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MUTED encodes a component of BLOC-1 (biogenesis of lysosome-related organelles complex 1). Additionally we are shipping Muted Homolog (Mouse) Antibodies (25) and Muted Homolog (Mouse) Kits (3) and many more products for this protein.
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Human MUTED Protein expressed in Escherichia coli (E. coli) - ABIN1098338
Ciciotte, Gwynn, Moriyama, Huizing, Gahl, Bonifacino, Peters: Cappuccino, a mouse model of Hermansky-Pudlak syndrome, encodes a novel protein that is part of the pallidin-muted complex (BLOC-1). in Blood 2003
Show all 2 references for ABIN1098338
The muted protein is involved in the selective export of CgA (show CGA Proteins) during the biogenesis of large dense-core vesicle.
This gene encodes a component of BLOC-1 (biogenesis of lysosome-related organelles complex 1). Components of this complex are involved in the biogenesis of organelles such as melanosomes and platelet-dense granules. A mouse model for Hermansky-Pudlak Syndrome is mutated in the murine version of this gene. Alternative splicing results in multiple transcript variants. Read-through transcription exists between this gene and the upstream EEF1E1 (eukaryotic translation elongation factor 1 epsilon 1) gene, as well as with the downstream TXNDC5 (thioredoxin domain containing 5) gene.
BLOC-1 subunit 5
, biogenesis of lysosome-related organelles complex 1 subunit 5
, muted homolog
, protein Muted homolog
, Protein Muted homolog