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Murine Retrovirus Integration Site 1 Homolog Proteins (MRVI1)

MRVI1 is similar to a putative mouse tumor suppressor gene (Mrvi1) that is frequently disrupted by mouse AIDS-related virus (MRV). Additionally we are shipping Murine Retrovirus Integration Site 1 Homolog Kits (3) and Murine Retrovirus Integration Site 1 Homolog Antibodies (3) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
MRVI1 17540 Q9WUX5
MRVI1 10335 Q9Y6F6
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Top Murine Retrovirus Integration Site 1 Homolog Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 59 to 64 Days
$6,052.17
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 59 to 64 Days
$8,623.45
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

MRVI1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human ,

More Proteins for Murine Retrovirus Integration Site 1 Homolog (MRVI1) Interaction Partners

Mouse (Murine) Murine Retrovirus Integration Site 1 Homolog (MRVI1) interaction partners

  1. cGKIbeta signaling via IRAG is essential for regulation of smooth muscle tone and of intracellular calcium by NO and by atrial natriuretic peptide (show NPPA Proteins).

  2. conclude that cGMP-dependent relaxation of hormone receptor (show NR4A1 Proteins)-triggered smooth muscle contraction essentially depends on the interaction of cGKI (show PRKG1 Proteins)-IRAG with IP(3)RI

  3. Reports use of non-AUG (CUG) translation initiation codon in one of the transcript variants of MRVI1 gene in mouse and human.

Human Murine Retrovirus Integration Site 1 Homolog (MRVI1) interaction partners

  1. In the present study we analyzed the structure and function of the human IRAG/MRVI1 gene

  2. IRAG is required for PKG1beta-regulated cyclic calcium release during motility of osteoclasts

  3. IRAG appears to be essentially involved in the NO/cGK (show PRKG1 Proteins)-dependent inhibition of InsP(3)-dependent Ca(2 (show CA2 Proteins)+)-signaling in colonic smooth muscle

  4. cGMP-dependent protein kinase (show CDK7 Proteins) Ibeta binds to TFII-I (show GTF2I Proteins) and IRAG through a common interaction motif

  5. These findings reveal that interaction between IRAG and InsP3RI has a central role in NO/cGMP-dependent inhibition of platelet aggregation and in vivo thrombosis.

  6. Reports use of non-AUG (CUG) translation initiation codon in one of the transcript variants of MRVI1 gene in mouse and human.

Cow (Bovine) Murine Retrovirus Integration Site 1 Homolog (MRVI1) interaction partners

  1. cGKIbeta signaling via IRAG is essential for regulation of smooth muscle tone and of intracellular calcium by NO and by atrial natriuretic peptide (show NPPA Proteins).

  2. cGMP-dependent protein kinase (show CDK7 Proteins) Ibeta binds to TFII-I (show GTF2I Proteins) and IRAG through a common interaction motif

Murine Retrovirus Integration Site 1 Homolog (MRVI1) Protein Profile

Protein Summary

This gene is similar to a putative mouse tumor suppressor gene (Mrvi1) that is frequently disrupted by mouse AIDS-related virus (MRV). The encoded protein, which is found in the membrane of the endoplasmic reticulum, is similar to Jaw1, a lymphoid-restricted protein whose expression is down-regulated during lymphoid differentiation. This protein is a substrate of cGMP-dependent kinase-1 (PKG1) that can function as a regulator of IP3-induced calcium release. Studies in mouse suggest that MRV integration at Mrvi1 induces myeloid leukemia by altering the expression of a gene important for myeloid cell growth and/or differentiation, and thus this gene may function as a myeloid leukemia tumor suppressor gene. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene, and alternative translation start sites, including a non-AUG (CUG) start site, are used.

Gene names and symbols associated with MRVI1

  • MRV integration site 1 (Mrvi1)
  • murine retrovirus integration site 1 homolog (MRVI1)
  • BB115629 protein
  • IRAG protein
  • JAW1L protein
  • Ris1 protein

Protein level used designations for MRVI1

JAW1-related protein MRVI1 , inositol 1,4,5-triphosphate receptor-associated cGMP kinase substrate , inositol 1,4,5-trisphosphate receptor-associated cGMP kinase substrate , murine retrovirus integration site 1 protein , protein MRVI1 , retroviral integration site 1 , IP3R-associated cGMP kinase substrate , IP3 receptor associated cGMP kinase substrate

GENE ID SPECIES
17540 Mus musculus
10335 Homo sapiens
281918 Bos taurus
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