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The protein encoded by MSC is a transcriptional repressor capable of binding an E-box element either as a homodimer or as a heterodimer with E2A in vitro. Additionally we are shipping Musculin Proteins (6) and Musculin Kits (4) and many more products for this protein.
Showing 10 out of 55 products:
Human Polyclonal MSC Primary Antibody for ELISA, WB - ABIN256631
Massari, Rivera, Voland, Quong, Breit, van Dongen, de Smit, Murre: Characterization of ABF-1, a novel basic helix-loop-helix transcription factor expressed in activated B lymphocytes. in Molecular and cellular biology 1998
this study shows that musculin inhibits human T-helper 17 cell response to interleukin 2 (show IL2 Antibodies) by controlling STAT5B (show STAT5B Antibodies) activity
results demonstrate that ABF-1 facilitates formation of memory B cells but prevents plasma cell differentiation.
role in repressing lymphotoxin alpha
ABF-1 is frequently silenced by promoter methylation in follicular lymphoma, diffuse large B-cell lymphoma and Burkitt's lymphoma.
this study shows that MSC-deficient TGFb (show TGFB1 Antibodies)-induced Treg cells are unable to suppress Th2 cell responses, and that MSC-deficient mice spontaneously develop gut (show GUSB Antibodies) and lung inflammation with age
MyoR modulates cardiac conduction by repressing Gata4 (show GATA4 Antibodies).
MyoR is a transcription factor selectively up-regulated in CD4 (show CD4 Antibodies) T cells during Tfh cell differentiation
Basic helix-loop-helix transcriptional factor MyoR regulates BMP-7 (show BMP7 Antibodies) in acute kidney injury.
Data show that correct levels of expression of Myf5 (show MYF5 Antibodies) and MyoD (show MYOD1 Antibodies) during mouse craniofacial development result from activation by musculin and TCF21 (show TCF21 Antibodies) through direct binding to specific enhancers.
a feed-forward loop where MyoD (show MYOD1 Antibodies) indirectly down-regulates MyoR via miR (show MLXIP Antibodies)-378
findings identify MyoR and capsulin (show TCF21 Antibodies) as unique transcription factors for the development of specific head muscles
MyoR may serve as a repressor of embryonal endoderm differentiation.
Our results suggest that musculin/MyoR may play important roles not only in developmental processes but also in regenerative processes in adult tissue.
The protein encoded by this gene is a transcriptional repressor capable of binding an E-box element either as a homodimer or as a heterodimer with E2A in vitro. The encoded protein also forms heterodimers with E2A proteins in vivo. This protein is capable of inhibiting the transactivation capability of E47, an E2A protein, in mammalian cells. This gene is a downstream target of the B-cell receptor signal transduction pathway.
, musculin (activated B-cell factor-1)
, activated B-cell factor 1, homolog of mouse musculin
, activated B-cell factor-1
, class A basic helix-loop-helix protein 22
, myogenic repressor