignant tumours

  5. The genetic length variants in the central repetitive region of MUC2 were not associated with meconium ileus in cystic fibrosis (show S100A8 Proteins).

  6. The expression of a subset of mucins (MUC2, MUC6, MUC5B) was also correlated with sialyl-Tn expression in LS174T cells.

  7. There was no difference in the expression of deep MUC1 (show MUC1 Proteins), MUC2, MUC5AC, or MUC6 (show MUC6 Proteins) between the groups of gastric cancer and controls.

  8. The results indicated that the DNA methylation (show HELLS Proteins) status of MUC1 (show MUC1 Proteins), MUC2 and MUC4 (show MUC4 Proteins) in pancreatic juice matched with the mucin (show SLC13A2 Proteins) expression in tissue.

  9. Expression of Hath1 (show ATOH1 Proteins), Muc2, cyclin D1 (show CCND1 Proteins) and p27 (show PAK2 Proteins) in the xenograft tumors was also detected.

  10. Down-regulated expression of MUC-2, -4 and -5AC may be involved in pathogenesis.

Pig (Porcine) Mucin 2, Oligomeric Mucus/gel-Forming (MUC2) interaction partners

  1. identified a specific depletion of secreted MUC2 from goblet cells in Lawsonia intracellularis-infected pigs that correlated with the increased level of intracellular bacteria in crypt cells

  2. The structures of purified soluble porcine gastric (Muc5ac) and duodenal (Muc2) mucin (show SLC13A2 Proteins) solutions at neutral and acidic pH were examined using small-angle X-ray scattering and small-angle neutron scattering experiments

MUC2 Protein Profile

Protein Summary

This gene encodes a member of the mucin protein family. Mucins are high molecular weight glycoproteins produced by many epithelial tissues. The protein encoded by this gene is secreted and forms an insoluble mucous barrier that protects the gut lumen. The protein polymerizes into a gel of which 80% is composed of oligosaccharide side chains by weight. The protein features a central domain containing tandem repeats rich in threonine and proline that varies between 50 and 115 copies in different individuals. Alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.

Gene names and symbols associated with MUC2

  • mucin 2 (Muc2)
  • mucin 2 (MUC2)
  • mucin 2, oligomeric mucus/gel-forming (MUC2)
  • mucin 2, oligomeric mucus/gel-forming (Muc2)
  • small intestinal mucin (LOC100127145)
  • 2010015E03Rik protein
  • HH-Muc protein
  • MCM protein
  • MLP protein
  • MUC-2 protein
  • SMUC protein
  • wnn protein

Protein level used designations for MUC2

colonic mucin , mucin-2 , secreted gel-forming mucin , intestinal mucin-2 , mucin 2, intestinal/tracheal , mucin-like protein , MUC-2

GENE ID SPECIES
17831 Mus musculus
789571 Bos taurus
100724045 Cavia porcellus
4583 Homo sapiens
24572 Rattus norvegicus
423101 Gallus gallus
100127145 Sus scrofa
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