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Muskelin is an intracellular protein that acts as a mediator of cell spreading and cytoskeletal responses to the extracellular matrix component thrombospondin I (MIM 188060) (Adams et al., 1998 [PubMed 9724633]).[supplied by OMIM, Mar 2008].. Additionally we are shipping Muskelin 1, Intracellular Mediator Containing Kelch Motifs Antibodies (44) and Muskelin 1, Intracellular Mediator Containing Kelch Motifs Proteins (5) and many more products for this protein.
RanBPM, ARMC8alpha, ARMC8beta, Muskelin, p48EMLP, and p44CTLH form complexes in cells
These novel findings identify a role for muskelin-RanBP9 (show RANBP9 ELISA Kits) complex in pathways that integrate cell morphology regulation and nucleocytoplasmic communication.
The first crystal structure of mouse muskelin discoidin domain (MK-DD) is reported at 1.55 A resolution, which reveals a distorted eight-stranded beta-barrel with two short alpha-helices at one end of the barrel.
This novel interaction between TBX20b and MKLN1 may help elucidate new regulatory mechanisms within heart development.
Muskelin regulates retrograde actin filament and microtubule-dependent GABA-A receptor trafficking.
expression of muskelin during embryonic development in muscle tissues, multiple epithelia & brain; findings show PKC (show PKC ELISA Kits) activation or inhibition regulates the profile of endogenous muskelin isoelectric variants; muskelin is a substrate for PKCalpha (show PKCa ELISA Kits) in vitro
Muskelin represents a multifunctional protein associated with membranes and/or large protein complexes in most neurons of the central nervous system.
Muskelin is an intracellular protein that acts as a mediator of cell spreading and cytoskeletal responses to the extracellular matrix component thrombospondin I (MIM 188060) (Adams et al., 1998
, muskelin 1, intracellular mediator containing kelch motifs