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Multivesicular Body Subunit 12B (MVB12B) ELISA Kits

The protein encoded by MVB12B is a component of the ESCRT-I complex, a heterotetramer, which mediates the sorting of ubiquitinated cargo protein from the plasma membrane to the endosomal vesicle. Additionally we are shipping MVB12B Proteins (4) and and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human MVB12B MVB12B 89853 Q9H7P6
Anti-Mouse MVB12B MVB12B 72543 Q6KAU4
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More ELISA Kits for MVB12B Interaction Partners

Human Multivesicular Body Subunit 12B (MVB12B) interaction partners

  1. Study suggests a novel association between SNPs in FAM125B andintra-ocular pressure in the TwinsUK cohort.

  2. The 1.3-A atomic resolution crystal structure of the MVB12B MABP domain reveals a beta (show SUCLA2 ELISA Kits)-prism fold, a hydrophobic membrane-anchoring loop, and an electropositive phosphoinositide-binding patch.

  3. These results suggest that the expression of MVB12B may be normally suppressed through the ubiquitin-proteasome pathway that simultaneously regulates the fate of MVB12A (show FAM125A ELISA Kits) and the functions of ESCRT-I (show VPS28 ELISA Kits).

MVB12B Antigen Profile

Antigen Summary

The protein encoded by this gene is a component of the ESCRT-I complex, a heterotetramer, which mediates the sorting of ubiquitinated cargo protein from the plasma membrane to the endosomal vesicle. ESCRT-I complex plays an essential role in HIV budding and endosomal protein sorting. Depletion and overexpression of this and related protein (MVB12A) inhibit HIV-1 infectivity and induce unusual viral assembly defects, indicating a role for MVB12 subunits in regulating ESCRT-mediated virus budding. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with MVB12B

  • multivesicular body subunit 12B (MVB12B) antibody
  • multivesicular body subunit 12B (Mvb12b) antibody
  • 2610200O14Rik antibody
  • 2610528K11Rik antibody
  • AI414895 antibody
  • C9orf28 antibody
  • Fam125b antibody

Protein level used designations for MVB12B

ESCRT-I complex subunit MVB12B , family with sequence similarity 125, member B

GENE ID SPECIES
89853 Homo sapiens
72543 Mus musculus
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