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anti-Mutated in Colorectal Cancers (MCC) Antibodies

MCC is a candidate colorectal tumor suppressor gene that is thought to negatively regulate cell cycle progression. Additionally we are shipping MCC Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
MCC 4163 P23508
MCC 328949  
MCC 307449  
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Top anti-MCC Antibodies at antibodies-online.com

Showing 10 out of 68 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse Un-conjugated IHC (f), IF, IP, WB Western blot analysis of MCC on a human endothelial cell lysate. Lane 1: 1:500, lane 2: 1:1000, lane 3: 1:2000 dilution of the anti- MCC antibody. Immunofluorescence staining of human endothelial cells. 50 μg Log in to see 5 to 6 Days
$205.42
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 4 to 6 Days
$200.00
Details
Human Rabbit Un-conjugated IHC (p), WB IHC-P Image Immunohistochemical analysis of paraffin-embedded human colon carcinoma, using MCC, antibody at 1:250 dilution. WB Image Sample (30 ug of whole cell lysate) A: IMR32 7.5% SDS PAGE antibody diluted at 1:1000 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB MCC Antibody (Center)  western blot analysis in U937 cell line lysates (35ug/lane).This demonstrates the MCC antibody detected the MCC protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated WB Western blot analysis of MCC over-expressed 293 cell line, cotransfected with MCC Validated Chimera RNAi used as specificity and loading control. Western Blot analysis of MCC expression in transfected 293T cell line by MCC monoclonal antibody (M01), clone 1A7. Lane 1: MCC transfected lysate(93.1 KDa). Lane 2: Non-transfected lysate. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated WB   100 μg Log in to see 8 to 10 Days
$463.83
Details
Human Rabbit Un-conjugated IP, WB MCC MaxPab rabbit polyclonal antibody. Western Blot analysis of MCC expression in mouse lung. MCC MaxPab rabbit polyclonal antibody. Western Blot analysis of MCC expression in rat brain. 100 μL Log in to see 9 Days
$418.57
Details
Human Mouse Un-conjugated WB Western Blot analysis of MCC expression in transfected 293T cell line by MCC MaxPab polyclonal antibody.Lane1:MCC transfected lysate(91.19 KDa).Lane2:Non-transfected lysate. 50 μL Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated WB 400 μL Log in to see 6 Days
$457.14
Details

MCC Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-MCC Antibodies

  1. Human Monoclonal MCC Primary Antibody for IHC (f), IF - ABIN968147 : Ashton-Rickardt, Wyllie, Bird, Dunlop, Steel, Morris, Piris, Romanowski, Wood, White: MCC, a candidate familial polyposis gene in 5q.21, shows frequent allele loss in colorectal and lung cancer. in Oncogene 1991 (PubMed)
    Show all 5 references for ABIN968147

More Antibodies against MCC Interaction Partners

Zebrafish Mutated in Colorectal Cancers (MCC) interaction partners

  1. The PDZ domain protein (show INADL Antibodies) Mcc is a novel effector of non-canonical Wnt (show WNT2 Antibodies) signaling during convergence and extension in zebrafish.

Human Mutated in Colorectal Cancers (MCC) interaction partners

  1. Our results indicate that in sharp contrast to its tumor suppressive role in colorectal cancer, MCC functions as an oncogene (show RAB1A Antibodies) in B cells

  2. cytoplasmic MCC-DBC1 (show DBC1 Antibodies) interaction sequesters DBC1 (show DBC1 Antibodies) away from the nucleus, thereby removing a brake on DBC1 (show DBC1 Antibodies) nuclear targets, such as SIRT1 (show SIRT1 Antibodies)

  3. targeted by miR (show MLXIP Antibodies)-494, which is overexpressed in hepatocellular carcinoma

  4. MCC regulates lamellipodia formation by binding to Scrib (show SCRIB Antibodies) and its downstream partner Myosin-IIB (show MYH10 Antibodies) in a multiprotein complex.

  5. we have shown that promoter methylation of the APC (show APC Antibodies) gene does not extend to the neighbouring MCC gene in lung cancer, but LOH is found at both loci.

  6. Promoter methylated MCC is associated with inflammatory bowel disease in colorectal cancer.

  7. MCC is a nuclear, beta-catenin-interacting protein (show CTNNBIP1 Antibodies) that can act as a potential tumor suppressor in the serrated colorectal cancer pathway by inhibiting Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) signal transduction.

  8. Results identify MCC as a potential scaffold protein (show HOMER1 Antibodies) regulating cell movement and able to bind Scrib (show SCRIB Antibodies), beta-catenin (show CTNNB1 Antibodies) and NHERF1 (show SLC9A3R1 Antibodies)/2.

Mouse (Murine) Mutated in Colorectal Cancers (MCC) interaction partners

  1. Our results indicate that in sharp contrast to its tumor suppressive role in colorectal cancer, MCC functions as an oncogene (show RAB1A Antibodies) in B cells

MCC Antigen Profile

Protein Summary

This gene is a candidate colorectal tumor suppressor gene that is thought to negatively regulate cell cycle progression. The orthologous gene in the mouse expresses a phosphoprotein associated with the plasma membrane and membrane organelles, and overexpression of the mouse protein inhibits entry into S phase. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with MCC

  • mutated in colorectal cancers (MCC) antibody
  • mutated in colorectal cancers (mcc) antibody
  • mutated in colorectal cancers (LOC100354734) antibody
  • mutated in colorectal cancers (Mcc) antibody
  • D18Ertd451e antibody
  • E330037C19 antibody
  • MCC antibody
  • MCC1 antibody
  • RGD1561988 antibody

Protein level used designations for MCC

mutated in colorectal cancers , colorectal mutant cancer protein

GENE ID SPECIES
100064404 Equus caballus
415603 Gallus gallus
462002 Pan troglodytes
694270 Macaca mulatta
100015680 Monodelphis domestica
100216150 Xenopus (Silurana) tropicalis
100354734 Oryctolagus cuniculus
100473268 Ailuropoda melanoleuca
100537329 Danio rerio
4163 Homo sapiens
328949 Mus musculus
307449 Rattus norvegicus
611208 Canis lupus familiaris
616704 Bos taurus
Selected quality suppliers for anti-MCC (MCC) Antibodies
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