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MMRN2 encodes a protein belonging to the member of elastin microfibril interface-located (EMILIN) protein family. Additionally we are shipping Multimerin 2 Antibodies (27) and Multimerin 2 Kits (11) and many more products for this protein.
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Results suggest that CLEC14A (show CLEC14A Proteins)-MMRN2 binding has a role in inducing sprouting angiogenesis during tumor growth, which has the potential to be manipulated in future antiangiogenic therapy design.
CLEC14A (show CLEC14A Proteins) is a matrix component which binds to MMRN2 in the process of endothelial cells transformation in tumor angiogenesis.
MMRN2 as a crucial player in the regulation of EC function, neo-angiogenesis and hence tumor growth
Mmrn2 interacts with anthrax protective antigen.
This gene encodes a protein belonging to the member of elastin microfibril interface-located (EMILIN) protein family. This family member is an extracellular matrix glycoprotein that can interfere with tumor angiogenesis and growth. It serves as a transforming growth factor beta antagonist and can interfere with the VEGF-A/VEGFR2 pathway. A related pseudogene has been identified on chromosome 6.
, elastin microfibril interfacer 3
, EMILIN-like protein EndoGlyx-1
, elastin microfibril interface located protein 3
, endoGlyx-1 p125/p140 subunit